Herbs & Spices · Immune herbs
Echinacea: Benefits, Uses, Tea and Dosage for Colds and Flu
What echinacea does for colds and flu, how it works in your body, which species and part to use, how much to take and when, how to make echinacea tea, and who should skip it.

Why this score?
Weighting: Evidence 30% · Traditional Medicine 25% · Clinical Effectiveness 25% · Safety 20% (6.6×0.30 + 8.6×0.25 + 7.4×0.25 + 8.0×0.20 = 1.98 + 2.15 + 1.85 + 1.60 = 7.58, shown as 7.6). Interactions are rated separately and don't change the score. How we score
Interaction check: Moderate. Echinacea may work against medicines that suppress the immune system, and it can change how fast some medicines are cleared. Interactions are rated separately and don't change the score.
Immune-suppressing medicines, such as tacrolimus after a transplant: echinacea stimulates immunity and may work against these drugs, so ask the doctor managing your treatment before you take it.2
Medicines cleared by the liver enzyme CYP3A, such as midazolam: echinacea root changed how fast midazolam was cleared in one of two small studies, so ask your pharmacist whether your medicine is one of them.3637
On this page

Is echinacea one of your top 5?
What's your biggest goal right now?
Echinacea is the purple coneflower of the North American prairie, and it helps your immune system answer a cold or flu faster, above all when you start it at the very first sign. In a placebo-controlled trial of 755 adults, four winter months of echinacea meant about 21% fewer days with a cold.1 In Western herbal tradition it's a cooling herb for the lungs, best for hot, early infections.2
- What it does: fewer colds, fewer repeat respiratory infections, and in a trial of 473 people with flu, an echinacea hot drink made with elderberry did as well as the antiviral drug oseltamivir34
- How much: 300 to 600 mg of extract two to three times a day, or 2.5 mL of tincture three times a day, while you're sick52
- How to use it: start on the first day of a scratchy throat or sniffles, and keep going through the days you're sick2
- As a tea: 1 to 2 teaspoons of the dried herb steeped for 10 minutes, 2 to 3 cups a day2
Echinacea is the purple coneflower, a North American prairie herb whose flowers, leaves and roots are taken as a tea, tincture or extract to help your body fight off colds and flu. I use it at the first sign of illness rather than long-term, at 300 to 600 mg of extract two to three times a day while you're sick, because it activates the innate immune cells that make up your first line of defense.52
A scratchy throat or a tickle in your nose is the first sign that a virus has landed on the lining of your airways, and how fast your immune system answers over the next few days goes a long way toward deciding how hard that cold hits you. That's why echinacea works best taken at the very first sign.2 Getting to the root cause of a rough cold season means working on both halves: fighting a cold fast the moment it starts, and building your defenses before the season with good sleep, time outdoors, vitamin D and zinc.6 For longer-term immune strengthening, my top two herbs are astragalus and reishi.6
Native American healers used the purple coneflower for infections, wounds and snakebite long before it reached Europe, and today it's one of the best-selling immune herbs on earth.2 Researchers have now tested echinacea in dozens of placebo-controlled trials,78 and its strongest results match how those healers used it, against infection: fewer colds and fewer repeat respiratory infections.13
Echinacea has been shown to be good for sore throats. That's one I recommend.Dr. Josh Axe, DC, DNM, CNSFrom How to Prevent & Heal Cold & Flu Naturally (Foods, Supplements, & Herbs for Rapid Recovery), The Dr. Josh Axe Show (2024)
Get the free Top 50 Healing Herbs & Essential Oils guide
Echinacea has its own entry in my free field guide, and echinacea tincture is one of the five remedies in its cold and flu kit. Inside you'll find:
- 30 healing herbs and 20 essential oils, with the five best uses of each, ranked by the research
- How to take each one, how it works in your body, its traditional energetics and when to be careful
- The natural medicine cabinet to keep at home, cold and flu kit included
Free with your Dr. Axe account (email or Google). You'll also get the protocol's short email series and the Dr. Axe newsletter; unsubscribe anytime.
Open the free guide →Did you know?
Each medicinal species has its own common name: Echinacea purpurea is the purple coneflower, E. angustifolia the narrow-leaved coneflower and E. pallida the pale purple coneflower.910
In a 2009 lab study, a standardized echinacea extract inactivated bird flu and swine flu viruses in cell culture, at concentrations from the recommended oral dose down to far lower ones.11
European regulators recognize medicines made from purple coneflower herb for the common cold in adults and teens over 12.12
What is echinacea?
Echinacea is a group of North American coneflowers in the daisy family, and three species are used as medicine: Echinacea purpurea, E. angustifolia and E. pallida.9 The flowering tops, leaves and roots are made into teas, tinctures, capsules and throat sprays, and E. purpurea is the species in many cold and flu products and in the prevention and flu trials on this page.914
The coneflowers grow wild on the prairies of North America, with purple petals around a raised, spiny center.13 Each species and each part of the plant carries its own mix of active compounds, including alkylamides, caffeic acid derivatives such as cichoric acid and echinacoside, and polysaccharides, and no single compound explains what echinacea does, which is why the whole plant part matters more than any one marker.910
A short history of echinacea
Native American tribes used echinacea for mouth sores, colds and snakebite, and prairie peoples reached for its roots for painful conditions of all kinds.1413 Like turmeric in the healing traditions of Southeast Asia, it's one of the time-tested remedies that cultures around the world have relied on for vitality, immunity and balance.5
The prairie where it grows is a living picture of Psalm 104:14: "He causeth the grass to grow for the cattle, and herb for the service of man: that he may bring forth food out of the earth."
