Foods That Heal · Broths & Soups

Bone Broth: Benefits, Nutrition, Recipes & How to Make It

What bone broth is, what's in a cup, how it supports your gut lining, joints, skin and sleep, how much to drink a day, and how to make chicken and beef bone broth at home.

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Evidence-based56 sources citedUpdated November 4, 2026
Published Nov 4, 2026Last updated Nov 4, 2026Editorial policyMedical review policyFact-checking policy
A white bowl of golden bone broth topped with a sprig of dill, with fresh sage, chives, thyme and whole peppercorns on a white table
A warm bowl of golden bone broth, ready to sip between meals or before bed.
The Dr. Axe Score™
6.0/10
Overall Dr. Axe Score · Bone Broth

Bone broth scores 6.0 for its central place in four of Dr. Axe's protocols, with studies of chicken broth and soup in people and many trials of the collagen, gelatin, glutamine and glycine it carries.

Scientific Evidence
5.6/10
Human studies of chicken broth and soup (rehydration, nasal mucus flow, fullness, exercise), a Mayo Clinic review of its nutrients, animal studies, and many trials of collagen, gelatin, glutamine and glycine in supplement form.
Antioxidant & Anti-Inflammatory
5.6/10
Glycine is a building block of glutathione; chicken soup slowed inflammatory white blood cells in the lab, and beef bone broth cut the activity of the gene for the inflammatory messenger IL-6 94.70% in the colons of mice with colitis.
Clinical Effectiveness
7.6/10
The number one food in Dr. Axe's Healing Leaky Gut Protocol (8 to 16 oz a day) and a daily food in his Anti-Inflammatory Reset, SIBO and Mitochondrial Longevity Protocols, used with his patients for digestive healing.
Nutrient Density
5.2/10
Per cup of USDA home-prepared stock, 4.73 to 6.05 g of protein for 31 to 86 calories, up to 24% of the daily value for niacin (chicken) and 67% for vitamin B12 (fish); most minerals under 10%.
Why this score?
Why Bone Broth scores 6.0 / 10

    Weighting: Evidence 30% · Antioxidant & Anti-Inflammatory 25% · Clinical Effectiveness 25% · Nutrient Density 20% (5.6×0.30 + 5.6×0.25 + 7.6×0.25 + 5.2×0.20 = 1.68 + 1.40 + 1.90 + 1.04 = 6.02, shown as 6.0). How we score

    A transparent, weighted index built for foods. See how it’s calculated →
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    Bone broth at a glance

    Bone broth is the bones, cartilage and connective tissue of chicken, beef, lamb or fish simmered for many hours, and it's one of the most healing foods you can make, rich in the gelatin, glycine and proline your gut lining, joints and skin are built from.12

    • What it does: gives your gut lining its building blocks (it's the number one food in my Healing Leaky Gut Protocol), supports your joints and skin, rehydrates you better than plain water and, with its glycine, helps you wind down at night345
    • How much: about a cup (8 ounces) most days, and 8 to 16 ounces a day, ideally 16, while you're healing your gut63
    • How to use it: sip it warm between meals or in the evening, cook soups, rice and quinoa in it, or blend it into a warm breakfast smoothie378
    • How to make it: simmer pasture-raised chicken bones and feet, or grass-fed beef knucklebones, with vegetables, herbs and a splash of apple cider vinegar for 24 to 48 hours

    Bone broth is made by simmering the bones, cartilage and connective tissue of chicken, beef, lamb or fish for many hours, until the collagen they hold melts into the water as gelatin, along with amino acids such as glycine, proline and glutamine.19 It's one of the most healing foods of all time, because it gives your gut lining, joints and skin the very building blocks they're made of.23

    Nearly a third of the protein in your body is collagen, yet most of us eat the muscle meat and throw away the bones, skin and cartilage, the parts richest in it.10 So when your digestion feels off, your joints ache or your skin starts losing its bounce, part of what's behind it can be a body running short on the raw materials it repairs itself with. Bone broth puts those parts back on your plate, in a warm cup that's gentle on your stomach.

    Around 2016, when I was writing about bone broth and collagen, I started using broth with patients to help them heal from chronic digestive issues.11 Today it's a daily food in four of my protocols, from gut healing to longevity, and it's simple enough to make in any kitchen.312613

    Made by simmering the bones and ligaments of beef, chicken, fish, and lamb, this nourishing food was a staple for our ancestors, who used every part of an animal as sustenance. … The cooking process triggers the release of healing compounds found within the animal tissue, like collagen, and its amino acids, proline, hydroxyproline, glycine, and glutamine, which help preserve youthful skin and joints.Dr. Josh Axe, DC, DNM, CNSFrom Ancient Remedies (2021), p. 94

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    Did you know?

    • Collagen makes up about 30% of the protein in your body, and glycine sits at every third position along its chain, which is why collagen-rich foods like bone broth are so rich in glycine.914

    • In a food survey of 1,500 Irish adults, people ate only about 3.2 grams of collagen a day on average, and adults 65 and older about 2.9 grams.15

    • One modeling study estimated that the glycine your body makes, plus what a typical diet supplies, may fall about 10 grams a day short of what collagen building calls for.16

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    What is bone broth?

    Quick answer

    Bone broth is a long-simmered broth made from animal bones, cartilage and connective tissue, usually chicken, beef, lamb or fish, cooked with vegetables, herbs and a splash of vinegar until the collagen breaks down into gelatin.19 That gelatin is why a rich broth sets like jelly in the fridge, and it carries collagen's amino acids glycine, proline and hydroxyproline, along with glutamine.1

    Cooks use the words loosely, but the difference comes down to what goes in the pot and how long it stays there. A broth is usually simmered from meat for an hour or two and a stock from bones for a few hours. Bone broth simmers bones, joints and cartilage for a day or more, which pulls far more gelatin out of them. That long simmer is also why bone broth is so gentle on your stomach: its protein arrives already dissolved in a warm liquid.

    A short history of bone broth

    Bone broth has been used for thousands of years for health, for immunity and for longevity.17 In Chinese medicine, it was recommended with most of your meals, alongside carrots, celery and sweet potato.2 Chicken soup, meanwhile, earned a reputation as a remedy for colds that has lasted so long that modern researchers have tested it, both in the lab and in people.1819 Until recently, though, broth had almost disappeared from the modern diet.1

    Types of bone broth: chicken, beef, fish and more

    Any clean animal with bones can go into the pot (pork bones and shellfish stay out), and each one makes a slightly different broth.

    Chicken bone broth

    As I said in a show on supplements for adults over 40, "Chicken broth in particular might be the most beneficial because not only does it have collagen, it also has glucosamine, chondroitin and hyaluronic acid."17 When researchers analyzed a chicken-vegetable bone broth, they found hyaluronic acid and chondroitin sulfate in it. In rats with bone loss modeled on menopause, that broth raised bone mineral density.20 Chicken feet, necks and wings are the gelatin-rich parts (the collagen in them is the kind described in our guide to chicken collagen), and our chicken bone broth recipe uses all three, so it sets firmly when it chills. Cracking the bones of a roast chicken carcass before they go in lets the marrow simmer into the broth too.

    Beef bone broth

    Beef bone broth has a deeper, roasted flavor, and it's the leanest of the three, with 31 calories, 4.73 grams of protein and 444 milligrams of potassium in a cup of USDA's homemade beef stock.21 For the supplement form of the same protein, see our guide to bovine collagen. In the pot, knucklebones and other joint bones carry the cartilage that makes a beef broth gel, and our beef bone broth recipe roasts them first for flavor.

