Seed Oils: Are They Bad for You? What the Research Really Says

The quick best-and-worst, before we go deep:

Want the full picture? Jump to the 16-oil comparison chart or the ranked best oils.

Few nutrition topics have gotten as heated as seed oils. One side calls them "the hateful eight" and blames them for nearly every modern disease. The other says that's misinformation and that these oils are heart-healthy. As a physician who reads the actual studies, I'll tell you what's true: the answer lives in the nuance both camps skip over.

In this guide I'll walk through how seed oils are really made, what the research shows when you put them head-to-head with saturated fat, why thoughtful experts still disagree, whether they truly drive inflammation, and where the genuine concerns lie. Then I'll give you my ranking — the oils I cook with and recommend, including some healthy cold-pressed seed oils most people overlook — plus a full comparison chart of 16 oils so you can decide for yourself.

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What are seed oils?

"Seed oil" simply means an oil pressed from a seed rather than from a fruit (like olives or avocados) or an animal. The ones at the center of the debate are sometimes called the "hateful eight": canola (rapeseed), soybean, corn, cottonseed, sunflower, safflower, grapeseed, and rice bran oil. What unites them is that they're rich in omega-6 linoleic acid and almost always industrially refined.

But here's a distinction that gets lost in the noise: a seed oil isn't automatically a refined oil. Some of the most nutritious oils in the world — flaxseed, cold-pressed sesame, hemp, pumpkin seed, black seed — are also technically seed oils, just minimally processed. The real dividing line isn't "seed versus not." It's how much processing the oil went through and how you use it (see the healthy cold-pressed seed oils below).

Seed oils list: which oils count as a seed oil?

The most common refined seed oils are canola, soybean, corn, cottonseed, sunflower, safflower, grapeseed, and rice bran oil — plus peanut oil, which behaves like one. Sesame, flaxseed, walnut, hemp, pumpkin seed, and black seed are also seed oils, but when cold-pressed and unrefined they're a different, more nutritious category. Olive and avocado oils are not seed oils — they're fruit oils.

How seed oils are made: from seed to bottle

Most supermarket seed oils are made by crushing the seeds, heating them, and washing them with a petroleum solvent (hexane) to squeeze out every drop of oil. The crude oil is then degummed, treated with caustic soda, bleached with clay, and deodorized with steam at around 400–500°F. This strips out the natural antioxidants, color, and smell — and can create trace trans fats and oxidation products along the way.

This is the part most people never see, and it's the heart of the concern. Pressing an olive or an avocado is mechanical — you crush the fruit and the oil comes out. Refining a seed oil is an industrial, multi-step chemical process:

How an industrial seed oil is made

The contrast: extra-virgin olive oil and cold-pressed avocado oil skip all of this — they're simply pressed, so they keep their polyphenols, vitamin E, and natural antioxidants. That difference in processing, more than the word "seed," is what matters for your cellular health.

None of this means a refined oil is instantly toxic. But it does mean the finished product is a fundamentally different food than a cold-pressed oil: stripped of protective antioxidants, higher in oxidation-prone polyunsaturated fat, and primed to degrade further when you heat it again at home or when a restaurant reuses it in a fryer.

The types of fat, explained (and why it matters)

All cooking fats are a blend of three types: saturated (no double bonds, very stable), monounsaturated (one double bond, stable — the main fat in olive and avocado oil), and polyunsaturated (two or more double bonds, easily oxidized — the main fat in seed oils). The more double bonds, the more prone a fat is to oxidizing when exposed to heat, light, and air. That chemistry is why seed oils, which are mostly polyunsaturated, are the ones that degrade with frying.

To cut through the noise, you need one idea: the number of double bonds in a fat determines how fragile it is.

• Saturated fat (SFA) — no double bonds, so it's the most stable and heat-resistant. Found in butter, coconut oil, tallow. Its downside is that it raises LDL cholesterol.

• Monounsaturated fat (MUFA) — one double bond; stable and well-tolerated by heat. The dominant fat in extra-virgin olive oil and avocado oil, and the one with the best track record.

• Polyunsaturated fat (PUFA) — two or more double bonds, which makes it the most prone to oxidation. This is the main fat in seed oils, split into omega-6 (mostly linoleic acid) and omega-3.

