Healthy Fats · Cooking Fats
Ghee: Benefits, Nutrition, Smoke Point & Ghee vs. Butter
What ghee is, what a tablespoon gives you, what the studies of ghee itself show, how it compares with butter, how to cook with it and make it at home, and who should keep it small.

Why this score?
Weighting: Evidence 30% · Antioxidant & Anti-Inflammatory 25% · Clinical Effectiveness 25% · Nutrient Density 20% (5.9×0.30 + 6.2×0.25 + 7.0×0.25 + 6.8×0.20 = 1.77 + 1.55 + 1.75 + 1.36 = 6.43, shown as 6.4).

Ghee is butter simmered until its water cooks off and its milk solids are strained away, leaving a golden, nutty fat that handles high heat and carries only a trace of lactose. One tablespoon (12.8 grams) has 112 calories and 12.7 grams of fat, most of it saturated fat, plus about 12% of the daily value for vitamin A.12
- Best uses: high-heat sautéing and roasting, Indian dishes and golden milk
- How much: small amounts when a recipe calls for it, with extra virgin olive oil as your everyday fat
- Lactose: 2.9 mg per 100 grams or less in lab tests, a trace next to butter3
- Heart: in a randomized trial of 63 healthy young adults, ghee raised HDL along with total cholesterol, so the ratio between them held steady4
- Keep it small with fatty liver disease or high ApoB, and with a milk allergy, let your allergist test it first
Melt a pound of butter and let it simmer, and it slowly changes in front of you: the water bubbles away, the milk solids sink and toast to a golden brown, and what you pour off is a clear, amber fat that smells of browned butter and warm nuts. That fat is ghee, the clarified butter at the heart of Indian kitchens and of Ayurvedic medicine, where it's the milk product the classic texts mention most for healing.5
Simmering butter down this way does three useful things. It leaves only a trace of milk sugar, it raises the smoke point so the fat holds up in a hot pan, and it concentrates butterfat's vitamin A while keeping its signature short-chain fat, butyric acid, the fuel for the cells lining your colon.3617
On my list of the top 10 cooking fats, ghee comes in at number four, right behind the three I use nearly every day: extra virgin olive oil, avocado oil and coconut oil.8 From a functional medicine view, it beats out tallow. It's rich in butyrate, and even people with lactose intolerance can usually enjoy it.83
Ghee is one of the richest dietary sources of butyric acid available today, which may support gut health and immunity.Dr. Josh Axe, DC, DNM, CNSFrom Cellular Health EXPERT: How to Build Bulletproof Cells for Energy, Detox & Longevity, The Dr. Josh Axe Show (2025), at 38:00
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Ghee is 99.5% fat and only 0.24% water by USDA's measure, while butter is about 16% water, which is a big reason ghee keeps so well.1910
Ghee carries so little milk sugar that it's permitted on the UK diet for galactosaemia, a rare inherited disorder that keeps the body from breaking down galactose, while butter isn't.3
In a lab study of ghee made three ways from the milk of two cattle breeds, the method changed the flavor compounds but not the fatty-acid makeup, while the breed did shift the fats.11
What is ghee?
Ghee is clarified butter that's simmered until its milk solids brown, then strained, leaving a golden fat that's 99.5% fat.121 Ghee is usually made from cow's milk butter, though the International Dairy Federation's definition also allows sheep and goat milk.13 It's soft and creamy at room temperature and melts clear when you warm it.
Making ghee concentrates the fat. Commercial ghee is made by heating milk fat to about 230°F to 248°F (110°C to 120°C) for 10 to 20 minutes, and its rich flavor comes from the proteins, milk sugar and fat that change with that heat.10 What remains is nearly pure butterfat, with only 0.28 grams of protein and no measurable carbohydrate per 100 grams.1
What's the difference between ghee and clarified butter?