    Fish bone broth

    Fish broth is the quickest to make and the lightest to drink. Use the heads and frames of fish with fins and scales, such as cod, halibut or salmon. A cup of USDA's homemade fish stock brings 5.27 grams of protein, 10% of the daily value for phosphorus and 67% for vitamin B12.22 Its collagen is the kind sold as fish collagen.

    Lamb, goat and turkey broth

    Lamb and goat bones make a rich, savory broth and are handled like beef: roast them first, then simmer them low. Turkey works just like chicken, and the carcass from a holiday turkey makes one of the best pots of the year (the recipe is below).

    Bone broth nutrition facts (per cup)

    Quick answer

    A cup of homemade chicken stock has 86 calories, 6.05 grams of protein, 2.88 grams of fat and 8.47 grams of carbohydrate, with 24% of the daily value for niacin, 16% for riboflavin and 10% for selenium.23 Beef stock is leaner, with 31 calories and 4.73 grams of protein a cup, and fish stock brings 5.27 grams of protein and 67% of the daily value for vitamin B12.2122

    Calculated from USDA FoodData Central SR Legacy records for home-prepared stock (chicken FDC ID 172884, beef 172883, fish 172885) at each record's 1-cup weight; % Daily Value uses FDA adult label values. USDA keeps no separate record for 24-hour bone broth.232122

    Nutrient (1 cup)Chicken stock (240 g)Beef stock (240 g)Fish stock (233 g)
    Calories863137
    Protein6.05 g (12% DV)4.73 g (9% DV)5.27 g (11% DV)
    Fat2.88 g0.22 g1.89 g
    Carbohydrate8.47 g2.88 g0 g
    Sodium343 mg (15% DV)475 mg (21% DV)363 mg (16% DV)
    Potassium252 mg (5% DV)444 mg (9% DV)336 mg (7% DV)
    Phosphorus64.8 mg (5% DV)74.4 mg (6% DV)130 mg (10% DV)
    Magnesium9.6 mg (2% DV)16.8 mg (4% DV)16.3 mg (4% DV)
    Calcium7.2 mg (1% DV)19.2 mg (1% DV)7.0 mg (1% DV)
    Niacin3.79 mg (24% DV)2.09 mg (13% DV)2.77 mg (17% DV)
    Riboflavin0.204 mg (16% DV)0.218 mg (17% DV)0.177 mg (14% DV)
    Selenium5.28 µg (10% DV)2.88 µg (5% DV)2.33 µg (4% DV)
    Vitamin B120 µg0 µg1.61 µg (67% DV)

    A cup of homemade stock brings 4.73 to 6.05 grams of protein

    A cup of homemade stock brings 4.73 to 6.05 grams of protein1 cup of home-prepared stock (240 g chicken or beef, 233 g fish) · USDA records, no study population. Chicken stock (86 calories): 6.05 grams of protein per cup; Fish stock (37 calories): 5.27 grams of protein per cup; Beef stock (31 calories): 4.73 grams of protein per cup1 cup of home-prepared stock (240 g chicken or beef, 233 gfish) · USDA records, no study populationChicken stock(86 calories)6.05 grams of protein percupFish stock (37calories)5.27 grams of protein percupBeef stock (31calories)4.73 grams of protein percup
    Source: USDA FoodData Central, FDC IDs 172884, 172885 and 172883 [23, 22, 21]Grams of protein in one cup of each USDA home-prepared stock, with calories per cup in the labels.

    What stands out in that table is how much protein broth delivers for so few calories: beef stock gives you 4.73 grams for 31 calories, about 15 grams of protein per 100 calories.21 Broth also carries potassium, phosphorus and some magnesium, along with the sodium that helps you hold on to fluid.232122 Even with vinegar in the pot, calcium and magnesium stayed under 5% of daily needs per serving in lab tests of bone broths.24 So lean on leafy greens and other calcium-rich foods for that mineral, and let broth do what it does best, which is to bring you gelatin, glycine and protein in a warm, easy cup.

    Collagen, gelatin and glycine in bone broth

    Gelatin keeps collagen's unusual amino acid profile, heavy in glycine and proline, which your body uses to build and repair its own collagen in skin, cartilage, tendons and the gut lining.14 That makes bone broth one of the richest everyday food sources of glycine and proline. It also brings glutamine, an amino acid your gut cells use for fuel, which our guide to L-glutamine explains in more detail.25 Broth sits at the top of our list of the best collagen-rich foods, for exactly these reasons.

    How bone broth works in your body

    Chinese medicine has a principle called like supports like: eat the tissue you want to support, and bone broth may be the clearest example of it.26 When you drink it, your gut, joints and skin get the same building materials they're made of, a little like patching an old brick wall with bricks from the same kiln.

    Your gut lining is where those materials go to work. Its cells are held together by tight junctions, the seals that keep nutrients from leaking away and help keep inflammation down, and I recommend amino acid-rich foods like bone broth, collagen and bovine or fish gelatin to support them.10

    Glycine does a second job your liver depends on. It's one of the three building blocks of glutathione, the antioxidant your liver uses to detoxify, and a 2018 review argued that the glycine in your diet may set the limit on how much glutathione you make.27

    1A long, gentle simmer

    Hours of low heat pull collagen out of bones, skin and cartilage as gelatin, along with glycine, proline, hydroxyproline and glutamine,1 and chicken broth also carries hyaluronic acid and chondroitin sulfate.20

    2Building blocks for your gut lining

    A Mayo Clinic review ties broth's glutamine, glycine, proline and minerals to a stronger gut barrier,25 and in a placebo-controlled trial, glutamine powder (15 grams a day for 8 weeks) lowered gut permeability in adults with IBS with diarrhea.28

    3Raw materials for joints and skin

    In a review of 35 trials, collagen products, gelatin among them, eased osteoarthritis pain, and across 26 trials hydrolyzed collagen improved skin hydration and elasticity.2930

    4Glycine at night

    In rats, glycine helped the body cool down for sleep,31 and in a trial of 13 men with sleep complaints, a glycine-rich collagen drink before bed meant fewer night awakenings.5

    5Warm fluid and electrolytes

    Broth's sodium and potassium help you hold on to fluid, and after dehydration, chicken broth restored blood plasma volume better than plain water.4

    Bone broth works because it's high in glycine, proline and hydroxyproline. It's literally what your gut is made up of.Dr. Josh Axe, DC, DNM, CNSFrom Complete Guide to Healing Leaky Gut Naturally, The Dr. Josh Axe Show (2026), at 33:05

    Bone broth benefits: what it's good for

    Quick answer

    Bone broth is good for your gut lining, your joints and your skin, because it's made from the parts of the animal those tissues are built from.13 I use it first when the gut needs healing, and it's also a warm cup that's gentle on your stomach when you're sick, a good way to rehydrate and, with its glycine, a calming drink before bed.819432

    Where the research stands

    Bone broth's benefits rest on three kinds of evidence: Dr. Axe's protocols and its long traditional use, small studies of chicken broth and chicken soup in people, and trials of the nutrients broth carries, collagen, gelatin, glutamine and glycine, in supplement form. A randomized trial of bone broth itself for the gut, joints or skin hasn't been done yet, so each card names exactly what was studied.25294

    1

    Supports a healthy gut lining

    Emerging evidenceAnimal studyMayo Clinic review · placebo-controlled trial of glutamine powder in 106 adults · mouse colitis study

    Healing a leaky gut is the job I give bone broth first. It's the number one of the foods that heal in the Healing Leaky Gut Protocol, which lists broth's glycine, glutamine and collagen as the building blocks of new gut lining, and you sip it daily through the protocol's Replace and Repair steps.3 When your gut is raw, you want foods that are easy to digest, and as I've said, "The number one food for most people is bone broth."8