What is echinacea good for?
Echinacea is good for colds and flu: in placebo-controlled trials it meant fewer colds over a winter and fewer repeat respiratory infections, and an echinacea hot drink with elderberry did as well as the antiviral drug oseltamivir for the flu.134 A sore throat or stuffy nose means your immune system is already fighting a virus at your front line, and echinacea backs up that first response.2
| Use | Evidence | Product studied | What the research shows |
|---|---|---|---|
Fewer colds | Good | Echinacea extracts, mostly E. purpurea | About 21% fewer days with a cold over four winter months in 755 adults1 |
Fewer repeat infections | Good | Standardized E. purpurea extracts | About 35% lower risk across 6 placebo-controlled trials of 2,458 people3 |
Shorter colds | Mixed | Extracts and teas started at the first symptoms | About 1.4 days shorter across 7 studies in a 2007 meta-analysis15 |
Flu | Moderate | Hot drink of E. purpurea with elderberry juice | Did as well as oseltamivir in 473 people with early flu4 |
Sore throat | Emerging | Echinacea and sage throat spray | Did as well as a medicated throat spray in 154 people16 |
Calmer mood | Emerging | Low-dose E. angustifolia root extract | Less anxiety in one placebo-controlled trial and better mood in another1718 |
Skin | Emerging | E. purpurea creams and gels | Better hydration and fewer fine lines in 10 volunteers; calmer eczema with an alkylamide cream1920 |
Pain and inflammation | Traditional | Echinacea roots | A traditional prairie remedy for painful conditions; eased inflammatory pain in mice13 |
What does echinacea do for the body?
Echinacea works in your body by waking up your immune system's first responders and keeping their response in balance. It activates macrophages and natural killer cells, calms excess inflammation through the CB2 receptor on immune cells, and in lab studies it deactivates viruses wrapped in a fatty coat, such as flu viruses.22111
Think of the lining of your nose and throat as a guard post. The macrophages and natural killer cells stationed there are the guards who meet a virus first, and echinacea helps rouse them while keeping them from overreacting, so they do their job without flooding your airways with inflammation.2 In mice, daily echinacea in the diet raised the number of natural killer cells,22 and the steps below show how its compounds reach and tune your immune cells.
In 11 healthy adults, the alkylamides from an echinacea root extract reached their peak in the blood about 30 minutes after a single dose.23
In lab studies, those alkylamides bound the CB2 receptor of your endocannabinoid system more strongly than the body's own endocannabinoids, and they tuned the inflammatory messenger TNF-alpha in human immune cells.2124
In human airway cells infected with a cold virus, echinacea extract blocked the alarm signals IL-6 and IL-8, whether it was added before or after the infection.25
In flu-infected airway cells, it turned down the surface receptors bacteria use to latch on, the setup for a secondary infection.26
Those alarm signals are cytokines, the messengers that bring on the aches, swelling and congestion of a cold, and in lab studies echinacea helps keep them in proportion while your defenses work on the virus.25 All of this happens at your front line in the first hours of an infection, so echinacea works best when it's on board from the very first sign.2
Echinacea in traditional herbal medicine
I treat echinacea the way Native American and Western herbal tradition does: as a cooling herb with a pungent, bitter taste that goes to the lungs. It's best for hot, early infections: a sore throat, swollen glands, a fever, and the tingle on your tongue that tells you a cold is coming.2
That makes echinacea one of the cooling foods and herbs, the ones the tradition matches to a cold that comes on hot and fast.2
Echinacea benefits
Echinacea's best-studied benefits all involve your airways: fewer colds, fewer repeat infections, shorter colds when you start early, flu recovery on par with an antiviral drug when it's paired with elderberry, and a calmer sore throat. Its research on mood, skin and pain is younger and encouraging.
Fewer colds through the season
Good evidenceHuman studyPlacebo-controlled trial of 755 adults over 4 winter months; 2007 meta-analysis of 14 studies; 2014 Cochrane review of 24 trials; 2019 meta-analysis of placebo-controlled trialsTaken through cold season, echinacea helps you catch fewer colds, and the colds you do catch take up fewer days. At Cardiff University's Common Cold Centre, 755 healthy adults took an alcohol extract of fresh E. purpurea or a matching placebo for four winter months: 2,400 mg of extract a day, raised to 4,000 mg whenever they felt a cold coming on, and neither the people nor the researchers knew who got what. The echinacea group had 149 colds against 188 on placebo, and 672 days with a cold against 850, about 21% fewer, a drop in cold days too large to put down to chance. Like several trials on this page, it had authors from the product's maker.1
The pooled studies point the same way. A 2007 meta-analysis of 14 studies found 58% lower odds of catching a cold in the 9 studies that counted new colds, from a mix of products that included some combinations,15 and a 2019 meta-analysis of placebo-controlled trials found a 22% lower risk.27 The 2014 Cochrane review of 24 trials and 4,631 people kept to single-herb products, and when its prevention trials were pooled, they pointed to a 10% to 20% lower risk of a cold.7
Study takeaway: about 21% fewer days with a cold over four winter months.