Ghee is clarified butter taken one step further. In The Biblio Diet, Jordan Rubin and I describe it this way: heat butter to remove the milk solids and water and you get clarified butter, and simmer it longer and you get ghee, with a rich, nutty flavor and a higher smoke point.12 The longer simmer browns the milk solids before they're strained out, and that browning is where ghee's toasted flavor comes from.1014 As we wrote in the book, "Ghee, a member of the butter family, is a fantastic addition to your diet, offering incredible health benefits and a delicious, nutty flavor that enhances any dish." It's one of the healthy fats we recommend along with grass-fed butter and extra virgin olive oil.12
A short history of ghee
Ghee is woven into both the cuisine and the traditional medicine of India. A 2024 review of 11 Ayurvedic texts spanning more than 3,000 years counted 2,913 mentions of milk products used for healing, and ghee had 774 of them, more than any other milk product.5 Those texts gave ghee its biggest roles in the mind, digestion and nourishment, while modern research has mostly studied it for heart health, wound healing and skin.5
One of the best-known Ayurvedic preparations is golden milk, which combines turmeric with ginger, warming spices like black pepper, and ghee. As I've said on my show, the ghee and the warming spices help your body absorb nutrients like the curcumin in turmeric.8 Ghee traditions reach well beyond India, too. In the Kermanshah region of western Iran, the local ghee is traditionally made from fermented yogurt.13
Ghee nutrition facts
One tablespoon (12.8 grams) of ghee has 112 calories and 12.7 grams of fat: 7.9 grams saturated, 3.7 grams monounsaturated and 0.5 gram polyunsaturated. It supplies 108 mcg of vitamin A, about 12% of the daily value, plus small amounts of vitamin E and vitamin K1, and essentially no protein or carbohydrate.12
Ghee per 1 tablespoon (12.8 g) and per 100 g. Source: USDA FoodData Central, FDC ID 173412 (anhydrous butter oil, the clarified butterfat ghee is made of); per-tablespoon values calculated at USDA's 12.8-gram tablespoon; % Daily Value uses FDA reference values.12
| Nutrient | 1 tablespoon (12.8 g) | % Daily Value | Per 100 g |
|---|---|---|---|
Calories | 112 | n/a | 876 |
Total fat | 12.7 g | 16% | 99.5 g |
Saturated fat | 7.9 g | 40% | 61.9 g |
3.7 g | n/a | 28.7 g | |
0.5 g | n/a | 3.69 g | |
Butyric acid | 0.41 g | n/a | 3.23 g |
Cholesterol | 33 mg | 11% | 256 mg |
Vitamin A | 108 mcg RAE | 12% | 840 mcg RAE |
Vitamin E | 0.36 mg | 2% | 2.8 mg |
Vitamin K1 | 1.1 mcg | 1% | 8.6 mcg |
2.9 mg | <1% | 22.3 mg | |
Protein | 0.04 g | <1% | 0.28 g |
Carbohydrate | 0 g | 0% | 0 g |
That vitamin A is almost all retinol, 105 of the 108 mcg in a tablespoon, with a little beta-carotene besides.1
Ghee's most distinctive fat is butyric acid. Milk fat holds about 400 different fatty acids, which makes it the most complex natural fat, and almost half of its short-chain fat is butyric acid.15 USDA lists 3.23 grams of butyric acid per 100 grams of ghee, about 0.41 gram per tablespoon. Butter carries the same 3.23 grams per 100 grams, coconut oil has 0.009 gram, and USDA lists 0 for beef tallow and olive oil.19161718
Butyric acid comes from butterfat
What is ghee good for?
Ghee is best supported as a heat-stable cooking fat that's practically free of lactose and supplies vitamin A and butyric acid.13 In a randomized trial of 63 healthy young adults, it raised HDL along with total cholesterol.4 Research on vitamin K2, which dairy fat carries, points to heart and artery benefits, and ghee has a 3,000-year record in Ayurvedic medicine.195
Where the research stands: ghee has been studied in people in the four controlled trials reported here, with 24 to 110 adults over 4 to 12 weeks, in one 6-week study of 60 adults with no comparison group, and in two population surveys that compared people who eat more ghee with people who eat less.2042122232413 The vitamin, lactose and butyric acid findings come from lab analyses of the fat itself.13
| Benefit | Evidence | What was studied | What it shows |
|---|---|---|---|
Vitamin A | Strong, for composition | Anhydrous butterfat (ghee) | 108 mcg per tablespoon, about 12% DV, almost all preformed retinol1 |
Practically lactose-free | Moderate | 5 ghee samples vs. 2 butter samples | 2.9 mg of lactose per 100 g or less in ghee vs. 685 to 688 mg in butter3 |
Cholesterol in healthy adults | Mixed | Ghee in place of mustard oil or olive oil, or added to the usual diet | HDL rose with total cholesterol; no significant change in a smaller 8-week trial; LDL fell in a 6-week study with no comparison group; apoB higher than on olive oil4212320 |
Vitamin K2 for bones and arteries | Emerging | Dietary vitamin K2 from all foods; K2 in dairy fat | 57% lower risk of dying of heart disease with the most K2 in 4,807 adults19 |
Butyric acid | Emerging | Butterfat's own butyric acid; butyrate made in the colon | 3.23 g per 100 g of ghee; butyrate fuels colon cells and calmed inflammation in lab and animal studies17 |
High-heat cooking | Preclinical (lab and composition) | Ghee's fat profile and smoke point | |
Ayurvedic food and medicine | Traditional | Ghee in Ayurveda | 774 therapeutic mentions, the most of any milk product5 |
How ghee works in your body
Most of what ghee does traces to what's concentrated in it once the water and milk solids are gone: butterfat's short-chain fatty acids, led by butyric acid, and its fat-soluble vitamins. Of those vitamins, vitamin K2 has one of the best-mapped jobs in the body. Here's how it steers calcium, step by step.
The K2 forms of vitamin K come mainly from foods such as butter, cheese, egg yolk and natto, while K1 comes mostly from green vegetables.25
Vitamin K activates a family of proteins by attaching the chemical groups they need to hold on to calcium, a step called carboxylation.26
One of those proteins, osteocalcin, once activated, helps lay calcium down in the bone matrix.26
Another, matrix Gla protein, protects blood vessels and may help keep calcium from building up in the vessel wall.26
In a study that measured diet and coronary calcification at one point in time in 564 postmenopausal women, those who ate the most K2 had 20% lower risk of coronary calcification than those who ate the least, while K1 intake showed no significant link.27
Ghee benefits, ranked by evidence
Ordered by how strong the research is, ghee's benefits begin with vitamin A and a near-absence of lactose, then its effects on cholesterol in healthy adults, vitamin K2, butyric acid, its stability under heat and its long place in Ayurveda.