    A 2025 review by Mayo Clinic gastroenterologists found that broth's glutamine, glycine, proline and minerals support the gut barrier, especially in inflammatory bowel disease. The authors pointed to broth as a potential remedy for keeping that disease in remission.25 Glutamine, one of the amino acids broth carries, has the strongest human trial behind it. In a placebo-controlled trial of adults whose irritable bowel syndrome with diarrhea began after a gut infection, all with raised gut permeability, 5 grams of glutamine powder three times a day for 8 weeks eased symptoms by at least 50 points on a standard IBS scale in 79.6% of people, against 5.8% on placebo, and lowered their gut permeability score from 0.11 to 0.05, against 0.10 on placebo, among the 106 who finished.28

    In a study of mice with induced colitis (6 in each group), beef bone broth given for 10 days beforehand meant less colon damage, and the gene for IL-6, an inflammatory messenger, was 94.70% less active in their colons than in mice without broth.33 In a trial of 20 trained adults who each tried both, a marker of bacterial toxins in the blood rose during hard exercise only on placebo, not on collagen peptides (10 grams a day for a week), though gut permeability itself didn't differ.34 In the protocol's Repair step, food sensitivities begin to fade as the lining seals.3

    2

    Joint and cartilage support

    Emerging evidenceHuman studyReview of 35 RCTs · 3,165 people (collagen products, gelatin among them) · RCT of 147 athletes

    Your cartilage, tendons and ligaments are built largely from collagen, and bone broth hands them its raw materials in food form.14 The trials of collagen products make a broad case for your joints. In a 2024 review of 35 randomized trials with 3,165 people who had osteoarthritis, collagen products, gelatin among them, reduced pain and improved physical function compared with control groups, with no more side effects, and the reviewers rated the function result high certainty and the pain result moderate.29

    Active people with sore joints have been studied too. In a 24-week placebo-controlled trial of 147 college athletes with joint pain from training (97 were analyzed), 10 grams of collagen hydrolysate a day in a drink lowered joint pain when walking by 1.11 points, against 0.46 with placebo. The difference was larger in the athletes with knee pain.35 Our guide to collagen for joints covers the supplement side. In your own pot, simmering chicken feet, necks and knuckles along with the bones is the simplest way to fill your broth with those joint-building materials.

    3

    Firmer, better-hydrated skin

    Emerging evidenceHuman studyPooled analyses of 26 and 23 placebo-controlled trials (collagen supplements)

    Collagen gives your skin its firmness. Bone broth's proline is crucial for skin repair, and its glycine improves your sleep and liver detoxification, both of which matter for skin that ages well.2 Across 26 placebo-controlled trials with 1,721 people, mostly women, hydrolyzed collagen improved skin hydration and elasticity more than placebo, whether it came from fish or another source.30 A 2025 review of 23 trials (1,474 people) found the same gains in hydration, elasticity and wrinkles overall, though not in the trials without industry funding.36

    Chicken broth brings something extra for your skin, too: hyaluronic acid, the molecule that holds water in your skin and declines with age.2037

    4

    May help you sleep more soundly

    Emerging evidenceHuman studyPlacebo-controlled glycine studies (3 g) · trial of 13 men, each tried both (15 g collagen peptides) · rat studies

    For better sleep, I suggest bone broth in the evening, chicken or beef, because its glycine calms the body.7 Glycine helps your body cool down for the night, and a falling core temperature is part of how sleep begins. In rats, oral glycine lowered core body temperature by sending more blood to the skin, and it acted on the brain's master clock.3831

    In people, the same research team's trials found that glycine before bed improved how well poor sleepers said they slept,38 and in their small trial in which 7 healthy men each tried glycine and a placebo while their sleep was cut by a quarter for three nights, 3 grams at bedtime eased next-day fatigue.39 A glycine-rich collagen drink did something similar for 13 athletic men with sleep complaints, who each tried it and a placebo: 15 grams of collagen peptides an hour before bed for 7 nights meant fewer awakenings on an overnight sleep study, 21.3 against 29.3 with placebo, though total sleep time didn't change.5 A warm mug an hour or so before bed fits right into a wind-down routine, alongside the other natural sleep aids that help.

    Fewer awakenings with a glycine-rich collagen drink before bed

    Fewer awakenings with a glycine-rich collagen drink before bed13 athletic men with sleep complaints · 15 g of collagen peptides or placebo 1 hour before bed for 7 nights · each man tried both. Collagen peptides, 15 g: 21.3 awakenings on night 7; Placebo: 29.3 awakenings on night 713 athletic men with sleep complaints · 15 g of collagenpeptides or placebo 1 hour before bed for 7 nights · eachman tried both
    21.3 awakenings on night 7
    COLLAGEN PEPTIDES, 15 G
    29.3 awakenings on night 7
    PLACEBO
    Source: Thomas et al. · European Journal of Nutrition, 2024 [5]Awakenings counted by an overnight sleep study on the seventh night.
    One thing you can do is drink bone broth before bed. Bone broth and collagen are high in the amino acid glycine, which helps lower your core body temperature, improves deep sleep quality and calms the nervous system.Dr. Josh Axe, DC, DNM, CNSFrom Why SLEEP is Medicine: My 4 Tips to Improve Energy, The Dr. Josh Axe Show (2026), at 39:32
    5

    Sick-day support for colds

    Emerging evidenceHuman studyStudy of 15 adults, each tried every drink · lab study of white blood cells

    When I do get sick, I eat chicken broth or chicken vegetable soup for every meal, breakfast, lunch and dinner, for four or five days straight.40 My mom gave me chicken noodle soup when I was sick as a kid. The ancient Chinese remedy for a sick child is ginger tea with a chicken bone broth soup that's mostly broth, with a little vegetable and a little chicken.41

    Hot chicken soup gets the mucus in your nose moving. In a study of 15 healthy adults who each tried every drink, sipping hot chicken soup raised nasal mucus speed from 6.9 to 9.2 millimeters a minute five minutes later, against 6.2 to 8.4 for hot water. The researchers concluded that the soup seemed to carry something extra beyond its heat, and since the effect had faded by 30 minutes, keep the mugs coming.19 In a lab study, a traditional chicken soup slowed the migration of neutrophils, white blood cells that gather wherever there's inflammation, and the chicken and every vegetable in the pot had that activity on their own. The researchers suggested this mild anti-inflammatory effect may be one way soup eases a cold.18

    During cold-and-flu season, my immune soup in the recipes below is the one to keep on the stove, alongside the other natural cold remedies that help you recover.

    6

    Rehydrates you better than plain water

    Moderate evidenceHuman studyRandomized study of 30 adults, each tried all four drinks · trial of 13 men, each tried both

    Broth is water with sodium and potassium already in it, and that helps your body hold on to the fluid you drink. In a randomized study, 30 adults (15 men and 15 women) each tried all four drinks after losing 2.5% of their body weight. With two 175-milliliter servings of a salted chicken broth (about 6 ounces each) followed by water, plasma volume came back to within 1.6% of where it started, against a 5.6% shortfall with water alone and 4.2% with a sports drink. People also passed less of it as urine than with the sports drink (188 against 310 milliliters).4 That makes a mug of broth a smart drink on a sick day, after a sweaty workout or while you're replacing electrolytes during the keto flu.