Four winter months of echinacea: about 21% fewer days with a cold
Fewer repeat infections and complications
Good evidenceHuman study2015 meta-analysis of 6 placebo-controlled trials · 2,458 people; 2024 meta-analysis of 30 trials · 5,652 people; blinded trial of children 4 to 12 against vitamin CIf you catch one cold after another, echinacea helps break the cycle, and it lowers the odds that a cold turns into something more, such as an ear infection or pneumonia. A 2015 meta-analysis of 6 placebo-controlled trials with 2,458 people found about a 35% lower risk of repeat respiratory infections on echinacea, and in the 3 studies of people who were more prone to infections, through stress or weaker immunity, the risk was cut in half. Complications such as pneumonia, ear infections and tonsillitis were about half as common as well.3
In the Cardiff trial, people on echinacea had 65 repeat colds against 100 on placebo,1 and a 2024 meta-analysis of 30 trials with 5,652 people found about 70% fewer days on antibiotics, with alcohol extracts of fresh E. purpurea showing the largest drop.28
Children showed the same pattern. In a randomized, controlled trial in Switzerland, 103 children aged 4 to 12 took 400 mg tablets of fresh-plant E. purpurea three times a day and 98 took a small daily dose of vitamin C (50 mg three times a day), for two 2-month stretches. The echinacea group had 429 days with a cold against 602, needed 6 courses of antibiotics against 24, and had 11 complications against 30.29
Study takeaway: 6 courses of antibiotics against 24 for children on echinacea.
Children on echinacea needed 6 courses of antibiotics, against 24
Shorter colds when you start early
Mixed evidenceHuman study2007 meta-analysis of 14 studies; placebo-controlled tea trial of 95 adults; 2010 trial of 719 people; 2014 Cochrane review; induced-cold trial of 437 volunteersStarted at the first sign of a cold, echinacea can help it clear sooner. In the 2007 meta-analysis, the 7 studies that measured cold length found colds 1.4 days shorter on echinacea,15 and in a placebo-controlled trial of 95 adults with early cold or flu symptoms, people who drank an echinacea blend tea improved sooner and were sick for fewer days than those on a placebo tea.30
The trials that tested echinacea once a cold had started don't all agree. In a 2010 trial of 719 people in Wisconsin, echinacea root tablets trended toward a half-day shorter cold, 6.34 days against 6.87 on placebo, a difference too small to be sure of, and the Cochrane review found a clear effect on the length of a cold in 1 of its 7 treatment trials.317 In a trial that exposed 437 volunteers to a cold virus on purpose, E. angustifolia root, rather than the E. purpurea herb used in the prevention trials, made no difference in infection or symptoms.32 Results vary with the product and the timing, so start on the first day and, as the Cardiff volunteers did, take more during the days you feel a cold coming on.1
Flu recovery on par with an antiviral drug
Moderate evidenceHuman studyRandomized trial against oseltamivir · 473 people with flu symptoms for 48 hours or less; blinded trial of children 4 to 12Echinacea helps you get over the flu, and in a head-to-head trial, an echinacea hot drink made with elderberry did as well as the antiviral drug oseltamivir. In the Czech Republic, 473 people ages 12 to 70 with flu symptoms for 48 hours or less took either a hot drink of E. purpurea extract with fresh elderberry juice added, 5 mL stirred into hot water five times a day for 3 days and then three times a day for 7 days, or oseltamivir for 5 days, each group with a dummy version of the other treatment so no one knew which was real.4 Among the 420 who completed it as planned, 90.1% had recovered by day 10, with symptoms gone or mild, against 84.8% on the drug, and the drink caused fewer side effects, especially nausea and vomiting.4
The drug got off to a faster start, with 4.1% recovered by the end of day 1 against 1.5% on the drink, and by day 5 the two were about even, at 50.2% on the drink and 48.8% on the drug. Complications ran 2.46% on the drink and 6.45% on the drug, a gap too small to be statistically certain.4 Since elderberry was in the drink, the result belongs to the pair, and that's how I take them when I feel something coming on.33 In the children's trial, flu was confirmed 3 times in the echinacea group against 20 times in the vitamin C group.29
Study takeaway: 90.1% recovered by day 10 on the echinacea drink, against 84.8% on oseltamivir.
Echinacea-elderberry drink vs. oseltamivir: share recovered
Soothes a sore throat
Emerging evidenceHuman studyRandomized trial against a chlorhexidine and lidocaine throat spray · 154 people 12 and older with an acute sore throatAn echinacea and sage spray calmed a raw throat as well as a standard medicated throat spray. In 11 Swiss general practices, 154 people 12 and older with a sore throat that had started within 3 days used either the echinacea-sage spray or a spray of chlorhexidine and lidocaine, 2 puffs every 2 hours up to 10 times a day for up to 5 days, each with a dummy version of the other. Among the 133 people analyzed per protocol, 63.8% on the echinacea-sage spray had cut their symptoms at least in half by day 3, against 57.8% on the medicated spray, and the time until they were free of symptoms was about the same.16
When you feel a sore throat coming on, I recommend making Manuka honey your only sweetener, taking high doses of propolis three times a day, and adding plenty of echinacea and thyme as an herbal tea.34 Our guide to sore throat remedies covers the rest of that routine, and a warm cup of the echinacea tea below is a soothing place to start.
Calmer mood support
Emerging evidenceHuman studyPlacebo-controlled trials of a low-dose E. angustifolia root extract · adults with high anxiety scores for 7 days; 108 adults with mild to moderate anxiety for 6 weeksA low-dose extract of E. angustifolia root has eased anxiety and lifted mood in placebo-controlled trials. In Hungary, adults with high anxiety scores took 40 mg twice a day for 7 days, and their anxiety scores fell by about 11 points against about 3 on placebo, an improvement that held through 3 weeks off the extract.17 In a 6-week trial of 108 adults with mild to moderate anxiety, 20 or 40 mg twice a day didn't lower anxiety scores more than placebo, but mood and emotional well-being improved more than on placebo.18 These are small, specific doses of a root extract, quite different from a cold-season tincture, and they fit alongside the other natural remedies for anxiety that calm a stressed nervous system.