A natural source of vitamin A
Strong evidence (composition)In vitro (lab)USDA composition recordA tablespoon of ghee carries 108 mcg of vitamin A, about 12% of the daily value, almost all of it preformed retinol, the form your body can use as it is.12 With the water gone, a tablespoon of ghee holds a little more than a tablespoon of butter, which carries 97 mcg.9
Study takeaway: a tablespoon of ghee supplies about 12% of the daily value for vitamin A.
Practically free of lactose
Moderate evidence (lab analysis)In vitro (lab)Lab analysis · 5 ghee and 2 butter samplesIn a UK lab analysis, ghee carried 2.9 mg of lactose per 100 grams or less, a trace next to the roughly 685 mg in butter.3
Study takeaway: ghee carried no more than 2.9 mg of lactose per 100 grams in lab tests.
Cholesterol in healthy adults
Mixed evidenceHuman studyRandomized · 63 adults · 8 weeks; 6-week study, no comparison group · 60 adultsIn a randomized trial of 63 healthy young adults in India, getting 10% of calories from ghee for 8 weeks raised total cholesterol, and HDL rose along with it, so the ratio of total cholesterol to HDL didn't change significantly.4 In a 6-week study with no comparison group, LDL fell in 40 of 60 healthy adults who added ghee to their usual diet.23 The heart section below has every result, including a 4-week comparison with olive oil.20
Study takeaway: in healthy young adults, ghee raised HDL along with total cholesterol, leaving their ratio steady.
Vitamin K2 for bones and arteries
Emerging evidenceHuman studyPopulation study · 4,807 adults; dairy composition analysesAs I've said on my show, ghee is one of the best food sources of vitamin K2, which helps direct calcium to your bones instead of your arteries.8 K2 travels with dairy fat: butter is a recognized source, and in a lab analysis of U.S. dairy foods by Tufts and USDA researchers, vitamin K, mostly K2, rose with the fat, reaching 587 mcg per 100 grams in heavy cream.2528 USDA's record for ghee lists only vitamin K1, so it gives no K2 figure for ghee itself.1 What K2 does is better known: in a population study that followed 4,807 Dutch adults, those who ate the most K2 had 57% lower risk of dying of heart disease, 26% lower risk of dying of any cause and 52% lower odds of severe calcium buildup in the aorta than those who ate the least.19
Study takeaway: people who ate the most vitamin K2 had less calcium buildup in the aorta and fewer deaths from heart disease.
Rich in butyric acid
Emerging evidenceIn vitro (lab)USDA composition records; reviews of butyrate in the colonGhee carries 3.23 grams of butyric acid per 100 grams, the same as butter, while olive oil and tallow carry none.191817 In your colon, butyrate is a main energy source for the cells lining the gut, and in lab and animal studies it calmed inflammation and strengthened the gut barrier; most of that work looked at the butyrate your gut bacteria make from fiber.7 Cooking fiber-rich vegetables in a little ghee puts both sources on your plate.
Study takeaway: ghee carries 3.23 grams of butyric acid per 100 grams, the same as butter and far more than olive oil, coconut oil or tallow.
A stable fat for high heat
Preclinical (lab and composition)In vitro (lab)USDA composition · Dr. Axe's showGhee is low in the fragile fats that break down under heat, and with its milk solids strained out, its smoke point runs about 485°F.18
Study takeaway: ghee is low in the fragile fats that break down under heat.
A pillar of Ayurvedic medicine
Traditional useTraditional useReview of 11 Ayurvedic textsGhee has the deepest roots of any milk product in Ayurveda, with 774 therapeutic mentions across 11 texts, grouped into 15 clusters of benefits.5
Study takeaway: Ayurvedic texts mention ghee for healing more than any other milk product.
Is ghee healthier than butter?
For cooking and for anyone sensitive to lactose, ghee has the edge: it's practically lactose-free, it takes higher heat, and with the water gone, each tablespoon carries a little more vitamin A.3619 Both are traditional fats on Dr. Axe's top-10 list, ghee at number four and grass-fed butter at number six, and both get about 62% of their fat from saturated fat.819
Ghee is butter with the water and milk solids taken out, so the two share the same butterfat. The biggest difference is milk sugar. A UK lab analysis for galactosaemia diets measured lactose in 12 samples: the 5 ghee samples carried from under 0.05 to 2.9 mg per 100 grams, while the 2 butter samples carried 685 to 688 mg.3
Ghee carries a trace of butter's lactose
| Per tablespoon | Ghee (12.8 g) | Unsalted butter (14.2 g) | Coconut oil (13.6 g) | Beef tallow (12.8 g) |
|---|---|---|---|---|
Calories | 1121 | 1029 | 12116 | 11517 |
Saturated fat | 7.9 g1 | 7.2 g9 | 11.2 g16 | 6.4 g17 |
Butyric acid (the short-chain fat) | 0.41 g1 | 0.46 g9 | 0.001 g16 | 0 g17 |
Vitamin A | 108 mcg RAE1 | 97 mcg RAE9 | 016 | 017 |
Lactose and milk protein (per 100 g) | None; not a dairy food16 | None; not a dairy food17 | ||
Smoke point | About 485°F8 | About 300°F to 350°F6 | About 350°F virgin, 400°F refined36 | No published measurement35 |
Best uses | High-heat sautéing, roasting and searing; Indian dishes and golden milk8 | Lower-heat cooking and finishing a dish, for its creamy flavor6 | Baking and stir-fries; refined for higher heat36 | Searing, roasting and sautéing, a spoonful or two at a time35 |
Dr. Axe's take | A healthy fat and number four on his top 10, but an occasional one in his own kitchen128 | Grass-fed is a healthy traditional fat, number six on his top 10128 | One of his top fats, used nearly every day; it raises ApoB compared with unsaturated oils836 | Good in small amounts and in moderation; not ideal for heart health, fatty liver disease or large amounts35 |
Gram for gram, ghee is the more concentrated fat, so a tablespoon carries slightly more calories and saturated fat than a tablespoon of butter.19 Most of what this page says about butterfat applies to grass-fed butter too. Reach for ghee for the hot pan or a lactose-sensitive gut, and for butter where you want its creamy flavor.