    Chicken broth may even help you perform. In a trial of 13 trained men who each tried both, about 607 milliliters of a chicken broth made from chicken meat, taken 40 minutes before an 8-minute cycling time trial, raised average power 5.2% over a taste-matched placebo soup, 5.0 against 4.75 watts per kilogram of body weight.42

    More cycling power after chicken broth

    More cycling power after chicken broth13 trained men · chicken broth made from chicken meat or a taste-matched placebo soup, 40 minutes before an 8-minute time trial · each man tried both. Chicken broth: 5 watts per kg, average power; Placebo soup: 4.75 watts per kg, average power13 trained men · chicken broth made from chicken meat or ataste-matched placebo soup, 40 minutes before an 8-minutetime trial · each man tried both
    5 watts per kg, average power
    CHICKEN BROTH
    4.75 watts per kg, average power
    PLACEBO SOUP
    Source: Barbaresi et al. · Journal of the International Society of Sports Nutrition, 2021 [42]Average power during the time trial was 5.2% higher with the chicken broth.

    Bone broth in Chinese medicine

    Long before anyone measured glycine, Traditional Chinese Medicine treated broth as a food that warms you and builds you back up. Its guidance for a struggling gut is written right into the Healing Leaky Gut Protocol: "A healing gut prefers warm, cooked, soft foods over raw, cold, or fibrous ones."3

    Broth also nourishes your deeper reserves in Chinese medicine terms. On my show, I've described it this way: "Bone broth is very nourishing to the adrenals and the kidneys."43 When your thyroid is low, Chinese medicine says to warm your body, so I recommend drinking both chicken and beef bone broth and making soups your most common meal.43

    Chinese medicine also has a rule of thumb for colds and other viruses: eat a lot of light yellow foods, such as garlic, onion, chicken broth and miso soup, which tend to be immune-activating.4441 A golden chicken broth with garlic, onion, ginger and a spoonful of miso is that idea in a single bowl, and it's the base of the immune soup below.

    How to make bone broth at home

    Making bone broth takes a few minutes of work and a long, slow simmer, and the bones you choose matter more than anything else. For chicken, use necks, feet, wings or the carcass from a roast chicken, ideally from pasture-raised birds. For beef, use a mix of knucklebones, marrow bones and oxtail, ideally from grass-fed cattle. The feet, necks and knuckles count most, because their cartilage and connective tissue are what give a broth its gel.

    Beef and lamb bones taste best blanched and roasted first, while chicken and fish bones can go straight into the pot. Add carrots, celery, onion and garlic (the peels can stay on), bay leaves, peppercorns and fresh herbs, then cover everything with cold filtered water and add a splash of apple cider vinegar. Vinegar earns its place in the pot, because in lab tests, acidifying a bone broth raised the calcium and magnesium drawn out of the bones 17.4- and 15.3-fold, and simmering longer than 8 hours drew out more still.24

    Keep the pot at a bare simmer, chicken for 24 to 48 hours and beef for 24 to 36, skimming off the foam and fat that rise and adding water so the bones stay covered. Then strain it into shallow containers and refrigerate it promptly, and the fat will harden on top so you can lift it off. A broth that sets like jelly in the fridge tells you it's full of gelatin. Homemade broth keeps 3 to 4 days in the refrigerator and 2 to 3 months in the freezer, the federal food safety guidance for soups and stews.45 Freeze what you won't use in a few days in jars or ice-cube trays.

    Recipe
    Total24 to 48 hours
    YieldAbout 20 cups

    Ingredients

    • 4 pounds chicken necks, feet and wings, or the bones and carcass of a whole chicken (no meat)
    • 3 carrots, chopped
    • 3 celery stalks, chopped
    • 2 medium onions, peel on, quartered
    • 4 garlic cloves, peel on and smashed
    • 3 tablespoons apple cider vinegar
    • 2 bay leaves
    • 3 sprigs fresh thyme
    • 5 to 6 sprigs parsley
    • 1 teaspoon dried oregano
    • 1 teaspoon whole peppercorns
    • 1 teaspoon sea salt
    • Cold filtered water to cover

    Instructions

    1. Put everything in a 10-quart slow cooker or a large stockpot and add water to cover.
    2. Bring to a gentle simmer and cook for 24 to 48 hours, skimming off foam and fat now and then and adding water so the bones stay submerged.
    3. Let it cool slightly, strain it through a colander into a bowl and discard the solids.
    4. Pour it into shallow containers, cover and refrigerate it promptly, then lift off the fat that hardens on top.
    5. Refrigerate for up to 3 to 4 days, or freeze for 2 to 3 months.
    Recipe
    Total24 to 36 hours
    YieldAbout 20 cups

    Ingredients

    • 5 pounds beef bones (knucklebones, marrow bones and oxtail), ideally from grass-fed cattle
    • 4 carrots, chopped
    • 4 celery stalks, chopped
    • 2 medium onions, peel on, quartered
    • 4 garlic cloves, peel on and smashed
    • ¼ cup apple cider vinegar
    • 2 bay leaves
    • 3 sprigs fresh thyme
    • 6 sprigs parsley
    • 1 teaspoon whole peppercorns
    • ½ teaspoon sea salt
    • Cold filtered water to cover

    Instructions

    1. Heat the oven to 450 degrees F. Cover the bones with cold water in a large pot, bring to a boil, simmer for 20 minutes, then drain and rinse them.
    2. Spread the bones and vegetables in a roasting pan without piling them up, roast for 30 minutes, turn them and roast for 20 minutes more.
    3. Move everything to a 10-quart slow cooker or stockpot, add the vinegar, herbs, peppercorns and salt, and cover with cold water by about an inch.
    4. Simmer on low for 24 to 36 hours, skimming the fat that rises now and then.
    5. Strain into shallow containers, cover and chill promptly, then lift off the hardened fat. Refrigerate for up to 3 to 4 days, or freeze for 2 to 3 months.

    Pressure cooker or slow cooker?

    A slow cooker is the easiest way to hold a pot at a gentle simmer for a day or two, and both recipes above fit a 10-quart cooker on low. An electric pressure cooker gets you a lighter broth in an hour or two, and it's the version I suggest for people who are sensitive to histamine, as the safety section below explains.8 For more ways to cook it, see our collection of bone broth recipes.

    How much bone broth should you drink a day?

    Quick answer

    I recommend about a cup (8 ounces) of bone broth most days, and 8 to 16 ounces a day, ideally 16, while you're healing your gut.63 A cup a day is also the amount in my Anti-Inflammatory Reset and in my protocol for small intestinal bacterial overgrowth, where it's gentle enough for a sensitive gut.1213

    In the Healing Leaky Gut Protocol, you start in the Replace step by sipping 8 to 16 ounces a day, warm, between meals, and you continue daily in the Repair step, ideally 16 ounces.3 For everyday health, the Mitochondrial Longevity Protocol keeps it at 8 ounces most days.6 Every single day, I recommend either drinking bone broth or having collagen, whether that's a supplement or a protein that contains it.2 Our guide to how much bone broth to drink a day walks through the amounts for different goals.

    How much collagen a mug delivers depends on the pot. In a lab analysis of commercial and homemade bone broths, amino acid levels varied widely from recipe to recipe, with café-made broths running highest and homemade broths ahead of store-bought ones. A broth made to one standard recipe carried less glycine, proline and hydroxyproline than the 20-gram dose of collagen used in research.46 So on the days you want more, stir a spoonful of bovine or fish gelatin or a scoop of collagen into your mug. Gelatin has been tested that way: in a study of 8 men who each tried all three drinks, 15 grams of gelatin with vitamin C an hour before exercise raised a blood marker of collagen building 153%, against 53.9% with a placebo drink.47

    Timing is flexible. Between meals works well while you're healing your gut, and a warm cup or a warm breakfast smoothie is a gentle way to start the day. The evening is the time to drink it if better sleep is your goal.387

    How to use bone broth: recipes and ideas

    The simplest way to use bone broth is to sip it warm from a mug with a pinch of sea salt. Once you have a pot in the fridge, it finds its way into almost everything you cook.