Within the polyunsaturated family, balance matters. Over the 20th century, as seed oils spread through the food supply, Americans' intake of omega-6 linoleic acid climbed dramatically while omega-3 stayed flat.15 Our ancestors likely ate omega-6 and omega-3 in roughly a 1:1 to 4:1 ratio; the modern Western diet runs closer to 15:1 or 20:1.1920 Whether that imbalance directly causes disease is debated — more on that below — but one practical lever stands out: raising your omega-3 intake (from fatty fish, fish oil, flax, and walnuts) may matter more than fixating on omega-6 alone.

Seed oils vs. saturated fat: what the research shows

This is where it pays to be fair to both sides, because the science cuts both ways.

The case for seed oils (the mainstream/AHA view)

In its 2017 Presidential Advisory, the American Heart Association concluded that randomized trials lowering saturated fat and replacing it with polyunsaturated vegetable oil reduced cardiovascular disease by about 30%.1 That advisory leaned heavily on a 2010 meta-analysis of randomized controlled trials finding that swapping polyunsaturated fat for saturated fat reduced coronary heart-disease events.2 A large Cochrane review similarly found that reducing saturated fat modestly lowers the risk of cardiovascular events.9

The biomarker data go further. People with higher blood levels of linoleic acid tend to have modestly lower rates of death from all causes, cardiovascular disease, and cancer.5 And in one of the largest analyses on the question — a pooled study of 39,740 adults across 20 cohorts — those with the highest linoleic acid biomarker were about 35% less likely to develop type 2 diabetes, with no harm seen from arachidonic acid.26 That's a serious body of evidence the skeptic camp often waves away, and it's the main reason I tell patients not to panic over linoleic acid from whole foods.

The case against (the skeptic view)

But the picture gets complicated fast. Two of the most rigorous trials ever done on this question were buried for decades. When Dr. Christopher Ramsden and colleagues recovered the lost data, the results were striking. In the Sydney Diet Heart Study, men who replaced saturated fat with omega-6 linoleic acid (from safflower oil) lowered their cholesterol — but had higher rates of death from heart disease and all causes.3 In the Minnesota Coronary Experiment, linoleic acid from corn oil dropped cholesterol by nearly 14%, yet brought no reduction in heart attacks or deaths — and for participants over 65, each drop in cholesterol was paradoxically linked to higher mortality.4 A meta-analysis combining five such trials found these cholesterol-lowering swaps produced no benefit for coronary or all-cause mortality.4

This sits alongside other inconvenient findings: a 2010 meta-analysis of prospective studies concluded that saturated fat itself is not significantly associated with cardiovascular disease,6 a 2015 BMJ review found saturated fat unlinked to all-cause mortality (while trans fat clearly was),7 and a 2014 analysis in Annals of Internal Medicine found the fatty-acid evidence didn't clearly support the conventional fat guidelines.8

Why the research conflicts (and what the studies miss)

Smart people disagree about seed oils partly because the studies have real blind spots. Olive oil is frequently lumped in with seed oils as "vegetable oil," inflating the whole category. Many trials compare seed oils to ordinary (not grass-fed) butter, which is nutritionally weaker. Total calories and overall diet are often poorly controlled. And the biggest lever — raising omega-3 intake — is frequently ignored. Once you see these gaps, the contradictions make more sense.

Four issues explain most of the confusion:

1. Olive oil gets counted as a "vegetable oil"

Many large studies don't test seed oils on their own — they lump them together with olive oil into a single "vegetable oil" or "plant-based oil" category. A widely covered 2025 study in JAMA Internal Medicine followed more than 200,000 adults and found that replacing butter with "plant-based oils" was associated with about a 17% lower risk of dying.10 The headlines said "plant oils beat butter." But the authors' own words show the benefit was driven "especially" by olive, soybean, and canola.10 Olive oil — which is not a seed oil — was folded right into the group doing the heavy lifting. Because olive oil's own evidence is so strong (in the PREDIMED trial, a Mediterranean diet supplemented with extra-virgin olive oil lowered a combined measure of heart attack, stroke and cardiovascular death by about 30%),1113 a meaningful share of the "vegetable oils are healthy" signal is really an olive oil signal. Isolate seed oils, and their edge looks smaller.