Skin hydration and calmer skin
Emerging evidenceHuman study10 healthy volunteers for 1 month, no comparison group; randomized trials of an alkylamide cream in eczemaApplied to your skin, echinacea creams and gels have improved hydration and smoothed fine lines, and an echinacea cream calmed eczema. In 10 healthy volunteers aged 25 to 40, an E. purpurea cream and gel used for a month raised skin hydration and reduced wrinkles by 9.47% with the cream and 14.92% with the gel, with no skin irritation, in a study that had no comparison group.19 A cream made with E. purpurea alkylamides calmed inflammation in skin cells, and in randomized trials it lowered eczema scores and raised the skin's protective ceramides by day 15.20 (Our guide to eczema treatment covers the rest of a calm-skin routine.) Native American healers used the plant on wounds as well, so its place on the skin goes back a long way.2
Pain and inflammation support
Traditional useTraditional useTraditional use by prairie peoples; root extracts in cell and mouse studiesPrairie peoples reached for echinacea root for painful conditions, and its root compounds act on the body's own pain-calming system.13 In cell studies, extracts of echinacea roots and their alkylamides acted on cannabinoid receptors, and in mice they reduced inflammatory pain.13
Echinacea root vs. flower: which part to use
Both the root and the flowering herb of echinacea are medicine, and they carry different mixes of compounds: E. purpurea is rich in cichoric acid, the roots of E. angustifolia and E. pallida are rich in echinacoside, and alkylamides matter in E. purpurea and E. angustifolia.9 For colds, choose E. purpurea herb with a little root, the preparation used in the large prevention and flu trials on this page.14
For colds and flu, the preparation to reach for is an alcohol extract of fresh E. purpurea, about 95% herb and 5% root, which is what the Cardiff winter trial and the flu trial both used,14 and in the 2024 meta-analysis, alcohol extracts of fresh E. purpurea showed the largest drop in antibiotic use.28 Echinacea root has its own uses: the alkylamides in the blood-level study came from an E. angustifolia root extract, the mood trials used a low-dose E. angustifolia root extract, and the root is what prairie peoples used for pain.23171813
Labels matter here, because some echinacea products haven't matched their stated species or quality standards when tested.9 Look for the Latin name and the part used, and choose an extract made from fresh E. purpurea herb, with or without some root, when your goal is fewer colds.
How to use echinacea
Use echinacea at the very first sign of a cold or flu, a scratchy throat, a tickle in your nose or a run-down feeling, and keep taking it through the days you're sick, as a tincture, capsules or tea.2 Through cold season, it can also be taken steadily to cut how often you get sick, the way the 4-month winter trial used it.21
If you wake up with a little bit of a sore throat, that's the day to start. Those first 3 days are the most important time to do everything you can, so take your elderberry and echinacea and start drinking ginger and thyme herbal tea.6 When I can tell I'm starting to fight something, I start taking my elderberry, echinacea and vitamin D right away, and the last time I did that, along with a nutrient IV, I hardly had any symptoms at all.33
Elderberry and echinacea both start with an E, and in clinical studies both shorten your overall cold and flu time.6 Echinacea tincture sits in my cold and flu kit next to elderberry syrup, eucalyptus oil for steam, oregano oil capsules and holy basil tea,2 and our guide to natural cold remedies lays out the rest of the plan, from chicken bone broth to rest.
Starting early matters most over the holidays, when houses fill up with family and guests and a cold can travel from one person to the next.
If you feel like a cold or flu is coming on, fight it fast. Do everything you can in the early stages. Or if people in your house are sick, go ahead and start doing those remedies right now.Dr. Josh Axe, DC, DNM, CNSFrom How to Prevent & Heal Cold & Flu Naturally (Foods, Supplements, & Herbs for Rapid Recovery), The Dr. Josh Axe Show (2024)
Markers to check before cold and flu season
Vitamin D and zinc are two foundations of a ready immune system, and a blood test shows where you're starting. Our guide on how to boost your immune system covers the rest.
- Vitamin D (25-hydroxy): The form your body stores and the one a lab measures. The optimal range is 50 to 80 ng/mL.
- Zinc: A serum zinc test is the lab measure for it.
See the cellular bloodwork panel
Have results? Analyze them free →Echinacea dosage and forms
At the first symptoms, take 2.5 mL of echinacea tincture three times a day, 300 to 500 mg in capsules three times a day, or 2 to 3 cups of echinacea tea, and keep going through the days you're sick.2 For an extract, my range is 300 to 600 mg two to three times a day during an acute illness.5
Echinacea tops my list of prescriptions for the common cold, at 5 mL twice a day for 10 days.35 Each form has its own amount:
Tincture or drops: 2.5 mL three times a day at the first symptoms.2 The Cardiff volunteers took 0.9 mL three times a day, raised to five times a day during a cold, with each dose diluted in a little water and held in the mouth for 10 seconds before swallowing.1
Capsules or tablets: 300 to 500 mg three times a day for acute use.2 The children's trial used 400 mg tablets three times a day.29
Tea: 1 to 2 teaspoons of the dried herb steeped for 10 minutes, 2 to 3 cups a day; the recipe is below.2
Hot drink: the flu trial's drink was 5 mL of echinacea syrup with elderberry stirred into hot water, five times a day for 3 days and then three times a day for 7 days.4
Throat spray: in the sore throat trial, 2 puffs every 2 hours, up to 10 times a day for up to 5 days.16
Echinacea works best from the first sign of illness rather than long-term.5 For prevention, it can also be taken daily through cold season rather than all year round, and daily use has been studied for up to 4 months.2
Ask Dr. Axe AI. Answers are grounded in this library, with sources shown.