    Sip it. Warm a cup with a pinch of sea salt, a little grated ginger or a squeeze of lemon, between meals or in the evening.
    Cook grains in it. Use broth in place of water for rice, quinoa or millet.
    Sauté and braise. Splash it into sautéed greens or use it as the liquid for braised root vegetables.
    Make soup. Build chicken vegetable soup, Thai coconut chicken soup or a beef bone and root vegetable soup on it.
    Warm breakfast. Blend a scoop of bone broth protein into a warm sweet potato smoothie (recipe below).
    A short fast. Drink only broth and herbal tea for a short stretch; our bone broth fast guide shows how.

    That last idea comes straight from my own practice, because when I started writing about bone broth, I started having patients do a bone broth fast, where they would just drink bone broth and herbal tea and do a form of intermittent fasting with it, and the results people saw were fantastic.11

    For a gut-repair week, the base of your diet should be soups. Think of a classic chicken vegetable soup with a few tweaks: organic chicken, bone broth, celery and carrots, a little grated ginger and a pinch of sea salt, plus onions if you do okay with them (skip them if you have SIBO).8

    When I'm sick, I make an immune soup with chicken bone broth, chicken, carrots, celery, onion and garlic. I grate in ginger and add thyme, oregano, sage and a big tablespoon of yellow miso,40 and I'd throw mushrooms in there too.44 Here it is with amounts.

    Recipe
    Total45 minutes
    Yield6 servings

    Ingredients

    • 8 cups chicken bone broth
    • 1 pound organic chicken breast or thighs, cut into bite-size pieces
    • 2 carrots, sliced
    • 2 celery stalks, sliced
    • 1 onion, diced
    • 4 garlic cloves, minced
    • 1 tablespoon grated fresh ginger
    • 1 cup sliced mushrooms (optional)
    • 1 teaspoon each dried thyme, oregano and sage
    • 1 heaping tablespoon yellow miso
    • Sea salt, to taste

    Instructions

    1. Bring the broth to a simmer in a large pot, add the chicken and cook for 15 minutes.
    2. Add the carrots, celery, onion, garlic, ginger, mushrooms and herbs and simmer until the vegetables are tender, about 20 minutes.
    3. Turn off the heat, whisk the miso into a ladle of the hot broth until smooth, stir it back into the pot and season with sea salt.

    After a holiday feast, my advice is simple: "For a few days, go easy on the sweets. Focus on more soups, a lot of bone broth, a lot of vegetables and a lot of berries after going higher in carbs and higher in fat during the holidays."48 The turkey carcass from a holiday dinner makes a rich broth for exactly that week, and our leftover turkey recipes help with the rest of the bird.

    Recipe
    Total24 hours
    YieldAbout 12 cups

    Ingredients

    • 1 roasted turkey carcass, broken into pieces, plus the neck and wing tips if you have them
    • 2 carrots, chopped
    • 2 celery stalks, chopped
    • 1 onion, peel on, quartered
    • 2 tablespoons apple cider vinegar
    • 2 bay leaves
    • A few sprigs fresh thyme and sage
    • Cold filtered water to cover

    Instructions

    1. Put the carcass pieces, vegetables, vinegar and herbs in a large stockpot or slow cooker and cover with cold water.
    2. Bring to a gentle simmer and cook for about 24 hours, skimming now and then and adding water to keep the bones covered.
    3. Strain into shallow containers, chill promptly and lift off the fat. Refrigerate for up to 3 to 4 days, or freeze for 2 to 3 months.

    For a warm breakfast, rather than a frozen fruit smoothie in the morning, I have patients blend a sweet potato or pumpkin smoothie with a scoop of collagen or bone broth protein, about 20 grams, and drink it at room temperature or warm.8

    Recipe
    Total5 minutes
    Yield1 serving

    Ingredients

    • 1 cup cooked sweet potato or pumpkin
    • 1 cup warm water or coconut milk
    • 1 scoop (about 20 grams) bone broth protein or collagen powder
    • ½ teaspoon ground cinnamon
    • Pinch of sea salt

    Instructions

    1. Blend everything until smooth.
    2. Drink it warm or at room temperature.
    Questions about bone broth?

    Ask Dr. Axe AI. Answers are grounded in this library, with sources shown.

    Homemade vs. store-bought: how to choose the best bone broth

    Homemade is the gold standard, because you choose the bones, the water and the length of the simmer. When you buy bone broth, read the label the way you'd read a recipe.

    • Bones up top. Chicken bones, beef bones, chicken feet or fish frames should be named at the top of the ingredient list, right after the water.

    • A short list. Bones, water, vegetables, herbs, vinegar and salt are all a broth needs.

    • No stand-ins. Skip broths that lean on natural flavors, yeast extract, hydrolyzed protein or added MSG for their taste.

    • Good animals. Look for bones from pasture-raised or organic animals.

    • Sodium per cup. Compare it across cartons, or buy unsalted broth and season it yourself.

    • Protein per cup. A richer broth lists more protein, and a broth that gels in the fridge is full of gelatin.

    Our guide to the best bone broth sources goes deeper on shopping.

    Bone broth protein powder and other forms

    Bone broth also comes dried, as powdered broth you stir into hot water, as capsules, and as bone broth protein powder, which is broth concentrated into a protein supplement. A protein powder made from bone broth counts toward your protein for the day. In the warm breakfast I have patients with low thyroid make, a bone broth or collagen protein and a plant protein together get them to about 30 to 40 grams of protein.43 Read those labels the same way you'd read a carton: bones named as the source, no added flavors or fillers, and the protein per serving listed plainly.

    Bone broth side effects and who should go easy

    For most people, homemade bone broth is simply good food, and a few people do better making it a different way or choosing a different bone.

    Histamine sensitivity. Some people with histamine intolerance don't do well with bone broth, because a long cook or a lot of vinegar leaves more histamine in the pot. If that's you, make a short batch, an hour or two in a pressure cooker with no vinegar, or use a simple chicken stock. That sort of broth most everyone tolerates, even people with histamine trouble and SIBO.8

    Lead. Bones store lead, and in a small blinded test of three organic chicken broths, the broths carried several times the lead of the tap water they were made with, up to 9.5 micrograms per liter against 0.89.49 Broader testing is reassuring, though, since an analysis of animal bone broths found a few micrograms of lead per serving and judged the risk minimal, and UK government tests of beef stock found little lead moving out of the bone.2450 Make your broth with filtered water, since tap water was the main lead source in boiled potatoes in those same UK kitchen tests, and rotate your chicken, beef and fish broths.50 Vinegar raised lead only slightly, so keep the splash.24

    Allergies. Beef broth carries bovine gelatin, which can trigger alpha-gal (red meat) allergy. Of 40 people with red meat allergy in one study, 30 were also sensitized to gelatin, and alpha-gal was found in bovine gelatin.51 Fish broth can trigger fish allergy, and in one documented case, hydrolyzed fish collagen caused anaphylaxis.52 If either applies to you, make chicken or turkey broth instead.

    Sodium. USDA's records for homemade stock list 343 to 475 milligrams of sodium a cup.2321 If you're watching sodium for blood pressure, compare the per-cup sodium on store-bought labels, or make your own and salt it to taste.