2. The butter in these studies usually isn't grass-fed

Many "seed oil beats butter" studies compare refined oils to ordinary, conventional butter — and that's not a fair fight. Grass-fed butter from pasture-raised cows is nutritionally richer: pasture feeding raises omega-3 fats, conjugated linoleic acid (CLA), vitamin K2, beta-carotene, and other fat-soluble vitamins, while lowering omega-6.27 When a study pits a refined seed oil against low-quality grain-fed butter, it isn't really testing "seed oil vs. saturated fat" so much as "one industrial product vs. another." A traditional, grass-fed fat may perform very differently — and most trials never test it.

3. Calories and overall diet are often poorly controlled

All fats are calorie-dense, and refined seed oils ride along in fried foods, chips, dressings, and packaged snacks. In real-world studies, it's hard to separate the oil from the ultra-processed food it arrives in — or from simple overeating. When total calories aren't tightly controlled, a "seed oil" association can really be a "junk-food, too-many-calories" association in disguise. That's not a reason to dismiss the data, but it is a reason to read it carefully.

4. The real lever is omega-3, not just omega-6

Here's the point I keep coming back to with patients: the modern problem isn't only that we eat too much omega-6 — it's that we eat too little omega-3 to balance it.1920 A meta-analysis even found that PUFA interventions raising omega-6 alone behaved differently from those that also raised omega-3, hinting that much of the benefit comes from omega-3.17 So rather than fight about every gram of linoleic acid, the higher-leverage move is to raise omega-3 from fatty fish, fish oil, flax, and walnuts. Fix the ratio from the omega-3 side, and a lot of the omega-6 worry takes care of itself.

Do seed oils cause inflammation? The omega-6 debate

The theory goes like this: omega-6 linoleic acid is a precursor to arachidonic acid, which makes pro-inflammatory signaling molecules — so more omega-6 should mean more inflammation. It's a tidy story. The problem is that, when tested in humans, it largely doesn't hold. A systematic review of randomized controlled trials concluded that adding linoleic acid to the diet does not measurably raise blood markers of inflammation in healthy adults,16 because the conversion of linoleic acid to arachidonic acid is minimal. This is one place the seed-oil critics get out over their skis, and it's worth saying plainly.

That said, the mainstream doesn't get to declare total victory either. The omega-6:omega-3 ratio still tracks with obesity and chronic disease,19 omega-6-only swaps behave differently from mixed PUFA,17 and balanced reviews call this an area of real controversy rather than a closed case.18 My read: linoleic acid from whole foods — nuts, seeds, whole grains — isn't something to fear, and the "omega-6 is inflammatory" slogan is too simple. The legitimate concern isn't the molecule in an almond. It's the sheer volume of refined, oxidation-prone omega-6 we now get from processed food, and what happens to these oils under heat.

The real problem: oxidation, your cells & ultra-processed food

Because polyunsaturated fats carry multiple fragile double bonds, they oxidize readily when exposed to heat, light, and air. When you fry with them — and especially when oil is reused, as it is in many restaurants — they break down into a soup of secondary oxidation products: aldehydes, including the well-studied toxins 4-hydroxynonenal (4-HNE) from omega-6 oils, along with malondialdehyde and 2,4-decadienal.2122 These compounds rise with temperature and repeated heating, and researchers have flagged them as a reason to rethink using PUFA-rich oils for high-heat frying.21 Refining itself, with its bleaching and high-heat deodorizing, already strips the protective antioxidants that would otherwise slow this process.21

From a cellular-health perspective, the concern isn't simply "omega-6." The concern is damaged fat. Oxidized oils can create compounds that stress cell membranes, mitochondria, blood vessels, and inflammatory signaling pathways. Your cell membranes are partly built from the fats you eat — which is exactly why I want people choosing clean, stable, whole-food fats most of the time. This isn't about claiming seed oils single-handedly cause disease; it's about oxidative stress and giving your cells the best raw materials to work with.

There's a second, subtler issue. Seed oils are the dominant fat in ultra-processed foods — the packaged snacks, fried fast food, and shelf-stable baked goods that now make up a large share of American calories. When studies link high seed-oil intake to poor health, it's often impossible to separate the oil from the ultra-processed package it arrives in. The oil may be partly a marker of a junk-food diet as much as a cause. Either way, the practical lesson is the same: the oil deep-fried in a fast-food kitchen or baked into a cookie is the one to minimize.