Against the two other traditional saturated fats, ghee is the one that brings butyric acid and vitamin A: USDA lists essentially none of either in coconut oil or beef tallow, while coconut oil carries the most saturated fat of the four, 11.2 grams per tablespoon.11617 Coconut oil sits in my top three and raises ApoB compared with unsaturated oils, so it's worth watching that number if you use it daily, and tallow is a fat I keep to small amounts.83635 And extra virgin olive oil stays the fat you can use most freely, every day.635
Is ghee good for your heart?
Used in moderation, ghee fits a heart-healthy diet: in a randomized trial of 63 healthy young adults, it raised total cholesterol and HDL together, so the ratio between them didn't change significantly.64 In a 4-week trial in which each of 30 healthy adults tried both fats, ghee raised apoB, the count of cholesterol-carrying particles, by about 9 mg/dL compared with refined olive oil.20 And in a 6-week study with no comparison group, LDL fell from 86.72 to 75.68 mg/dL in 60 healthy vegetarian adults who added 35 grams of ghee a day.23
Here's how I think about ghee and the other traditional animal fats. Ghee is more saturated, so it will nudge LDL up, but used in moderation as part of a whole-food diet, it's a reasonable, time-tested choice.6 Yes, you can have too much animal fat, and it can raise your risk of heart issues. That's why, as I said on my show, "My best piece of advice is olive oil: make it the fat you reach for first, every day."29 Long-term trials support that caution: in a Cochrane review, people who cut back on saturated fat for at least two years had 17% fewer combined cardiovascular events across 12 trials in 53,758 people, with little or no difference in deaths.30
The studies of ghee itself fill in the picture for healthy adults:
- In place of part of the cooking oil: At the All India Institute of Medical Sciences, 63 healthy, physically active young adults were randomly assigned to get 10% of their calories from ghee, with mustard oil for the rest of their added fat, or to use mustard oil alone, for 8 weeks. Total cholesterol rose in the ghee group, HDL rose along with it, and the ratio of total cholesterol to HDL didn't change significantly.4 An earlier 8-week trial by the same team, in 24 young adults, found no significant change in any blood fat in either group.21
- Against olive oil: In a randomized trial in Tehran, 30 healthy adults each spent 4 weeks with ghee and 4 weeks with refined olive oil as their main added fat, about 15% of their calories (30.6 grams a day on average), with a 2-week break between; they knew which fat they were eating, and all 30 finished. On ghee, apoB ran about 9 mg/dL higher and non-HDL cholesterol about 20 mg/dL higher than on olive oil, and LDL about 11 mg/dL higher, a difference that wasn't statistically significant. HDL, the cholesterol ratio, triglycerides, blood sugar, insulin, the clotting marker PAI-1, weight, waist and blood pressure didn't differ significantly, and a test meal made with either fat raised triglycerides, blood sugar and insulin about the same.20
- Added to the usual diet: In a 6-week study with no comparison group, 60 healthy vegetarian adults in India added 35 grams of ghee a day, about 2¾ tablespoons, to their usual diet. Total cholesterol fell from 154.37 to 140.83 mg/dL and LDL from 86.72 to 75.68 mg/dL, while triglycerides and HDL didn't change significantly; LDL fell in 40 of the 60 people. In the subgroup of 23 who started with high blood fats, LDL fell from 105.91 to 78.98 mg/dL, while the 37 with normal blood fats saw no significant change.23
LDL fell during 6 weeks of daily ghee
Population surveys of people who eat ghee regularly lean favorable. In a survey of 1,982 rural men in Rajasthan, India, those who ate at least 1 kilogram (about 2.2 pounds) of ghee a month had 77% lower odds of coronary heart disease than those who ate less, and the link held when the researchers accounted for other factors, though the higher-ghee men were also younger.24 In a survey of 5,550 adults in western Iran, who ate an average of 5.1 grams of traditional Kermanshah ghee a day, those in the top fifth for ghee had 30% lower odds of metabolic syndrome than those in the bottom fifth, with other differences between them taken into account.13 A 2010 paper that paired a rat study with a review of the earlier research concluded that the evidence doesn't support harm from moderate ghee intake in the general population, and it named the growing use of vanaspati, the hydrogenated vegetable fat sold as "vegetable ghee," among the factors that may be behind rising heart disease among Asian Indians.31
Keep an eye on ApoB. ApoB counts the particles that carry cholesterol, and it predicts heart risk better than LDL alone. Cook with ghee often and ApoB is the number to follow, and if yours is high or you have heart disease, let olive oil carry your cooking.
