
Leaky gut syndrome is a rapidly growing condition that millions of people are struggling with and don’t even know it. From the sound of it, you might think leaky gut syndrome only affects the digestive system, but in reality it can lead to many other health conditions.
According to research, the cause of your food allergies, low energy, joint pain, thyroid disease, autoimmune conditions and slow metabolism could be leaky gut symptoms progression.
In this article, I will outline specifically how you can heal leaky gut syndrome and break through the health problems you’ve been struggling with.
What Is Leaky Gut Syndrome?
Think of the lining of your digestive tract like a net with extremely small holes in it that only allow specific substances to pass through. Your gut lining works as a barrier keeping out bigger particles that can damage your system.

When someone has leaky gut (often referred to as increased intestinal permeability), the “net” in your digestive tract gets damaged, which causes even bigger holes to develop in your net, so things that normally can’t pass through, are now be able to.
Some of the things that can now pass through include proteins like gluten, bad bacteria and undigested foods particles. Toxic waste can also leak from the inside of your intestinal wall into your bloodstream causing an immune reaction.
Leaky Gut Symptoms and Progression
This leads to inflammation throughout your system and can cause symptoms, such as:
- Bloating
- Food sensitivities
- Thyroid conditions
- Fatigue
- Joint pain
- Headaches
- Skin issues like rosacea and acne
- Digestive problems
- Weight gain
- Syndrome X

One of the biggest warning signs that you may have leaky gut — I recommend that you take a leaky gut test — can be that you’re experiencing multiple food sensitivities. Partially digested protein and fat can seep through your intestinal lining, making their way into your bloodstream and causing an allergic response.
This allergic response doesn’t mean you’ll break out in a rash all over your body, but it can lead to one of the symptoms I’ve mentioned above. If left un-repaired, it can lead to more severe health issues like inflammatory bowel disease, IBS, arthritis, eczema, psoriasis, depression, anxiety, migraine headaches, muscle pain and chronic fatigue.
According to the Journal of Diabetes, there is a strong body of evidence pointing to leaky gut syndrome as a major cause of autoimmune diseases, including Type 1 Diabetes.
Another problem with leaky gut is that it can cause malabsorption of vital minerals and nutrients including zinc, iron and vitamin B12.
What Causes Leaky Gut?
There are four main causes of leaky gut which include:
- Poor diet
- Chronic stress
- Toxin overload
- Bacterial imbalance
The most common components of food that can damage your intestinal lining are the proteins found in un-sprouted grains, sugar, GMO’s and conventional dairy.The problem with un-sprouted grains is that they contain large amounts of antinutrients or nutrient blockers called phytates and lectins. Lectins are sugar-binding proteins that act as a natural defense system for plants that protect them from outside invaders like mold and parasites.
This is good news for plants but bad news for your body. Your digestive lining is covered with sugar-containing cells that help break down your food. Lectins gravitate toward this area and when they attach to your digestive lining, it damages your gut and causes inflammation.

Lectins and Foods that Cause Leaky Gut
Lectins are found in many foods, not just grains, and consumed in smaller amounts, your body will do just fine with them. But foods that have large amounts of lectins are more problematic. Some of the lectins and foods that cause leaky gut include wheat, rice, spelt and soy.
Sprouting and fermenting grains reduces phytates and lectins, making these foods easier to digest. GMO and hybridized foods tend to be the highest in lectins since they have been modified to fight off bugs. Also, gluten–containing grains will damage your intestinal lining and cause leaky gut syndrome.
So while you are working to heal leaky gut and cure autoimmune disease, stay away from all grains, especially ones that contain gluten like wheat. Once your gut is healthy, you can add back in grains that have been fermented and sprouted to eat occasionally.
Conventional cows milk is another food that can cause leaky gut. The component of dairy that will harm your gut is the protein A1 casein. Also, the pasteurization process will destroy vital enzymes, making sugars like lactose very difficult to digest. For this reason, I only recommend buying dairy that is raw and from A2 cows, goats, sheep, or buffalo.