What I do in my own kitchen

In my home, I don't obsess over trace seed oils, but I don't choose them when better fats are available. My everyday foundation is extra-virgin olive oil, avocado oil for higher heat, and small amounts of grass-fed ghee, coconut oil, or tallow when a recipe calls for it — plus cold-pressed flax or sesame to finish. The bigger principle: choose fats closer to the way they're found in nature.

People ask what's on my counter, so here it is. My default bottle is extra-virgin olive oil — for dressings, drizzling, and most cooking. For higher-heat searing and roasting I reach for avocado oil. When a recipe wants a richer or more heat-stable fat, I'll use small amounts of grass-fed ghee, coconut oil, or tallow. And for flavor and a quiet omega-3 boost, I'll finish dishes with cold-pressed flaxseed or toasted sesame oil. I keep oils in dark glass, away from heat, and I don't deep-fry at home.

The bigger principle is this: choose fats that are closer to the way God made them — less refined, less oxidized, and more connected to whole foods. That single idea — whole-food fats first — quietly settles ninety percent of the seed-oil question without any fear or fuss.

The best cooking oils, ranked

Healthy cold-pressed seed oils most people overlook

Not every seed oil is a refined, omega-6-heavy industrial product. Cold-pressed, unrefined flaxseed, sesame, hemp, pumpkin seed, and black seed oils keep their natural antioxidants and can be beneficial — several are rich in omega-3. The catch: these are delicate finishing oils, not high-heat cooking oils. Use them raw or at low heat, store them cold, and use them up quickly.

This is the nuance the "all seed oils are poison" crowd misses entirely. When a seed oil is cold-pressed and unrefined, it's a completely different food than a refined, deodorized industrial oil. Here are five worth knowing:

The seed oils to limit (and why)

Ranked roughly from most worth limiting to least, based on omega-6 load and how they're typically used:

• Cottonseed oil — high omega-6, often heavily refined, common in fried and packaged foods.

• Corn oil — very high omega-6 with a lopsided omega-6:3 ratio; a fryer staple.

• Soybean oil — the most-consumed oil in the U.S. food supply and the default in ultra-processed food.

• Regular sunflower & safflower oil — among the highest in polyunsaturated fat, so the most oxidation-prone when heated (high-oleic versions are more stable).

• Grapeseed oil — marketed as gourmet but very high in omega-6 and highly refined.

• Rice bran & peanut oil — better than the above, but still refined and best used sparingly.

• Canola oil — the least problematic seed oil: low in saturated fat, ~2:1 omega-6:3. Prefer cold/expeller-pressed, and still not your main fat.

How to read labels for seed oils

On packaged foods, scan the ingredient list for these terms: soybean oil, canola oil, corn oil, cottonseed oil, sunflower oil, safflower oil, "vegetable oil," and anything that says hydrogenated or partially hydrogenated oil. The last two are the real red flag — they can contain trans fats. "Vegetable oil" almost always means refined seed oil, not olive or avocado.

Most of the refined seed oil people eat isn't poured from a bottle at home — it's hidden in packaged and restaurant food. When you turn over a label, these are the words to look for:

• Soybean oil, canola oil, corn oil, cottonseed oil, sunflower oil, safflower oil — the common refined seed oils.

• "Vegetable oil" — a vague blend that's usually soybean and/or canola; rarely anything you'd choose on purpose.

• Hydrogenated or partially hydrogenated oil — the biggest red flag, since these can contain heart-harming trans fats.

• Extra-virgin olive oil, avocado oil, coconut oil, grass-fed butter — the ingredients you want to see.

None of this means one cracker with sunflower oil will hurt you. But when seed oils show up in the first few ingredients of foods you eat every day, that's the pattern worth changing.

Are high-oleic seed oils different?

Yes, somewhat. High-oleic sunflower, safflower, and canola oils are bred to be higher in stable monounsaturated fat and lower in fragile polyunsaturated fat, so they resist oxidation and heat better than the regular versions. That makes them a real improvement — but they're still usually refined, so they're not a first choice over extra-virgin olive or avocado oil.