Three markers that show how your body handles fat
Targets are Dr. Axe's functional ranges.
- ApoB: The number of cholesterol-carrying particles in your blood. Dr. Axe's target is under about 80 mg/dL.
- Triglyceride-to-HDL ratio: A window on how you handle fat and sugar. Dr. Axe's target is under about 1.5, with both numbers in mg/dL.
- hs-CRP: Low-grade inflammation anywhere in the body. Dr. Axe's target is under 1.0 mg/L.
If fatty liver is a concern, add the liver enzymes ALT and GGT. These markers show how your body handles fat overall; they can't separate ghee's effect from the rest of your diet.
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Have results? Analyze them free →What is ghee's smoke point?
Ghee's smoke point is about 485°F, well above the 300°F to 350°F that Dr. Axe's cooking-oil chart gives butter, so it handles searing and roasting heat that would scorch butter.86 Smoke points are approximate, and they shift with refining and freshness.
A fat's smoke point is where it starts to smoke in the pan, and two things push ghee's higher. Clarifying strips out the milk solids and water, which is what lifts the smoke point; that means ghee can handle high cooking temperatures without breaking down into harmful compounds.12 And ghee is low in fragile fat: only 3.69 grams of every 100 are polyunsaturated, the type whose multiple double bonds heat breaks apart, while 61.9 grams are saturated fat, which holds steady.1
In my guide to seed oils, I list ghee with avocado oil and tallow as the steadiest choices for high-heat cooking, since all three resist oxidation better than polyunsaturated seed oils; tallow belongs in small amounts.6 That makes ghee a good match for sautéing, roasting and searing fish or vegetables.
How much ghee should you use?
Use ghee in small amounts, when a recipe calls for it, and make extra virgin olive oil the fat you use freely every day.6 There's no established daily amount, and a tablespoon brings 112 calories and 7.9 grams of saturated fat, 40% of the daily value.12
My everyday foundation is extra virgin olive oil, avocado oil for higher heat, and small amounts of grass-fed ghee, coconut oil or tallow when a recipe calls for it.6 So while I count ghee among the healthy fats,12 in my own kitchen it's an occasional one. As I said on my show, "I use ghee on occasion, maybe once a month."8 The last time, we steamed cauliflower and mashed it with ghee and plenty of sea salt in place of mashed potatoes.8
On that same show, I said not to go overboard with oils, even the good ones: most of your fat should come from whole foods, such as walnuts, wild-caught salmon and pastured eggs.8
Ask Dr. Axe AI. Answers are grounded in this library, with sources shown.
How to cook with ghee
Use ghee wherever you want butter's flavor at a heat butter can't take: sautéing, roasting, searing and the spice-warming step at the start of many Indian dishes.
How to make, buy and store ghee
Making it at home. Ghee takes one ingredient and about half an hour:
- Start with 1 pound of unsalted butter, grass-fed if you can find it.
- Melt it in a heavy, wide pan over medium-low heat. It will foam and sputter as the water cooks off.
- Keep it at a gentle simmer, skimming off the foam now and then, for about 20 to 30 minutes, as the milk solids sink and turn golden brown.
- When the sputtering stops and the fat is clear and golden, take it off the heat before the solids darken past golden brown.
- Pour it through cheesecloth set in a fine strainer into a clean, dry glass jar, and let it cool.
That browning is worth the wait. In a lab study, ghee made at medium to high temperatures, 248°F to 320°F (120°C to 160°C), browned more and showed stronger free-radical-scavenging activity, an antioxidant measure, and reheating it later didn't change either one.14 Hot butterfat burns, so use a back burner and keep children clear of the pot.
On the label. Look for ghee made from grass-fed or pasture-raised butter: pasture feeding raises the omega-3 fats, vaccenic acid and conjugated linoleic acid (CLA) in cow's milk.32 The ingredient list should name only butter, cream or butterfat. Skip anything sold as "vegetable ghee," a hydrogenated vegetable fat that borrows the name; the FAQ below covers it.
Storage. Because ghee is almost pure fat with so little water, it keeps well; what slowly limits its shelf life is oxidation of its unsaturated fats.10 Keep the jar sealed and away from light and the heat of the stove, dip in with a clean, dry spoon, and refrigerate it if you'll take a long time to finish it. Throw it out if it smells sour or sharp.