Echinacea tea benefits and how to make it
Echinacea tea gives you the herb in a simple, traditional form, warm and easy on a sore throat, and the warmth and steam soothe your airways while you sip. In the placebo-controlled trial of 95 adults with early cold or flu symptoms, people drank 5 to 6 cups of an echinacea blend tea on the first day, tapering to 1 cup over 5 days, and they recovered sooner than on a placebo tea; the tea blended echinacea with other herbs, so the result belongs to the blend.30 For everyday sick-day use, 2 to 3 cups a day is the amount I recommend.2
Like other herbal teas, it's easy to make your own from dried echinacea herb or root. Sweeten it with a teaspoon of raw local honey or Manuka honey once it has cooled enough to sip, and add a slice of fresh ginger or a sprig of thyme if you like, since both belong in a sick-day cup anyway.6
Ingredients
- 1 to 2 teaspoons dried echinacea herb or root
- 1 cup just-boiled water
- A slice of fresh ginger or a sprig of fresh thyme (optional)
- A squeeze of lemon (optional)
- 1 teaspoon raw local honey or Manuka honey (optional)
Instructions
- Put the echinacea, and the ginger or thyme if you're using it, in a mug or teapot.
- Pour the just-boiled water over it, cover and steep for 10 minutes.
- Strain into a mug and add the lemon.
- Let it cool until it's comfortable to sip, then stir in the honey.
- Drink 2 to 3 cups a day while you're sick.
Echinacea side effects, allergies and who should skip it
Echinacea is well tolerated. Across 48 trials with 10,115 people, reported side effects and other health problems were slightly less common on echinacea than on the comparison treatments, 22.7% against 24.8%, and serious events were rare in both groups, 0.09% against 0.08% of the events recorded.8 Stomach upset and rash are the most common complaints.14
Allergy to the daisy family. Echinacea belongs to the daisy family, along with ragweed, chrysanthemums and marigolds, and European regulators say it shouldn't be used by anyone allergic to plants in that family.12 Serious reactions are rare, and they cluster in people with other allergies: of 51 reports of reactions in Australia, 26 pointed to a possible allergic reaction, including 4 cases of anaphylaxis, and in 100 people with allergies who had never taken echinacea, 20% tested positive on a skin test.38 If you have a ragweed allergy, react to daisies or have a history of severe allergies or asthma, skip echinacea.
Autoimmune disease. Immune-stimulating supplements, echinacea among them, were followed by autoimmune flares in three documented cases.39 With autoimmune disease, ask your practitioner before you take it, and if you're working to calm an overactive immune system, our guide to leaky gut is a good place to start.
Pregnancy and breastfeeding. In a study of 206 women who took echinacea in pregnancy, 6 babies had major birth defects against 7 among 206 matched women who didn't, and a Norwegian study of 68,522 pregnancies, 363 of them with echinacea, found no rise in birth defects.4041 Echinacea's alkylamides were found in one nursing mother's milk, and there are no safety data in nursing mothers or babies.10 During pregnancy and nursing, avoid most concentrated herbs unless your practitioner approves, and if you do use echinacea, confirm the dose with your OB.2
Children. In a placebo-controlled trial of 407 children aged 2 to 11, a rash appeared in 7.1% of the colds treated with echinacea against 2.7% on placebo.42 For a child, ask your practitioner first and choose an alcohol-free form.
When to stop or get care. Stop at any hives, swelling of your lips or face, or wheezing, and get care right away. A cold that lasts more than 10 days needs a doctor,12 and so does one that comes with trouble breathing or a high fever.
The bottom line
Should you take echinacea?
Yes, if you want a natural way through cold and flu season. Echinacea is the purple coneflower Native American healers relied on for infections and wounds, and in modern trials it meant fewer colds over a winter, fewer repeat respiratory infections and fewer antibiotics, while a hot drink of echinacea with elderberry did as well as an antiviral drug for the flu. It has also eased anxiety in a placebo-controlled trial and improved skin hydration.
Keep a bottle of tincture or capsules at home and start the day a cold begins: 300 to 600 mg of extract two to three times a day, or 2.5 mL of tincture three times a day, through the days you're sick, alongside elderberry, a cup of ginger and thyme tea and plenty of rest. Get your sleep, sunshine and vitamin D in place before the season, and let echinacea do its work at the first sign.
Get the free Top 50 Healing Herbs & Essential Oils guide
My field guide to 30 healing herbs and 20 essential oils: the five best uses of each, ranked by the research, how to take it and when to be careful, plus a cold and flu kit with echinacea tincture and elderberry syrup. Free with your Dr. Axe account (email or Google). You'll also get the protocol's short email series and the Dr. Axe newsletter; unsubscribe anytime.
Open the free guide →Echinacea: frequently asked questions
What is echinacea good for?