    Kidney stones. Large added loads of gelatin raise oxalate in the urine. In a controlled-diet study of 10 healthy adults, 30 grams of gelatin a day for 5 days raised urinary oxalate 43% compared with whey protein, while 1 to 2 grams didn't.53 If you form calcium-oxalate kidney stones, enjoy your broth, keep added gelatin or collagen powders modest and drink plenty of water.

    Fasting. If you're pregnant or nursing, managing diabetes or another condition, taking daily medication or have any history of disordered eating, talk with your doctor before a broth-only fast, and choose the gentlest form, such as an overnight fast.54

    Interaction check: Low. Bone broth has no documented drug interactions, and if you're on a fluid limit for heart or kidney care, count your broth toward it.

    The bottom line

    Should you drink bone broth?

    Yes. Bone broth is one of the most healing foods you can make. Hours of simmering turn bones, cartilage and connective tissue into a warm, easy-to-digest food rich in gelatin, glycine, proline and glutamine, the building blocks your gut lining, joints and skin are made of. It's the number one food in my Healing Leaky Gut Protocol. In people, chicken broth has rehydrated better than water and hot chicken soup has sped up the flow of nasal mucus, and trials of the glycine and collagen it carries point to firmer skin, easier joints and fewer awakenings at night.

    Make it at home from pasture-raised chicken bones and feet or grass-fed beef bones with a splash of apple cider vinegar, and drink about a cup most days, more while you're healing your gut. Our ancestors never wasted the bones, and with a pot on the stove this week, you don't have to either.

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    Bone broth: frequently asked questions

    Is bone broth good for you?

    Yes. Bone broth carries gelatin, glycine, proline and glutamine from simmered bones and cartilage,1 and it's the number one food in Dr. Axe's Healing Leaky Gut Protocol.3 In a randomized study of 30 adults who each tried all four drinks, chicken broth restored blood plasma volume after dehydration better than water, leaving a 1.6% shortfall against 5.6%.4

    What's the difference between bone broth, broth and stock?

    Mostly cooking time and what goes in the pot. Broth is usually simmered from meat for an hour or two and stock from bones for a few hours, while bone broth simmers bones, joints and cartilage for a day or more, which pulls far more collagen out as gelatin.19 USDA's nutrition records are for home-prepared stock.23

    Does bone broth have collagen?

    Yes. Long simmering pulls collagen out of bones, skin and cartilage as gelatin, the cooked form of collagen, which is why a rich broth sets like jelly in the fridge, and it carries collagen's amino acids glycine, proline and hydroxyproline.19 Chicken broth also carries hyaluronic acid and chondroitin sulfate.20

    Is chicken broth as good as bone broth?

    Not quite, because the bones, feet and necks add collagen that a quick meat broth doesn't have, which makes chicken bone broth the best kind of chicken broth. Dr. Axe calls chicken broth in particular possibly the most beneficial broth, since along with collagen it carries glucosamine, chondroitin and hyaluronic acid.17 A quick broth made from chicken meat is still a good food: in a trial of 13 trained men who each tried both, chicken broth made from chicken breast raised cycling power 5.2% over a placebo soup.42

    What are the benefits of bone broth for women?

    Bone broth gives women the collagen-building amino acids that skin, joints and the gut lining use, and women tend to get less collagen from food. In a survey of 1,500 Irish adults, women ate 2.3 grams a day on average, against 4.0 grams for men.15 Across 26 placebo-controlled trials with 1,721 people, mostly women, hydrolyzed collagen improved skin hydration and elasticity.30 In Chinese medicine, beef bone broth is one of the blood-building foods for women, along with beets and dates.55

    Is bone broth good for men?

    Yes. Bone broth gives men protein for very few calories, 4.73 grams for 31 calories in a cup of homemade beef stock, plus the glycine and collagen building blocks that joints use under training.21 In a 24-week placebo-controlled trial of 147 college athletes with joint pain, 10 grams of collagen hydrolysate a day lowered joint pain when walking more than placebo.35 In a trial of 13 trained men who each tried both, chicken broth before exercise raised cycling power 5.2%.42

    When is the best time to drink bone broth?

    Any time works, and the best time depends on your goal. Sip it between meals while you're healing your gut, as the Healing Leaky Gut Protocol suggests,3 have it in the morning as a warm cup or a warm breakfast smoothie,8 and drink it in the evening if you want better sleep, since its glycine calms the body.7

    Is it good to drink bone broth before bed?

    Yes. A warm cup before bed is one of Dr. Axe's tips for better sleep, because bone broth is rich in glycine, which calms the nervous system and, in rat studies, lowered core body temperature, part of how sleep begins.3231 In a trial of 13 athletic men with sleep complaints who each tried both, 15 grams of glycine-rich collagen peptides an hour before bed for 7 nights meant fewer awakenings, 21.3 against 29.3 with placebo.5

    Can you drink bone broth every day?

    Yes. Dr. Axe recommends bone broth or collagen every single day,2 about a cup (8 ounces) most days in his Mitochondrial Longevity Protocol, and 8 to 16 ounces a day, ideally 16, while healing the gut.63

    Can bone broth help with weight loss?

    It can help. Bone broth is filling and light, 31 to 86 calories a cup in USDA's homemade stocks.2123 In a study of 60 adults who each tried all five conditions, eating soup before lunch cut total meal calories 20% (134 calories), whether it was broth with the vegetables on the side or a pureed soup.56 Dr. Axe has had patients do a bone broth fast with herbal tea and a form of intermittent fasting, and weight loss was among the results they saw.11

    Is bone broth keto-friendly?

    Yes. A cup of homemade beef stock has 2.88 grams of carbohydrate and chicken stock 8.47 grams in USDA's records.2123 Its sodium and potassium make it a natural fit when you're replacing electrolytes on a keto diet, which is why it's on our list of keto drinks.

    Is bone broth safe during pregnancy?

    Yes, as a food. Homemade bone broth is a nourishing food in pregnancy, and in some Asian cultures, soup made from chicken or other bones soaked in vinegar has traditionally been given during pregnancy and after birth.24 Make it from good bones, bring it to a full simmer, and keep it in the fridge no longer than 3 to 4 days.45

    How long does homemade bone broth last?

    Homemade bone broth keeps 3 to 4 days in the refrigerator and 2 to 3 months in the freezer, the federal food safety guidance for soups and stews.45 Freeze it in jars or ice-cube trays so you can thaw a cup at a time.

    Why didn't my bone broth gel?

    Usually the pot had too few cartilage-rich bones or too much water. Next time, add chicken feet, necks and wings or beef knucklebones, use just enough water to cover the bones, and keep it at a gentle simmer for a day or more. A broth that doesn't gel is still a nourishing food.

    Is bone broth protein powder as good as bone broth?

    It's a convenient form of the same food. Bone broth protein powder is broth concentrated into a protein supplement, and it counts toward your protein for the day; Dr. Axe has patients with low thyroid pair a bone broth or collagen protein with a plant protein to reach about 30 to 40 grams of protein at breakfast.43 Homemade broth gives you the whole food, warm, with its electrolytes and the vegetables and herbs simmered into it.