Sugar is another substance that will wreak havoc on your digestive system. Sugar will feed the growth of yeast, candida and bad bacteria, which will further damage your gut. Bad bacteria actually creates toxins called exotoxins that damage healthy cells and can eat a hole into your intestinal wall.
Other Factors that Cause Leaky Gut
Chronic stress: It weakens your immune system over time, which cripples your ability to fight off foreign invaders like bad bacteria and viruses, leading to inflammation and leaky gut. To reduce stress, I recommend getting more sleep, schedule fun into your week, rest one day a week, meditate on scripture, and hang out with positive, uplifting people.
Toxins: We come into contact with over 80,000 chemicals and toxins every single year, but the worst offenders for causing leaky gut include antibiotics , pesticides, tap water, aspirin and NSAIDS. I recommend buying a high-quality water filter to eliminate chlorine and fluoride and look to natural plant-based herbs to reduce inflammation in your body.
Dysbiosis: Finally, one of the leading causes of leaky gut is a condition called dysbiosis, which means an imbalance between beneficial and harmful species of bacteria in your gut. For many, this imbalance can begin at birth because of a C-section or because the mother didn’t have a healthy gut herself. The overuse of prescription antibiotic drugs, tap water with chlorine and fluoride, and the lack of probiotic-rich foods contribute to this imbalance of good and bad bacteria.
Leaky Gut and the Brain

Another topic I want to quickly discuss is how leaky gut can affect the brain. If you’ve ever seen a child with autism experience a mood swing, this can be caused by intestinal permeability. Gluten-free and casein-free diets have proven effective for many children with autism because these proteins can leak through the gut and then recirculate and act on the brain similarly to an opioid drug.
This is also why leaky gut syndrome has been linked to other psychological disorders such as anxiety, depression and bipolar disorder. So, in many cases, if you can heal the gut, you can heal the brain.
The 4-Step Plan to Heal Leaky Gut
The good news is there’s a solution to successfully healing leaky gut. There is a four-step process that includes:
REMOVE foods and factors that damage the gut
REPLACE with healing foods
REPAIR with specific supplements
REBALANCE with probiotics
Here’s the protocol I have used with my patients over the years that has helped them see incredible results.
Remember, the top foods to remove that cause leaky gut are sugar, grains, conventional meat, conventional dairy and GMO foods. The top toxic exposures to eliminate are tap water, pesticides, NSAIDS and antibiotics — but remember to always consult with your physician if he or she has prescribed these for you.
The Leaky Gut Diet and 5 Healing Foods
If you suffer from leaky gut syndrome, you’re overdue to consider adopting a leaky gut diet. Here are the five foods and supplements to heal your leaky gut.
#1 Bone Broth – broth contains collagen and the amino acids proline and glycine that can help heal your damaged cell walls. I’ve had many of my patients do a bone broth fast for three days to help heal leaky gut and cure autoimmune disease.
#2 Raw Cultured Dairy – contains both probiotics and SCFA’s that can help heal the gut. Pastured kefir, yogurt, amasai, butter and raw cheese are some of the best.
#3 Fermented Vegetables – contain organic acids that balance intestinal pH and probiotics to support the gut. Sauerkraut, kimchi and kvass are excellent sources.
#4 Coconut Products – all coconut products are especially good for your gut. The MCFA’s in coconut are easier to digest than other fats so they work well for leaky gut. Also, coconut kefir contains probiotics that support your digestive system.
#5 Sprouted Seeds – chia seeds, flaxseeds and hemp seeds that have been sprouted are great sources of fiber that can help support the growth of beneficial bacteria. But if you have severe leaky gut, you may need to start out getting your fiber from steamed vegetables and fruit.
Also, consuming foods that have omega-3 fats are beneficial — anti-inflammatory foods like grass-fed beef, lamb and wild-caught fish like salmon.
Top 5 Supplements for Healing Leaky Gut
There are many supplements that support your digestive health, but I believe the most beneficial leaky gut supplements are l-glutamine, probiotics, digestive enzymes, aloe vera juice, quercetin, NAG and licorice root.