Ghee side effects and who should be careful
Ghee is a food fat with no documented medication interactions in cooking amounts, and most people do well with it. Keep it small with fatty liver disease, high ApoB or heart disease, and with a milk allergy, add it only after your allergist tests it.2233
Fatty liver disease
With fatty liver disease, make extra virgin olive oil your main fat and keep ghee small. In a 12-week randomized trial in Iran, adults with nonalcoholic fatty liver disease who habitually ate 3 to 8 servings of ghee a day (15 to 40 grams, about 1 to 3 tablespoons) either swapped that ghee for the same amount of rapeseed oil or kept eating ghee with healthy-diet advice, alongside their usual treatment; 110 finished, 55 in each group, after 10 dropped out, and the radiologist and lab staff didn't know who was in which group. Liver fat improved by at least one grade in 46 of the 55 people who swapped, against 15 of the 55 who kept their ghee, and the swap group's triglycerides, LDL, blood sugar, insulin and the liver enzyme ALT improved more, along with a weight loss of about 4.3 kilograms (9.5 pounds).22 In the group that kept its ghee, alkaline phosphatase, another liver enzyme, fell, while it rose slightly in the swap group.22
Milk allergy
Ghee is still a dairy food. Clarifying removes most of butter's protein, but a trace remains: USDA lists 0.28 grams of protein per 100 grams of ghee, against 0.85 grams in butter.19 In an allergy clinic in Rome, 30 children with IgE-mediated cow's milk allergy were skin-tested with clarified butter and, if the test was positive, offered a supervised food challenge; 25 then added clarified butter to their diets, and the other 5 chose not to.33 If you have a milk allergy, add ghee only after your allergist has tested you for it, and if you ever have throat swelling, hives or trouble breathing after eating it, get emergency care.
Blood thinners
Ghee carries little vitamin K1, about 1.1 mcg per tablespoon.1 If you take warfarin, the rule with any vitamin K food is to keep your intake steady from week to week rather than cutting it out; a systematic review of vitamin K intake and warfarin found that an effect on INR, the blood test that guides your warfarin dose, may show up only at intakes above about 150 mcg a day.34 Let the doctor who adjusts your warfarin know before any big change in how you eat.
The bottom line
Should you cook with ghee?
Yes. Ghee is butter simmered down to its golden, nutty fat: practically free of lactose, steady in a hot pan and rich in butyric acid, with vitamin A in every spoonful. It's number four on my list of the top 10 cooking fats, and when a recipe calls for something richer and more heat-stable than olive oil, it's a good one to reach for.
Ayurveda's long reliance on ghee is worth weighing too: those texts reflect generations of healers choosing it again and again for the mind, digestion and nourishment.
Buy it grass-fed or make it at home from a pound of good butter, use a little when a recipe calls for it, and keep extra virgin olive oil as the fat you use freely every day. Cook with traditional fats in their proper place, and every meal becomes a small way to support a body that was made to heal.
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Open the free protocol →Ghee: frequently asked questions
Is ghee healthy?
Yes, in small amounts for most people. Ghee is a heat-stable traditional fat that's practically free of lactose and supplies vitamin A and butyric acid, and in a randomized trial of 63 healthy young adults it raised HDL along with total cholesterol, so the ratio between them held steady.134 Dr. Axe ranks it fourth among cooking fats.8
What's the difference between ghee and clarified butter?
Ghee is clarified butter that's simmered longer: both start by heating butter to remove its water and milk solids, and ghee keeps cooking until the solids brown, which gives it a nutty flavor and a higher smoke point.12
Is ghee healthier than butter?
For high-heat cooking and for people sensitive to lactose, yes: ghee takes higher heat and carries only a trace of lactose, 2.9 mg per 100 grams or less against about 685 mg in butter.63 Both are mostly saturated butterfat, and Dr. Axe ranks ghee fourth on his list of cooking fats and grass-fed butter sixth.198
Is ghee better than coconut oil?
They do different jobs. Coconut oil is one of the three fats Dr. Axe uses nearly every day, while ghee is an occasional one in his kitchen; per tablespoon, ghee brings 0.41 gram of butyric acid and 108 mcg of vitamin A, which coconut oil essentially lacks, and coconut oil carries more saturated fat, 11.2 grams against 7.9.8116 Ghee also takes more heat, about 485°F against about 350°F for virgin coconut oil, and coconut oil raises ApoB compared with unsaturated oils.836
Is ghee better than beef tallow?
Dr. Axe ranks ghee fourth on his list of the top 10 cooking fats and grass-fed beef tallow seventh.8 By USDA's records, ghee carries butyric acid and vitamin A that tallow lacks, while tallow has no milk sugar or milk protein at all.117 His view of tallow is that it's good in small amounts and in moderation, but not ideal for heart health, fatty liver disease or large amounts.35
Is ghee OK if you're lactose intolerant?
Can you eat ghee if you have a milk allergy?
Is ghee dairy-free?
What is ghee's smoke point?
Does ghee have vitamin K2?
Is ghee a good source of butyrate?
Yes. Ghee carries 3.23 grams of butyric acid per 100 grams, about 0.41 gram per tablespoon, the same per 100 grams as butter, while USDA lists 0 for olive oil and beef tallow.191817 Cooking fiber-rich vegetables in a little ghee pairs its butyric acid with the fiber your gut bacteria turn into butyrate.7
Does ghee raise cholesterol?
It can raise total cholesterol, but in a randomized trial of 63 healthy young adults, HDL rose along with it, so the ratio of total cholesterol to HDL didn't change significantly.4 In a 4-week trial in which each of 30 adults tried both fats, ghee raised apoB by about 9 mg/dL compared with refined olive oil,20 while in a 6-week study with no comparison group, LDL fell in 40 of 60 healthy adults who added ghee to their usual diet.23
How much ghee should you eat a day?