    Freshness & update log

    November 4, 2026 — Rewrote the page in full under Dr. Axe's byline. The previous version, "Bone Broth Benefits for Joints, Skin and Gut Health" (2024), described a University of Nebraska chicken soup study as an amino acid and digestion study (it tested whole soup on white blood cells in the lab), overstated the results of a Penn State collagen trial and a skin trial, cited a gelatin tannate cell study and a fibrosis blood marker as evidence for gelatin and collagen, called MSG a neurotoxin, said broth's minerals come in easily absorbed forms and act like chelators, counted "over 19" amino acids and an allergy and asthma benefit we couldn't source, tied glycine to muscle loss through a mouse injection study, kept homemade broth for a week, and carried first-person lines we couldn't trace. This version keeps and builds on what held up after we searched Dr. Axe's protocols, books and shows, the traditional record and the human research: the gut, now led by bone broth's place as the number one food in his Healing Leaky Gut Protocol, with a Mayo Clinic review, a glutamine trial and a mouse study; joints and skin, with pooled collagen trials; immune support, with the chicken soup studies described correctly and his sick-day soup; detox, as glycine's role in glutathione; electrolytes, with a rehydration study; weight, with a soup study and his patients' bone broth fast; easy digestion and keto; store-bought label reading; and the how-to, with the vinegar step now backed by lab data and storage corrected to 3 to 4 days. It adds sleep as a full benefit, Chinese medicine, how bone broth works in your body, a Dr. Axe Score (6.0), three charts, a step diagram, five recipes and one safety section, with 56 references.

    March 20, 2024 — Previous version published.