#1 Probiotics are the most important supplement to take because it helps replenish good bacteria and crowds out bad bacteria. I recommend getting probiotics in both food and supplement form. I see people all the time only follow part of the protocol in healing their leaky gut syndrome by removing the damaging irritants. But the part they often leave out is re-inoculating their gut with beneficial bacteria that will keep bad bacteria at bay.
So load up on BOTH probiotic-rich foods and take AT LEAST 50 billion units of probiotics daily from a high-quality brand.
#2 Digestive enzymes (one or two capsules at the beginning of each meal) ensure that foods are fully digested, decreasing the chance that partially digested foods particles and proteins are damaging your gut wall.
#3 L-Glutamine is critical for any program designed to heal leaky gut. Glutamine powder is an essential amino acid supplement that is anti-inflammatory and necessary for the growth and repair of your intestinal lining. L-glutamine benefits include acting as a protector: coating your cell walls and acting as a repellent to irritants. Take 2–5 grams twice daily.
#4 Licorice Root (DGL) is an adaptogenic herb that helps balance cortisol levels and improves acid production in the stomach. DGL supports the body’s natural processes for maintaining the mucosal lining of the stomach and duodenum. This herb is especially beneficial if someone’s leaky gut is being caused by emotional stress. Take 500 milligrams twice daily.
#5 Quercetin has also been shown to improve gut barrier function by sealing the gut because it supports creation of tight junction proteins. It also stabilizes mast cells and reduces the release of histamine, which is common in food intolerance. New studies have also shown its effectiveness in healing ulcerative colitis. Take 500 milligrams three times daily with meals.
If you can follow the above protocol, you are well on your way to successfully treating your gut for good.
Read Next: 7 Signs and Symptoms You Have Leaky Gut
References:
Kiefer D, Ali-Akbarian L (2004). “A brief evidence-based review of two gastrointestinal illnesses: irritable bowel and leaky gut syndromes”. Alternative Therapy Health Medicine 10 (3): 22–30.
Pike, M. G.; Heddle, R. J.; Boulton, P.; Turner, M. W.; Atherton, D. J. (1986). “Increased Intestinal Permeability in Atopic Eczema”. Journal of Investigative Dermatology 86 (2): 101–104.
Humbert, P.; Bidet, A.; Treffel, P.; Drobacheff, C.; Agache, P. (1991). “Intestinal permeability in patients with psoriasis”. Journal of dermatological science 2 (4): 324–326.
Vaarala O, Atkinson MA, Neu J (2008) ‘The “Perfect Storm” for Type 1 Diabetes The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity’, Diabetes Journal, (57)10(2555-2562).
Z Liu, N Li, J Neu (2005) ‘Tight junctions, leaky intestines, and pediatric diseases’, Acta Paediatrica , 94(4), pp. 386-393.
Maes M, Leunis JC (2008) ‘Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria’, Journal of Neuro Endocrinology, 29(6), pp. 902-10.
Visser, J (2010) Tight Junctions, Intestinal Permiability and Autoimmunity Celiac Disease and Type 1 Diabetes Paradigms. PubMed.














I was having serious issues with acid reflux and leaky gut. I have changed my diet to a lot of the above suggestions. I also added a teaspoon of organic apple cider vinegar with lemon in 6 oz. of water to my morning regiment, I also heat up and drink organic cold brew coffee since it has less acidic effects with a teaspoon of coconut oil instead of half and half, which makes it taste different but I don’t miss the milk at all. When I first started this new way of being healthy, I drank the solution 30 minutes before every meal until I felt better, now I only have to drink it in the morning. I feel so much better. My bowls weren’t working right and I seriously thought I was having a heart attack. I no longer feel sluggish or fatigued. Thanks for all your information Dr. Axe. I share your knowledge and how to hook up your sites with my friends often. Thanks Sheila
I HAVE PRICKLY HEAT ,LOOK LIKE ARTICARIA ,DOES THAT CAUSES FROM LEAKY GUT I WANT TO KNOW
It’s possible
I would like to follow your protocol for healing Leaky Gut. I have a question though about the bone broth-How to you make it? Do you have a preferred way of making it, and if so, can you please share?