Is ghee keto-friendly?
Is grass-fed ghee better?
Is ghee good for your skin?
Ayurveda has long used ghee on the skin, and skin health and wound healing are two of the areas modern research on ghee has focused on most.5
What can you substitute for ghee?
Use avocado oil for high-heat cooking, extra virgin olive oil for everyday cooking, and coconut oil or a small amount of tallow when a recipe wants a richer, more heat-stable fat; grass-fed butter works at lower heat.6
Does ghee need to be refrigerated?
Freshness & update log
October 9, 2026 — Trimmed repeated book references.
October 7, 2026 — Per Dr. Axe's Oct 7 ruling, the pull-quote now calls ghee "one of the richest" dietary sources of butyric acid rather than "the highest," since USDA lists butter at the same 3.23 grams per 100 grams; the quote's source line now names the episode directly.
October 6, 2026 (second update) — Following Dr. Axe's direction of Oct 6, 2026, replaced the pull-quote with his own wording ("Ghee is one of the richest dietary sources of butyric acid available today, which may support gut health and immunity") and rewrote his other quoted lines as complete sentences: the olive oil advice, the once-a-month line and the full Biblio Diet sentence on ghee. Replaced the two-column ghee-vs.-butter table with a four-fat comparison of ghee, butter, coconut oil and beef tallow (calories, saturated fat, butyric acid and vitamin A per tablespoon from USDA FoodData Central; lactose and milk protein; smoke point; best uses; and Dr. Axe's take on each), with a short paragraph after it on coconut oil, tallow and olive oil as the everyday fat. Added two FAQ answers (ghee vs. coconut oil; ghee vs. beef tallow) to both FAQ copies, restated Dr. Axe's ranking as "number four on my list of the top 10 cooking fats," and updated the read time to 24 minutes. Two references added (35, 36). Noted in the vitamin K2 FAQ that USDA hasn't yet published a K2 figure for ghee itself, added a line to the bloodwork module on what the markers can't show, tightened the olive-oil trial bullet, and added a skin FAQ ("Is ghee good for your skin?") to both FAQ copies, sourced to the 2024 Ayurveda review.
October 5, 2026 — Rebuilt to the current DrAxe.com standard. Added the Dr. Axe Score (6.4) with its math, a USDA nutrition table for one tablespoon (recalculated at USDA's 12.8-gram tablespoon), Dr. Axe's ranking of ghee among cooking fats, the human studies of ghee itself (four controlled trials, a 6-week study and two population surveys), a lab measurement of ghee's lactose, the vitamin K2 and butyric acid research, a chart of butyric acid across cooking fats, the Ayurvedic history and golden milk, a ghee-vs.-butter table and one safety section with fatty-liver, milk-allergy and blood-thinner guidance. Set the smoke point to about 485°F, the figure Dr. Axe gives on his show, and replaced "free of lactose and casein" with the measured trace of lactose and a milk-allergy note. Removed the weight-loss, cancer and blood-pressure claims drawn from conjugated linoleic acid and medium-chain fat studies, the bone-density study of vitamin K1, the unsourced history of butter's first use and the general risks list.
References
- US Department of Agriculture, Agricultural Research Service. Butter oil, anhydrous. FoodData Central, SR Legacy, FDC ID 173412 (NDB 1003). Published April 1, 2019.
- US Food and Drug Administration. Daily Value on the Nutrition and Supplement Facts Labels.
- Portnoi PA, MacDonald A. The lactose and galactose content of milk fats and suitability for galactosaemia. Mol Genet Metab Rep. 2015;5:42-43. doi:10.1016/j.ymgmr.2015.10.001. PMID:28649541
- Shankar SR, Yadav RK, Ray RB, Bijlani RL, Baveja T, Jauhar N, et al. Serum lipid response to introducing ghee as a partial replacement for mustard oil in the diet of healthy young Indians. Indian J Physiol Pharmacol. 2005;49(1):49-56. PMID:15881858
- Kataria D, Singh G. Health benefits of ghee: Review of Ayurveda and modern science perspectives. J Ayurveda Integr Med. 2024;15(1):100819. doi:10.1016/j.jaim.2023.100819. PMID:38181707
- Axe J. Seed Oils: Are They Bad for You? What the Research Really Says. DrAxe.com. September 23, 2026.
- Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ, Brummer RJ. Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther. 2008;27(2):104-19. doi:10.1111/j.1365-2036.2007.03562.x. PMID:17973645
- Axe J. You Were Lied To About Seed Oils! The Truth About Butter, Tallow & Olive Oil. The Dr. Josh Axe Show. June 29, 2026 (ghee at 20:01-21:25, including the 485°F smoke point at 20:07-20:15, golden milk at 20:33-20:52 and the once-a-month line and mashed cauliflower at 21:00-21:19; the healthiest oils at 29:02-29:36).
- US Department of Agriculture, Agricultural Research Service. Butter, without salt. FoodData Central, SR Legacy, FDC ID 173430 (NDB 1145). Published April 1, 2019.