    References

    1. Axe J. Ancient Remedies. Little, Brown Spark; 2021. Chapter "Meals Are Medicine," p. 94 (bone broth).
    2. Axe J. The BIGGEST Causes of Fast-Aging Skin (How to Reverse Aging). The Dr. Josh Axe Show. 2025 ("one of the most healing foods of all time" at 12:06; chicken broth, proline and glycine at 24:52; every day at 25:09; Chinese medicine at 32:58; YouTube https://www.youtube.com/watch?v=tsTht-zHz-U&t=726s).
    3. Axe J. Healing Leaky Gut: The 30-Day Healing Protocol. DrAxe.com protocol. 2026 (p. 15, "Foods That Heal": "1 Bone broth Glycine, glutamine, collagen — the building blocks of new gut lining" and the TCM principle; Replace step, "Bone broth daily — sip warm between meals, 8–16 oz"; Repair step, "Bone broth — continue daily, ideally 16 oz" and "Bone broth — large daily intake").
    4. Ray ML, Bryan MW, Ruden TM, et al. Effect of sodium in a rehydration beverage when consumed as a fluid or meal. J Appl Physiol (1985). 1998;85(4):1329-36. doi:10.1152/jappl.1998.85.4.1329. PMID:9760324
    5. Thomas C, Kingshott RN, Allott KM, et al. Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active males with sleep complaints. Eur J Nutr. 2024;63(1):323-335. doi:10.1007/s00394-023-03267-w. PMID:37874350
    6. Axe J. The Mitochondrial Longevity Protocol. DrAxe.com protocol. 2026 (p. 21, 7-day meal plan and daily drinks: "Bone broth — 8 oz most days"; Phase 1 eat-freely list).
    7. Axe J. The Truth About Cortisol Face and The Exact Steps To Fix It. The Dr. Josh Axe Show. 2026 (bone broth in the evening for sleep at 34:31; YouTube https://www.youtube.com/watch?v=7xJRhK-04k8&t=2071s).
    8. Axe J. How to Heal Your Gut in 30 Days. The Dr. Josh Axe Show. 2025 ("number one food for most people is bone broth" at 46:21; histamine and the short pressure-cooker batch at 46:28; soups as the base of the repair phase and his gut-repair chicken vegetable soup at 47:44; the warm breakfast smoothie he has patients make at 58:38; YouTube https://www.youtube.com/watch?v=ehASjzDVW5Y&t=2781s).
    9. Shoulders MD, Raines RT. Collagen structure and stability. Annu Rev Biochem. 2009;78:929-58. doi:10.1146/annurev.biochem.77.032207.120833. PMID:19344236
    10. Axe J, Cole W. Heal Your Cells. Avery; 2026. ISBN 9798217181353 (collagen as nearly one-third of the body's protein while most people eat almost exclusively muscle meat; "Step 3. Rebuild the gut barrier": bone broth, collagen or gelatin for the tight junctions of the intestinal lining).
    11. Axe J, Petrucci K. The Real Reason Your Gut Won't Heal (And How Bone Broth Fixes It) | Dr. Kellyann Petrucci. The Dr. Josh Axe Show. 2026 (using bone broth with patients at 2:42; patients' bone broth fast at 5:13; YouTube https://www.youtube.com/watch?v=mitZMXMzRx4&t=162s).
    12. Axe J. The Anti-Inflammatory Reset: The 30-Day Healing Protocol. DrAxe.com protocol. 2026 (p. 22, daily foods table: "Bone broth · 1 cup daily · Glycine and collagen for the gut lining and joints").
    13. Axe J. The SIBO Protocol. DrAxe.com protocol. 2026 (p. 22, "Top 10 SIBO-friendly foods": bone broth, 1 cup daily).
    14. Ricard-Blum S. The collagen family. Cold Spring Harb Perspect Biol. 2011;3(1):a004978. doi:10.1101/cshperspect.a004978. PMID:21421911
    15. Nulty CD, Walton J, Erskine RM. Habitual Dietary Collagen Intake Is Lower in Females and Older Irish Adults Compared with Younger Males. J Nutr. 2025;155(5):1408-1416. doi:10.1016/j.tjnut.2025.03.002. PMID:40058700
    16. Meléndez-Hevia E, De Paz-Lugo P, Cornish-Bowden A, et al. A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. J Biosci. 2009;34(6):853-72. doi:10.1007/s12038-009-0100-9. PMID:20093739
    17. Axe J. 11 Supplements Every 40+ Adult Should Consider. The Dr. Josh Axe Show. 2026 (bone broth and chicken broth at 16:20-16:51; glycine at 17:21; YouTube https://www.youtube.com/watch?v=FNhI28uezc8&t=993s).
    18. Rennard BO, Ertl RF, Gossman GL, et al. Chicken soup inhibits neutrophil chemotaxis in vitro. Chest. 2000;118(4):1150-7. doi:10.1378/chest.118.4.1150. PMID:11035691
    19. Saketkhoo K, Januszkiewicz A, Sackner MA. Effects of drinking hot water, cold water, and chicken soup on nasal mucus velocity and nasal airflow resistance. Chest. 1978;74(4):408-10. doi:10.1378/chest.74.4.408. PMID:359266
    20. Seki Y, Ohkuma RC, Miyakawa Y, et al. Hyaluronan and chondroitin sulfate in chicken-vegetable bone broth delay osteoporosis progression. J Food Sci. 2024;89(3):1791-1803. doi:10.1111/1750-3841.16962. PMID:38317402
    21. U.S. Department of Agriculture, Agricultural Research Service. Soup, stock, beef, home-prepared (SR Legacy, FDC ID 172883; NDB 6170; 1 cup = 240 g). FoodData Central. Accessed November 4, 2026.
    22. U.S. Department of Agriculture, Agricultural Research Service. Soup, stock, fish, home-prepared (SR Legacy, FDC ID 172885; NDB 6174; 1 cup = 233 g). FoodData Central. Accessed November 4, 2026.
    23. U.S. Department of Agriculture, Agricultural Research Service. Soup, stock, chicken, home-prepared (SR Legacy, FDC ID 172884; NDB 6172; 1 cup = 240 g). FoodData Central. Accessed November 4, 2026.
    24. Hsu DJ, Lee CW, Tsai WC, et al. Essential and toxic metals in animal bone broths. Food Nutr Res. 2017;61(1):1347478. doi:10.1080/16546628.2017.1347478. PMID:28804437
    25. Matar A, Abdelnaem N, Camilleri M. Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Disease. Dig Dis Sci. 2025;70(6):1951-1961. doi:10.1007/s10620-025-08997-x. PMID:40180691
    26. Axe J. Complete Guide to Healing Leaky Gut Naturally. The Dr. Josh Axe Show. 2026 (bone broth, glycine, proline and hydroxyproline, "like supports like" at 33:05-33:35; YouTube https://www.youtube.com/watch?v=5Y4g5CgMDoU&t=1985s).
    27. McCarty MF, O'Keefe JH, DiNicolantonio JJ. Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection. Ochsner J. 2018;18(1):81-87. PMID:29559876
    28. Zhou Q, Verne ML, Fields JZ, et al. Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome. Gut. 2019;68(6):996-1002. doi:10.1136/gutjnl-2017-315136. PMID:30108163
    29. Liang CW, Cheng HY, Lee YH, et al. Efficacy and safety of collagen derivatives for osteoarthritis: A trial sequential meta-analysis. Osteoarthritis Cartilage. 2024;32(5):574-584. doi:10.1016/j.joca.2023.12.010. PMID:38218227
    30. Pu SY, Huang YL, Pu CM, et al. Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis. Nutrients. 2023;15(9). doi:10.3390/nu15092080. PMID:37432180
    31. Kawai N, Sakai N, Okuro M, et al. The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology. 2015;40(6):1405-16. doi:10.1038/npp.2014.326. PMID:25533534
    32. Axe J. Why SLEEP is Medicine: My 4 Tips to Improve Energy. The Dr. Josh Axe Show. 2026 (bone broth before bed and glycine at 39:32; YouTube https://www.youtube.com/watch?v=ZmTNCfQO8_g&t=2372s).
    33. Mar-Solís LM, Soto-Domínguez A, Rodríguez-Tovar LE, et al. Analysis of the Anti-Inflammatory Capacity of Bone Broth in a Murine Model of Ulcerative Colitis. Medicina (Kaunas). 2021;57(11). doi:10.3390/medicina57111138. PMID:34833355
    34. Taylor G, Leonard A, Tang JCY, et al. The effects of collagen peptides on exercise-induced gastrointestinal stress: a randomized, controlled trial. Eur J Nutr. 2023;62(2):1027-1039. doi:10.1007/s00394-022-03051-2. PMID:36370176
    35. Clark KL, Sebastianelli W, Flechsenhar KR, et al. 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin. 2008;24(5):1485-96. doi:10.1185/030079908x291967. PMID:18416885
    36. Myung SK, Park Y. Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Med. 2025;138(9):1264-1277. doi:10.1016/j.amjmed.2025.04.034. PMID:40324552
    37. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-8. doi:10.4161/derm.21923. PMID:23467280
    38. Bannai M, Kawai N. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. J Pharmacol Sci. 2012;118(2):145-8. doi:10.1254/jphs.11r04fm. PMID:22293292
    39. Bannai M, Kawai N, Ono K, et al. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol. 2012;3:61. doi:10.3389/fneur.2012.00061. PMID:22529837
    40. Axe J. How to Prevent & Heal Cold & Flu Naturally (Foods, Supplements, & Herbs for Rapid Recovery). The Dr. Josh Axe Show. 2024 (chicken broth for every meal when sick at 26:41; his immune soup recipe at 28:11; YouTube https://www.youtube.com/watch?v=jw-cciZ5TTY&t=1601s).
    41. Axe J. How to Boost Your Immune System Naturally | Q&A with Dr. Josh Axe. The Dr. Josh Axe Show. 2023 (light-yellow foods at 04:12; chicken bone broth, his mom and the ancient Chinese sick-day remedy at 16:47-17:23; YouTube https://www.youtube.com/watch?v=n9HNcZRXZbs&t=1017s).
    42. Barbaresi S, Blancquaert L, Nikolovski Z, et al. Ergogenic effect of pre-exercise chicken broth ingestion on a high-intensity cycling time-trial. J Int Soc Sports Nutr. 2021;18(1):15. doi:10.1186/s12970-021-00408-6. PMID:33588872
    43. Axe J. How to Heal Hypothyroidism and Hashimoto's Naturally. The Dr. Josh Axe Show. 2024 (warming the body with soups in Chinese medicine at 40:54; bone broth "very nourishing to the adrenals and the kidneys" at 41:23; the breakfast he has patients make, with a bone broth or collagen protein for about 30 to 40 grams of protein, at 42:32; YouTube https://www.youtube.com/watch?v=OpI4SSyOQ6c&t=2483s).
    44. Axe J, Jockers D. The Natural Healing Swaps Doctors Rarely Talk About | Dr. David Jockers. The Dr. Josh Axe Show. 2026 (chicken soup and Chinese medicine light-yellow foods at 29:17, his immune soup at 29:57; YouTube https://www.youtube.com/watch?v=YFgUkzIL4ZU&t=1757s).
    45. FoodSafety.gov (U.S. Department of Health and Human Services). Cold Food Storage Chart: "Soups and stews, vegetable or meat added: refrigerator 3 to 4 days; freezer 2 to 3 months." Date last reviewed September 19, 2023. Accessed November 4, 2026 (Internet Archive capture of October 21, 2026).
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    48. Axe J. How to Boost Digestion & Detox After A Big Meal. The Dr. Josh Axe Show. 2024 (soups and bone broth after the holidays at 11:23; YouTube https://www.youtube.com/watch?v=HLvIwtwrkNA&t=683s).
    49. Monro JA, Leon R, Puri BK. The risk of lead contamination in bone broth diets. Med Hypotheses. 2013;80(4):389-90. doi:10.1016/j.mehy.2012.12.026. PMID:23375414
    50. Baxter MJ, Burrell JA, Crews HM, et al. Lead contamination during domestic preparation and cooking of potatoes and leaching of bone-derived lead on roasting, marinading and boiling beef. Food Addit Contam. 1992;9(3):225-35. doi:10.1080/02652039209374066. PMID:1397397
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    52. Fujimoto W, Fukuda M, Yokooji T, et al. Anaphylaxis provoked by ingestion of hydrolyzed fish collagen probably induced by epicutaneous sensitization. Allergol Int. 2016;65(4):474-476. doi:10.1016/j.alit.2016.03.012. PMID:27569115
    53. Knight J, Jiang J, Assimos DG, et al. Hydroxyproline ingestion and urinary oxalate and glycolate excretion. Kidney Int. 2006;70(11):1929-34. doi:10.1038/sj.ki.5001906. PMID:17021603
    54. Axe J. The 7 Biblical Protocols for Healing. DrAxe.com protocol. 2026 (fasting guidance: "If you are pregnant or nursing, managing diabetes or another condition, taking daily medication, or have any history of disordered eating, talk with your doctor before fasting and choose the gentlest form").
    55. Axe J. Why Men and Women Shouldn't Eat the Same Way. The Dr. Josh Axe Show. 2025 (Chinese medicine blood-building foods for women, including beef bone broth).
    56. Flood JE, Rolls BJ. Soup preloads in a variety of forms reduce meal energy intake. Appetite. 2007;49(3):626-34. doi:10.1016/j.appet.2007.04.002. PMID:17574705
    Dr. Josh Axe

    Dr. Josh Axe, DC, DNM, CNS

    Doctor of Natural Medicine · Founder, DrAxe.com

    Dr. Axe is a certified doctor of natural medicine, clinical nutritionist, and multiple New York Times bestselling author. He has spent 20+ years in clinical practice helping people heal at the root cause and founded one of the most-visited natural-health platforms in the world.

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