Herbs & Adaptogens · Adaptogens

Maca Root Powder: Benefits, Nutrition Facts, Dosage & Side Effects

What a spoonful of maca powder holds, what the human trials show for desire, menopause and mood, what they found about hormone levels, and how to choose, dose and use it.

Meet the Medical Advisory Board
Evidence-based52 sources citedUpdated October 1, 2026
Published Oct 1, 2026Last updated Oct 1, 2026Editorial policyMedical review policyFact-checking policy
A glass bowl of tan maca powder beside a wooden spoon and two whole yellow maca roots, with baked cookies on a wooden plate behind them
Maca (Lepidium meyenii) is a cruciferous root from Peru's central Andes, dried and milled into the powder sold today.
The Dr. Axe Score™
7.4/10
Overall Dr. Axe Score · Maca Root Powder

Maca earns its score from two places: a long Andean food tradition, and a cluster of placebo-controlled trials on desire, sexual function, menopause symptom scores and mood.

Scientific Evidence
6.2/10
More than 20 human studies, the largest starting with 193 people.
Traditional Medicine
8.4/10
Centuries of Andean use as a food and a vitality and fertility tonic, within one regional tradition.
Clinical Effectiveness
6.8/10
Our judgment: modest gains on desire, sexual function, menopause scores and mood.
Safety
8.6/10
Well tolerated in trials of up to about four months; the deduction reflects lead and cadmium from mining-area soils and thin long-term data.
Why this score?
Why Maca Root Powder scores 7.4 / 10
  • In 57 healthy men, 1.5 or 3 grams a day of gelatinized maca improved desire from week 8.[16][2]
  • How the score works: Scientific Evidence rates human, animal and lab research; Traditional Medicine, how long and widely it has been used; Clinical Effectiveness, the team's judgment of how well it works in human trials, informed by Dr. Axe's clinical experience; Safety, side effects weighed by dose, form and who is taking it. Interactions get their own rating in the Interaction check. These are editorial judgments, not clinical measurements.
  • Weighting: Evidence 30% · Traditional Medicine 25% · Clinical Effectiveness 25% · Safety 20% (6.2×0.30 + 8.4×0.25 + 6.8×0.25 + 8.6×0.20 = 7.38, shown as 7.4).
  • Interaction check: Low; the details are in the side effects section. Interactions are rated separately and don't change the score.

It stops short of a higher number because the trials are small and brief, and fertility and sports results are mixed.

A transparent, weighted index built for supplements. See how it’s calculated →

Interaction check: Low. Few interactions have been reported for maca, and human evidence is limited.17 One case report linked maca taken with the antidepressant mianserin to restless legs, though a single report can't show how often that happens.17 Blood pressure fell on maca in two placebo-controlled trials in women around menopause843 and didn't differ from placebo in a 12-week trial in Peru,25 while in a 90-day placebo-controlled trial in people with metabolic syndrome, diastolic pressure rose moderately in volunteers taking 0.6 grams of maca a day.50 If you take an antidepressant or blood pressure medication, tell your prescriber and watch for new symptoms or unusual readings. See who should be careful. Interactions are rated separately and don't change the score.

Dr. Josh Axe Vitamin Advisor · 4–5 questions

Which supplements belong in your top 5?

What's your biggest goal right now?

Maca at a glance

Maca is the dried root of Lepidium meyenii, a cruciferous plant Andean families have eaten for 1,300 to 2,000 years, and its best human evidence is for sexual desire, sexual function and menopausal symptom scores.123 A tablespoon (about 8 grams) has roughly 27 calories, 6 grams of carbohydrate and 1.1 grams of protein.45 Maca doesn't supply hormones of its own; in most placebo-controlled trials that measured them, sex hormones didn't rise significantly, and in reports from a maca supplier's research group in women around menopause, estradiol rose from the body's own production.763712

  • Amount: most trials used 1.5 to 3.5 grams a day of powder or gelatinized powder, often about 3 grams13
  • Timing: most trials measured their main results at six weeks to four months1216

Maca is a knobby, radish-like root from Peru's high plateaus, and in the Andes it has been food first for centuries. Families there cook it, bake it, stir it into porridge and ferment it into a drink, and they've prized it as a tonic for vitality and fertility in people and livestock.1

I give that kind of long, consistent use real weight. Maca is also a crucifer, a relative of cabbage and radish,4 and I often favor gently cooked crucifers over raw ones because they're easier on the gut. Gelatinized maca is the modern, cooked version. In the research, maca behaves like a mild tonic: desire, menopause symptoms and mood improved in several placebo-controlled trials.

In perimenopause? Open the free Perimenopause & Menopause protocol.

Did you know?