Echinacea is good for colds and flu. In a placebo-controlled trial of 755 adults, four winter months on echinacea meant 672 days with a cold against 850, and a 2015 meta-analysis of 6 placebo-controlled trials found about a 35% lower risk of repeat respiratory infections.13 Smaller trials, including a randomized trial of 154 people with sore throats, also point to soothing a sore throat, calming anxiety and improving skin hydration.161719
Does echinacea really work for colds?
Yes, it works best for preventing colds and for cutting them short when you start early. A 2007 meta-analysis of 14 studies found 58% lower odds of catching a cold in its 9 studies that counted new colds, and colds about 1.4 days shorter in its 7 studies of cold length.15 In a placebo-controlled trial of 755 adults, people on echinacea had about 21% fewer days with a cold over four winter months.1 For the best chance of a shorter cold, start it at the first sign.
Does echinacea help with the flu?
Yes. In a randomized trial of 473 people with flu symptoms for 48 hours or less, a hot drink of echinacea with elderberry juice did as well as the antiviral drug oseltamivir: among the 420 who completed it as planned, 90.1% had recovered by day 10, against 84.8% on the drug, with fewer side effects.4 Start it within the first day or two of symptoms.
How much echinacea should I take a day?
Can you take echinacea every day?
I use echinacea at the first sign of illness rather than long-term, though through cold season it can also be taken daily.52 Daily use has been studied for up to 4 months, including a placebo-controlled trial of 755 adults over a winter, so take it through the season or on sick days rather than all year round.1
Can you take echinacea and elderberry together?
What are the benefits of echinacea tea?
Echinacea tea is a soothing drink for a sore throat. In a placebo-controlled trial of 95 adults with early cold or flu symptoms, an echinacea blend tea, 5 to 6 cups on the first day tapering to 1 over 5 days, brought faster recovery than a placebo tea.30 Steep 1 to 2 teaspoons for 10 minutes and drink 2 to 3 cups a day while you're sick.2
Is echinacea good for men?
Is echinacea safe for kids?
In children's trials, echinacea was well tolerated overall, and the results on benefit were mixed. In a randomized trial of children aged 4 to 12, 103 on echinacea tablets and 98 on vitamin C, the echinacea group needed 6 courses of antibiotics against 24; in a placebo-controlled trial of 407 children aged 2 to 11, echinacea didn't shorten colds, side effects overall were no more common, though a rash appeared in 7.1% of treated colds against 2.7% on placebo.2942 Choose an alcohol-free form, and the safety section covers the rest.
What are the side effects of echinacea?
Echinacea's side effects are usually mild and slightly less common than on the comparison treatments: across 48 trials with 10,115 people, 22.7% reported side effects or other health problems on echinacea against 24.8% on the comparison.8 Stomach upset and rash are the most common, and the rare serious reactions are allergic, mostly in people allergic to ragweed, daisies or other plants in the same family.1438
Is echinacea safe during pregnancy?
Its safety in pregnancy isn't established, though two studies found no rise in birth defects, one of 206 women who took echinacea and one of 68,522 pregnancies that included 363 with echinacea.4041 During pregnancy and nursing, avoid most concentrated herbs unless your practitioner approves, and confirm any echinacea dose with your OB.2
Does echinacea interact with medications?
Yes, echinacea's interaction check is Moderate. It stimulates immunity and may work against immune-suppressing medicines such as tacrolimus, and in a study of 12 adults it sped the clearance of midazolam given by vein; the safety section gives what to do for each.236
Can echinacea help with cancer?
In mice, daily echinacea in the diet raised natural killer cells and lengthened life in aging mice and in mice with leukemia, but it hasn't been tested as a cancer treatment in people.22 For cancer support, my approach leads with diet, exercise, prayer, high-dose vitamin C, hyperthermia and nutrients like vitamin D, and the free Cancer Support Protocol lays it out.
Freshness & update log
November 12, 2026 — Rewrote the page in full under Dr. Axe's byline. The previous version, whose title promised nine benefits "from Colds to Cancer," called Echinacea purpurea the pale purple coneflower (that's E. pallida), described a mouse study as National Institutes of Health brain cancer research and quoted a call to use echinacea in place of conventional therapy, cited a guinea pig study as a clinical study of asthma, cited a cervical HPV study for vaginal yeast infections, called the summary of a Cochrane review a separate meta-analysis, said doses above 20 mg cancel echinacea's effect on anxiety, gave a 10 mg per kilogram dose from a broken link, said the NIH advises daily use, listed side effects of injected echinacea, and listed laxative, uveitis, ADHD and serious infections such as malaria and tuberculosis among its uses without trials in people. This version keeps its cold and flu, recurring infection, pain, inflammation, skin and mental health uses, each at its evidence level with each study's design and size; keeps its uses and forms and dosage sections; corrects the flu trial to name the elderberry juice in the drink; keeps cancer as one question answered from the mouse research; adds Dr. Axe's own approach, doses and traditional energetics, how echinacea works in your body, which species and part to use, an echinacea tea recipe, a Dr. Axe Score (7.6) with an interaction check (Moderate), three charts and a step diagram; and puts the allergy, autoimmune, pregnancy and children's cautions in one safety section, with 42 references.
June 2, 2026 — Previous version updated.
September 8, 2023 — Previous version published.
References
- Jawad M, Schoop R, Suter A, Klein P, Eccles R. Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial. Evid Based Complement Alternat Med. 2012;2012:841315. doi:10.1155/2012/841315. PMID:23024696 (PMC3457740)
- Axe J. Top 50 Healing Herbs & Essential Oils. DrAxe.com protocol. 2026 (Echinacea, Herb 06 of 30, p. 12: Best for, Top 5 Uses, How to Take It, How It Works, Traditional Energetics · Native American & Western; Your Natural Medicine Cabinet, cold & flu kit; Safety & interactions, immune-suppressing medications and pregnancy and nursing).