You'll increasingly see "high-oleic" on labels, and it's a genuine upgrade over the standard versions. By shifting the fat profile toward oleic acid (the same monounsaturated fat that dominates olive oil), these oils become more heat-stable and less prone to forming oxidation products. If a packaged food has to use a seed oil, high-oleic is the better version to see.

That said, "better than regular sunflower oil" is a low bar. High-oleic oils are still typically refined and stripped of the antioxidants you'd get from a cold-pressed oil, and they don't carry the human-research track record of olive or avocado oil. I treat them as an acceptable backup — not as a reason to displace the fruit oils at the top of the list.

Who should be more cautious with seed oils?

This isn't about fear — it's about who has the most to gain from being deliberate. I'd encourage extra intentionality if you:

• Eat a lot of fried or ultra-processed food, where oxidized seed oils concentrate.

• Have metabolic issues like insulin resistance, prediabetes, or fatty liver.

• Live with high oxidative stress or an inflammatory condition.

• Have elevated LDL or established heart-disease risk.

• Get very little omega-3 — the imbalance matters more when omega-3 is low.

For everyone else, the message stays calm and practical: favor whole-food fats, cut the deep-fried and ultra-processed foods, and don't lose sleep over trace seed oil in an otherwise real-food diet.

Cooking oil comparison chart

Across 16 common cooking fats, the pattern is clear: olive and avocado oil are mostly stable monounsaturated fat with minimal processing; coconut, butter, ghee, and tallow are saturated and stable but raise LDL; and refined seed oils (soybean, corn, sunflower, safflower, grapeseed, cottonseed) are mostly oxidation-prone omega-6 polyunsaturated fat. Use the chart to match the fat to the job and to your goals.

Approximate fat composition and properties. (Percentages are rounded and vary by source and variety; high-oleic versions of sunflower, safflower, and canola are more monounsaturated and more heat-stable than the regular versions shown.)

Saturated (stable) · Monounsaturated (stable) · Polyunsaturated (oxidation-prone)

Smoke points are approximate and depend on refinement and freshness. "My rating" reflects my clinical preference based on processing, fat stability, omega balance, and the weight of the evidence — not a claim that any single oil causes or cures disease. Only extra-virgin olive oil earns my top "best" rating.