Check this out: https://draxe.com/recipe/chicken-bone-broth-2/
This is a question and do you send the reply to me personally I hope so
What is spouted flax seed meal it is in your smoothie
i have started l glutamine for about a week already , it works good and may i ask you how long should i be taking this? Tnx and God bless
It’s up to you. I take it every day to proactively support gut health!
Dear Dr.Axe: Confessions of a sugar addict! I have been suffering with abdominal cramping and GERD for about 8 years. I had my gallbladder out in 2009 and in 2010 made a trip to the ER with a LES spasm that I thought was a heart attack. The upper GI scope showed my stomach to be ulcerated and I was prescribed NEXIUM. Symptoms were improved for about a year and then they gradually returned. I went on a paleo diet, which included cutting out all sugar and carbs. I noticed that my symptoms went away so I stopped taking the NEXIUM. Long story short, I gradually fell off the diet and then started having migraine headaches. I’ve gained an enormous amount of weight for my frame and now have noticed swelling in my hands, knees and feet. I am an active person and at 48 years old I’m beginning to feel as if I’ve aged to 60. Actually I know people in their 60’s that are healthier than I am. Where should I start? It seems like the cravings for sugars and carbs are impossible to curb. I want my health back! Thanks!
Check this out: https://draxe.com/leaky-gut-diet-treatment/
Hi doc. Axe, for more than 3 years now, I have been having severe stomach pain,severe anxiety,depression,low energy, I have gone to the hospital without any solution. The anxiety and depression is getting worse day by day, I get shaky most of the time, I think I have leaky gut, I am not adding weight even after consuming a lot of food, I am thin, please help me
Check these out:
https://draxe.com/natural-remedies-depression/
https://draxe.com/natural-remedies-anxiety/
https://draxe.com/3-steps-to-heal-adrenal-fatigue/
I have been under the impression that eggs aren’t good for leaky gut, is that true? I find a lot of recipes call for eggs and I’ve been subbing with flaxseed and water but they don’t always turn out and looking for something more filling and more calories. When I first started this plan I felt stomach pains and odd bowel movements which is new but it stopped for the past 5 months so figure I was getting use to all the fiber, but cramps are back again as of last week and I’m curious if Almonds and the seeds listed would cause that? I have chia and hemp and almonds/almond butter and a lot of coconut as a big stable of my diet but I’m wondering if thats come back to hurt me, i’ve never had food intolerances or IBS in my life so its concerning to have it now. I have only gone to this diet to benefit my skin condition (Vitiligo). Just odd that the pains we’re gone but back again, any insight would be appreciated.
Some people tolerate them while others do not. They are more likely to cause issues in people than other foods but again, everyone is different!
It is possible that almonds and a diet high in nuts and seeds could cause stomach cramping. They should be consumed in small amounts. I would focus on eating to promote gut health for awhile and see how your body does. Check this out:
https://draxe.com/leaky-gut-diet-treatment/
Dr Axe,
I have leaky gut and had ALCAT test done. Even when I remove those foods, I still get histamine reactions…severe palpitations with every meal. I have had to stop my homemade kefir and fermented veggies and homemade broth due to the histamines. Even L-glutamine reacts. I don’t know what to do next. I don’t have any knowledgeable doctors in my area. HELP please
I would do FODMAPs for 2 weeks and then immediately start the GAPS diet but still eliminate high histamine foods
I have a number of symptoms and after reading several of your articles on different aliments there are several things I suffer from – leaky gut (IBS), adrenal fatigue, chronic fatigue, weight gain and hormonal imbalances. Which diet plan could address all of these issues? Thanks! Love your articles!!!
I would focus on healing your gut as many issues can stem from that