- Schapowal A, Klein P, Johnston SL. Echinacea reduces the risk of recurrent respiratory tract infections and complications: a meta-analysis of randomized controlled trials. Adv Ther. 2015;32(3):187-200. doi:10.1007/s12325-015-0194-4. PMID:25784510
- Rauš K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an Echinacea-Based Hot Drink Versus Oseltamivir in Influenza Treatment: A Randomized, Double-Blind, Double-Dummy, Multicenter, Noninferiority Clinical Trial. Curr Ther Res Clin Exp. 2015;77:66-72. doi:10.1016/j.curtheres.2015.04.001. PMID:26265958 (PMC4528044)
- Axe J, Cole W. Heal Your Cells. Avery; 2026 (Reversing Immune Age: Top Supplements and Herbs for Immune Health, #6 Echinacea, p. 327; echinacea among the traditional remedies of Indigenous North American tribes).
- Axe J. How to Prevent & Heal Cold & Flu Naturally (Foods, Supplements, & Herbs for Rapid Recovery). The Dr. Josh Axe Show. 2024 (astragalus and reishi for longer-term immune strengthening, at 13:36; echinacea's anti-inflammatory and antiviral properties and sore throats, at 14:02; elderberry and echinacea both shorten cold and flu time, at 14:22; the first 3 days, at 27:45; prevention with good sleep, exercise, time outdoors, vitamin C, zinc and vitamin D, at 33:41; fighting it fast and starting remedies when people in your house are sick, at 34:09; YouTube: https://www.youtube.com/watch?v=jw-cciZ5TTY).
- Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K. Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev. 2014;2014(2):CD000530. doi:10.1002/14651858.CD000530.pub3. PMID:24554461 (PMC4068831)
- Ogal M, Willcox M, Bauer R, Johnston SL, Kreft S, Booker A, et al. Safety of Oral Echinacea Preparations: Systematic Review and Meta-Analysis in the Context of Therapeutic Benefit. Planta Med. 2026. doi:10.1055/a-2992-1199. PMID:42951292
- Barnes J, Anderson LA, Gibbons S, Phillipson JD. Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt.,Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties. J Pharm Pharmacol. 2005;57(8):929-54. doi:10.1211/0022357056127. PMID:16102249
- National Institute of Child Health and Human Development. Echinacea. Drugs and Lactation Database (LactMed). Bethesda (MD); 2006-, updated 2024 Oct 15. PMID:30000869
- Pleschka S, Stein M, Schoop R, Hudson JB. Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV). Virol J. 2009;6:197. doi:10.1186/1743-422X-6-197. PMID:19912623 (PMC2785784)
- European Medicines Agency, Committee on Herbal Medicinal Products. Echinaceae purpureae herba (purple coneflower herb): EU herbal monograph and summary for the public.
- Liu R, Caram-Salas NL, Li W, Wang L, Arnason JT, Harris CS. Interactions of Echinacea spp. Root Extracts and Alkylamides With the Endocannabinoid System and Peripheral Inflammatory Pain. Front Pharmacol. 2021;12:651292. doi:10.3389/fphar.2021.651292. PMID:33986678 (PMC8111300)
- Huntley AL, Thompson Coon J, Ernst E. The safety of herbal medicinal products derived from Echinacea species: a systematic review. Drug Saf. 2005;28(5):387-400. doi:10.2165/00002018-200528050-00003. PMID:15853441
- Shah SA, Sander S, White CM, Rinaldi M, Coleman CI. Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis. Lancet Infect Dis. 2007;7(7):473-80. doi:10.1016/S1473-3099(07)70160-3. PMID:17597571 (PMC7106401)
- Schapowal A, Berger D, Klein P, Suter A. Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. Eur J Med Res. 2009;14(9):406-12. doi:10.1186/2047-783x-14-9-406. PMID:19748859 (PMC3351972)
- Haller J, Krecsak L, Zámbori J. Double-blind placebo controlled trial of the anxiolytic effects of a standardized Echinacea extract. Phytother Res. 2020;34(3):660-668. doi:10.1002/ptr.6558. PMID:31876052
- Lopresti AL, Smith SJ. An investigation into the anxiety-relieving and mood-enhancing effects of Echinacea angustifolia (EP107™): A randomised, double-blind, placebo-controlled study. J Affect Disord. 2021;293:229-237. doi:10.1016/j.jad.2021.06.054. PMID:34217960
- Yotsawimonwat S, Rattanadechsakul J, Rattanadechsakul P, Okonogi S. Skin improvement and stability of Echinacea purpurea dermatological formulations. Int J Cosmet Sci. 2010;32(5):340-6. doi:10.1111/j.1468-2494.2009.00559.x. PMID:20384903
- Oláh A, Szabó-Papp J, Soeberdt M, Knie U, Dähnhardt-Pfeiffer S, Abels C, et al. Echinacea purpurea-derived alkylamides exhibit potent anti-inflammatory effects and alleviate clinical symptoms of atopic eczema. J Dermatol Sci. 2017;88(1):67-77. doi:10.1016/j.jdermsci.2017.05.015. PMID:28610718
- Raduner S, Majewska A, Chen JZ, Xie XQ, Hamon J, Faller B, et al. Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects. J Biol Chem. 2006;281(20):14192-206. doi:10.1074/jbc.M601074200. PMID:16547349