- Kumbhare S, Prasad W, Khamrui K, Wani AD, Sahu J. Recent innovations in functionality and shelf life enhancement of ghee, clarified butter fat. J Food Sci Technol. 2023;60(1):11-23. doi:10.1007/s13197-021-05335-7. PMID:36618046
- Kataria D, Singh G. Effect of processing methods on fatty acid composition and flavour profile of clarified butter (ghee) obtained from Deoni and Holstein Friesian cow breeds. Food Chem X. 2025;27:102489. doi:10.1016/j.fochx.2025.102489. PMID:40463655
- Axe J, Rubin J. The Biblio Diet. Hachette Book Group; 2025 (fats chapter, the ghee entry beginning "Ghee, a member of the butter family"). ISBN 9781546008439.
- Ahmadi E, Abdollahzad H, Pasdar Y, Rezaeian S, Moludi J, Nachvak SM, et al. Relationship Between the Consumption of Milk-Based Oils Including Butter and Kermanshah Ghee with Metabolic Syndrome: Ravansar Non-Communicable Disease Cohort Study. Diabetes Metab Syndr Obes. 2020;13:1519-1530. doi:10.2147/DMSO.S247412. PMID:32440181
- Yokogawa T, Yamazaki C, Hara M, Sakashita Y, Tanikawa T, Suzuki R, et al. Effect of Maillard reaction on the quality of clarified butter, ghee. J Nat Med. 2023;77(1):230-237. doi:10.1007/s11418-022-01661-y. PMID:36324007
- Månsson HL. Fatty acids in bovine milk fat. Food Nutr Res. 2008;52. doi:10.3402/fnr.v52i0.1821. PMID:19109654
- US Department of Agriculture, Agricultural Research Service. Oil, coconut. FoodData Central, SR Legacy, FDC ID 171412 (NDB 4047). Published April 1, 2019.
- US Department of Agriculture, Agricultural Research Service. Fat, beef tallow. FoodData Central, SR Legacy, FDC ID 171400 (NDB 4001). Published April 1, 2019.
- US Department of Agriculture, Agricultural Research Service. Oil, olive, salad or cooking. FoodData Central, SR Legacy, FDC ID 171413 (NDB 4053). Published April 1, 2019.
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- Mohammadi Hosseinabadi S, Nasrollahzadeh J. Effects of diets rich in ghee or olive oil on cardiometabolic risk factors in healthy adults: a two-period, crossover, randomised trial. Br J Nutr. 2022;128(9):1720-1729. doi:10.1017/S0007114521004645. PMID:34794522
- Shankar SR, Bijlani RL, Baveja T, Jauhar N, Vashisht S, Mahapatra SC, et al. Effect of partial replacement of visible fat by ghee (clarified butter) on serum lipid profile. Indian J Physiol Pharmacol. 2002;46(3):355-60. PMID:12613401
- Maleki Sedgi F, Mohammad Hosseiniazar M, Alizadeh M. The effects of replacing ghee with rapeseed oil on liver steatosis and enzymes, lipid profile, insulin resistance and anthropometric measurements in patients with non-alcoholic fatty liver disease: a randomised controlled clinical trial. Br J Nutr. 2024;131(12):1985-1996. doi:10.1017/S0007114524000564. PMID:38501177
- Munisekhar K, Singh M SB, Rao PS, Sitaram B, Sharvani N, Kiranmayi VS, et al. Lipid profile in healthy human volunteers before and after consuming ghee. Bioinformation. 2022;18(9):742-747. doi:10.6026/97320630018742. PMID:37426499
- Gupta R, Prakash H. Association of dietary ghee intake with coronary heart disease and risk factor prevalence in rural males. J Indian Med Assoc. 1997;95(3):67-9, 83. PMID:9212571
- Schurgers LJ, Vermeer C. Determination of phylloquinone and menaquinones in food. Effect of food matrix on circulating vitamin K concentrations. Haemostasis. 2000;30(6):298-307. doi:10.1159/000054147. PMID:11356998
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- Fu X, Harshman SG, Shen X, Haytowitz DB, Karl JP, Wolfe BE, et al. Multiple Vitamin K Forms Exist in Dairy Foods. Curr Dev Nutr. 2017;1(6):e000638. doi:10.3945/cdn.117.000638. PMID:29955705
- Axe J. The Truth About LDL & Heart Disease. The Dr. Josh Axe Show. February 23, 2026 (animal fats and olive oil at 22:02-22:47).
- Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS. Reduction in saturated fat intake for cardiovascular disease. Cochrane Database Syst Rev. 2020;8(8):CD011737. doi:10.1002/14651858.CD011737.pub3. PMID:32827219
- Sharma H, Zhang X, Dwivedi C. The effect of ghee (clarified butter) on serum lipid levels and microsomal lipid peroxidation. Ayu. 2010;31(2):134-40. doi:10.4103/0974-8520.72361. PMID:22131700
- Alothman M, Hogan SA, Hennessy D, Dillon P, Kilcawley KN, O'Donovan M, et al. The "Grass-Fed" Milk Story: Understanding the Impact of Pasture Feeding on the Composition and Quality of Bovine Milk. Foods. 2019;8(8):350. doi:10.3390/foods8080350. PMID:31426489
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