Seed oils: frequently asked questions

The bottom line

References

1. Sacks FM, Lichtenstein AH, Wu JHY, et al. Dietary fats and cardiovascular disease: a presidential advisory from the American Heart Association. Circulation. 2017;136(10):e1-e24. doi:10.1161/CIR.0000000000000510
2. Mozaffarian D, Micha R, Wallace S. Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Med. 2010;7(3):e1000252. doi:10.1371/journal.pmed.1000252
3. Ramsden CE, Zamora D, Leelarthaepin B, et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ. 2013;346:e8707. PMID:23386268
4. Ramsden CE, Zamora D, Majchrzak-Hong S, et al. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). BMJ. 2016;353:i1246. doi:10.1136/bmj.i1246
5. Li J, Guasch-Ferré M, Li Y, Hu FB. Dietary intake and biomarkers of linoleic acid and mortality: systematic review and meta-analysis of prospective cohort studies. Am J Clin Nutr. 2020;112(1):150-167. PMID:32020162
6. Siri-Tarino PW, Sun Q, Hu FB, Krauss RM. Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr. 2010;91(3):535-546. PMID:20071648
7. de Souza RJ, Mente A, Maroleanu A, et al. Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis. BMJ. 2015;351:h3978. doi:10.1136/bmj.h3978
8. Chowdhury R, Warnakula S, Kunutsor S, et al. Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. Ann Intern Med. 2014;160(6):398-406. doi:10.7326/M13-1788
9. Hooper L, Martin N, Jimoh OF, et al. Reduction in saturated fat intake for cardiovascular disease. Cochrane Database Syst Rev. 2020;(8):CD011737. doi:10.1002/14651858.CD011737.pub3
10. Zhang Y, Chadaideh KS, Li Y, et al. Butter and plant-based oils intake and mortality. JAMA Intern Med. 2025;185(5):549-560. PMID:40048719
11. Estruch R, Ros E, Salas-Salvado J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts (PREDIMED). N Engl J Med. 2018;378:e34. doi:10.1056/NEJMoa1800389
12. Guasch-Ferre M, Hu FB, Martinez-Gonzalez MA, et al. Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED study. BMC Med. 2014;12:78. PMID:24886626
13. Guasch-Ferre M, Li Y, Willett WC, et al. Consumption of olive oil and risk of total and cause-specific mortality among U.S. adults. J Am Coll Cardiol. 2022;79(2):101-112. PMID:35027106
14. Neelakantan N, Seah JYH, van Dam RM. The effect of coconut oil consumption on cardiovascular risk factors: a systematic review and meta-analysis of clinical trials. Circulation. 2020;141(10):803-814. doi:10.1161/CIRCULATIONAHA.119.043052
15. Blasbalg TL, Hibbeln JR, Ramsden CE, et al. Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. Am J Clin Nutr. 2011;93(5):950-962. doi:10.3945/ajcn.110.006643
16. Johnson GH, Fritsche K. Effect of dietary linoleic acid on markers of inflammation in healthy persons: a systematic review of randomized controlled trials. J Acad Nutr Diet. 2012;112(7):1029-1041. doi:10.1016/j.jand.2012.03.029
17. Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM. n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of RCTs. Br J Nutr. 2010;104(11):1586-1600. doi:10.1017/S0007114510004010
18. Maki KC, Eren F, Cassens ME, et al. Omega-6 polyunsaturated fatty acids and cardiometabolic health: current evidence, controversies, and research gaps. Adv Nutr. 2018;9(6):688-700. doi:10.1093/advances/nmy038
19. Simopoulos AP. An increase in the omega-6/omega-3 fatty acid ratio increases the risk for obesity. Nutrients. 2016;8(3):128. PMID:26950145
20. Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother. 2002;56(8):365-379. doi:10.1016/S0753-3322(02)00253-6
21. Grootveld M. Evidence-based challenges to the continued recommendation and use of peroxidatively-susceptible polyunsaturated fatty acid-rich culinary oils for high-temperature frying practises: experimental revelations focused on toxic aldehydic lipid oxidation products. Front Nutr. 2022;8:711640. doi:10.3389/fnut.2021.711640
22. Zhuang Y, Dong J, He X, et al. Impact of heating temperature and fatty acid type on the formation of lipid oxidation products during thermal processing. Front Nutr. 2022;9:913297. doi:10.3389/fnut.2022.913297
23. Hamednia S, Shouhani Z, Tavakol S, et al. Effects of avocado products on cardiovascular risk factors in adults: a GRADE-assessed systematic review and meta-analysis. Food Sci Nutr. 2025;13(7):e70547. PMID:40612140
24. Vahedi H, Atefi M, Ghanbarian M, et al. Sesame oil improves blood lipid profile in patients with metabolic disease: a systematic review and meta-analysis of randomized controlled trials. Nutr Food Sci. 2025;55(5):868-891. doi:10.1108/NFS-12-2024-0401
25. Guasch-Ferre M, Liu G, Li Y, et al. Olive oil consumption and cardiovascular risk in U.S. adults. J Am Coll Cardiol. 2020;75:1729-1739. doi:10.1016/j.jacc.2020.02.036
26. Wu JHY, Marklund M, Imamura F, et al. Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39,740 adults from 20 prospective cohort studies. Lancet Diabetes Endocrinol. 2017;5(12):965-974. PMID:29032079
27. Alothman M, Hogan SA, Hennessy D, et al. The "grass-fed" milk story: understanding the impact of pasture feeding on the composition and quality of bovine milk. Foods. 2019;8(8):350. PMID:31426489
28. Derosa G, D'Angelo A, Maffioli P, Cucinella L, Nappi RE. The use of Nigella sativa in cardiometabolic diseases. Biomedicines. 2024;12(2):405. PMID:38398007
29. Farinon B, Molinari R, Costantini L, Merendino N. The seed of industrial hemp (Cannabis sativa L.): nutritional quality and potential functionality for human health and nutrition. Nutrients. 2020;12(7):1935. PMID:32610691

Dr. Josh Axe, DC, DNM, CNS

Doctor of Natural Medicine · Founder, DrAxe.com

Dr. Axe is a certified doctor of natural medicine, clinical nutritionist, and multiple New York Times bestselling author. He has spent 20+ years in clinical practice helping people heal at the root cause and founded one of the most-visited natural-health platforms in the world.

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This article is for educational purposes. See our medical disclaimer.