- Miller SC. Echinacea: a miracle herb against aging and cancer? Evidence in vivo in mice. Evid Based Complement Alternat Med. 2005;2(3):309-14. doi:10.1093/ecam/neh118. PMID:16136209 (PMC1193558)
- Woelkart K, Koidl C, Grisold A, Gangemi JD, Turner RB, Marth E, et al. Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans. J Clin Pharmacol. 2005;45(6):683-9. doi:10.1177/0091270004273493. PMID:15901750
- Gertsch J, Schoop R, Kuenzle U, Suter A. Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways. FEBS Lett. 2004;577(3):563-9. doi:10.1016/j.febslet.2004.10.064. PMID:15556647
- Sharma M, Schoop R, Hudson JB. Echinacea as an antiinflammatory agent: the influence of physiologically relevant parameters. Phytother Res. 2009;23(6):863-7. doi:10.1002/ptr.2714. PMID:19107735
- Vimalanathan S, Schoop R, Suter A, Hudson J. Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells. Virus Res. 2017;233:51-59. doi:10.1016/j.virusres.2017.03.006. PMID:28279802
- David S, Cunningham R. Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis. Complement Ther Med. 2019;44:18-26. doi:10.1016/j.ctim.2019.03.011. PMID:31126553
- Gancitano G, Mucci N, Stange R, Ogal M, Vimalanathan S, Sreya M, et al. Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA). Antibiotics (Basel). 2024;13(4):364. doi:10.3390/antibiotics13040364. PMID:38667040 (PMC11047471)
- Ogal M, Johnston SL, Klein P, Schoop R. Echinacea reduces antibiotic usage in children through respiratory tract infection prevention: a randomized, blinded, controlled clinical trial. Eur J Med Res. 2021;26(1):33. doi:10.1186/s40001-021-00499-6. PMID:33832544 (PMC8028575)
- Lindenmuth GF, Lindenmuth EB. The efficacy of echinacea compound herbal tea preparation on the severity and duration of upper respiratory and flu symptoms: a randomized, double-blind placebo-controlled study. J Altern Complement Med. 2000;6(4):327-34. doi:10.1089/10755530050120691. PMID:10976979
- Barrett B, Brown R, Rakel D, Mundt M, Bone K, Barlow S, et al. Echinacea for treating the common cold: a randomized trial. Ann Intern Med. 2010;153(12):769-77. doi:10.7326/0003-4819-153-12-201012210-00003. PMID:21173411 (PMC3056276)
- Turner RB, Bauer R, Woelkart K, Hulsey TC, Gangemi JD. An evaluation of Echinacea angustifolia in experimental rhinovirus infections. N Engl J Med. 2005;353(4):341-8. doi:10.1056/NEJMoa044441. PMID:16049208
- Axe J. The SHOCKING Science of Daily Red Light and Sauna Use. The Dr. Josh Axe Show. 2025 (the front end of a cold or flu as the most important time to act, and elderberry, echinacea and vitamin D with hardly any symptoms, at 43:21; YouTube: https://www.youtube.com/watch?v=pt2mxcJYBEM).
- Axe J. What Happens In Your Body If You Eat Honey Every Day? The Dr. Josh Axe Show. 2025 (sore throat coming on: Manuka honey, propolis, "lots of echinacea," thyme tea, at 22:19).
- Axe J. Ancient Remedies: Secrets to Healing with Herbs, Essential Oils, CBD, and the Most Powerful Natural Medicine in History. Little, Brown Spark; 2021 (Prescriptions for 70+ Conditions: Common cold, top 5 ancient prescriptions, #1 echinacea, p. 231).
- Gorski JC, Huang SM, Pinto A, Hamman MA, Hilligoss JK, Zaheer NA, et al. The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo. Clin Pharmacol Ther. 2004;75(1):89-100. doi:10.1016/j.clpt.2003.09.013. PMID:14749695
- Gurley BJ, Gardner SF, Hubbard MA, Williams DK, Gentry WB, Carrier J, et al. In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto. Clin Pharmacol Ther. 2004;76(5):428-40. doi:10.1016/j.clpt.2004.07.007. PMID:15536458
- Mullins RJ, Heddle R. Adverse reactions associated with echinacea: the Australian experience. Ann Allergy Asthma Immunol. 2002;88(1):42-51. doi:10.1016/S1081-1206(10)63591-0. PMID:11814277
- Lee AN, Werth VP. Activation of autoimmunity following use of immunostimulatory herbal supplements. Arch Dermatol. 2004;140(6):723-7. doi:10.1001/archderm.140.6.723. PMID:15210464
- Gallo M, Sarkar M, Au W, Pietrzak K, Comas B, Smith M, et al. Pregnancy outcome following gestational exposure to echinacea: a prospective controlled study. Arch Intern Med. 2000;160(20):3141-3. doi:10.1001/archinte.160.20.3141. PMID:11074744
- Heitmann K, Havnen GC, Holst L, Nordeng H. Pregnancy outcomes after prenatal exposure to echinacea: the Norwegian Mother and Child Cohort Study. Eur J Clin Pharmacol. 2016;72(5):623-30. doi:10.1007/s00228-016-2021-5. PMID:26895223
- Taylor JA, Weber W, Standish L, Quinn H, Goesling J, McGann M, et al. Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled trial. JAMA. 2003;290(21):2824-30. doi:10.1001/jama.290.21.2824. PMID:14657066
This article is for educational purposes. See our medical disclaimer.


