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The Dr. Josh Axe Show

The Gut Damage Cascade

Transcript

Josh

Low fiber intake, taking drugs and medications like antibiotics, and chronic stress. Those three things are the single biggest things destroying your gut microbiome: low fiber and low nutrient intake, antibiotics, chronic stress, and I would also throw as a fourth one in there, overconsumption of sugar. With that, you have loss of microbial diversity. Well, when you have less microbial diversity, now your gut produces less short chain fatty acids like butyrate. Now your gut barrier weakens, causing leaky gut. Leaky gut then allows endotoxins and undigested food particles and toxins into your bloodstream. That creates chronic low-grade inflammation. That inflammation that happens over and over and over again leads to increased insulin, obesity, depression, irritable bowel disease, and over time, autoimmune disease. This is the exact cascade that happens in almost every person with autoimmune disease, IBD, depression, and obesity.

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