  • Maca's traditional home is Peru's central Andes, where it grows at 4,000 to 4,500 meters (about 13,100 to 14,800 feet).15

  • Since 2005, Peru has counted maca among its seven national "flag products."15

  • In counted Peruvian harvests, more than half the roots were yellow; black made up only 6% to 10%.4

Advertisement20% off Ancient Nutrition Multi Collagen Protein, code MCP20

What is maca?

Quick answer

Maca is the dried root of Lepidium meyenii, a cruciferous plant grown at 4,000 to 4,500 meters in Peru's central Andes.15 It's sold as dried powder, pressure-cooked (gelatinized) powder or concentrated extract, and its signature compounds, macamides, have been identified only in maca.14

You'll find maca in yellow, red and black, and the colors differ more in their plant compounds than in their nutrition.419 The form matters even more: in one Peruvian trial, each 3-gram dose of extract came from about 20 grams of dried root, so check which form a study used.25

A short history of maca

Andean people have grown maca for 1,300 to 2,000 years as a staple food and a tonic for vitality and fertility.1 It first appears in written records in the 17th century.20 Local custom eats it dried and boiled rather than fresh, and a 2024 review puts average Andean intake at more than 100 grams a day, far beyond any supplement dose.14

Among 50 adults living at 4,100 meters, the 27 who ate maca regularly had lower levels of the inflammation marker IL-6 and better health-status scores than neighbors who didn't, a pattern that fits maca's old role as a vitality food.21

Maca powder nutrition facts

Quick answer

A tablespoon of maca powder (about 8 grams) has roughly 27 calories, 6 grams of carbohydrate, 0.8 gram of fiber and 1.1 grams of protein, with almost no fat. A 3-gram trial amount is about 10 calories.45

Dried yellow Peruvian maca powder, calculated from lab values per 100 grams of dry matter and adjusted to the powder's 93% dry matter; calories at 4 per gram of protein and nonfiber carbohydrate, 9 per gram of fat, 2 per gram of fiber; zinc from four Peruvian samples.422

Nutrient3 g (a typical trial amount)1 tablespoon (about 8 g)Per 100 g
Calories1027340
Carbohydrate2.2 g6.0 g74.5 g
Fiber (part of carbohydrate)0.3 g0.8 g9.6 g
Protein0.4 g1.1 g13.4 g
Fatunder 0.1 g0.1 g0.8 g
Zincabout 0.1 mg0.2 to 0.3 mg2.5 to 3.6 mg

Use maca as a small addition to a nourishing meal: a spoonful adds little protein or fiber. The powder is mostly starch;19 researchers credit its effects to plant compounds such as macamides and glucosinolates.1419 Read the grams on your label, since a tablespoon runs from 5 to 15 grams by product, and USDA's FoodData Central has no standard entry for maca.5 Minerals vary with the soil.22

What is maca good for?

Quick answer

Maca's best human evidence is for sexual desire, sexual function and menopausal symptom scores, with emerging evidence for mood and energy, all from placebo-controlled trials.2325 Results for male fertility and sports performance are mixed.242930

Where the research stands

Maca has more than 20 human studies; the largest trial started with 193 people, and a multicenter menopause report enrolled 168 women across two trial protocols.192512 Reviews call the evidence limited,231949 and several trials, including the largest menopause series, come from researchers tied to maca sellers.1925

Maca benefits, graded by evidence (updated September 2026). Labels are editorial judgments that compare maca's uses with each other; they aren't formal certainty ratings.
UseEvidenceWhat was studiedWhat the research shows

Sexual desire

Moderate

Gelatinized maca 1.5 to 3 g; powder 3.5 g; extracts

More desire than placebo from week 8 in 57 men and after 14 days in 8 cyclists; red maca extract beat placebo for desire at high altitude, not at low altitude; lower sexual-dysfunction scores in postmenopausal women1646257

Menopause symptom scores

Moderate

Powder or pre-gelatinized maca, 2 to 3.5 g

All four reviewed trials reported better symptom scores, and a 2018 meta-analysis found maca improved sexual function after menopause344

Mood and energy

Emerging

Extract 3 g; powder 3.3 to 3.5 g

Better than placebo at low altitude, not for energy at high altitude; depression scores fell in two trials in women2578

Sexual function on antidepressants

Emerging

Maca root 3 g, 12 weeks

9.5% on maca vs. 4.8% on placebo met one remission cutoff; average scores didn't differ26

Men's sexual-symptom scores

Emerging

Dry extract 2.4 g; gelatinized maca about 5 g

Erectile-function score up 1.6 points vs. 0.5 on placebo, a result a 2018 meta-analysis rated positive but very preliminary; aging-male symptom score down from 45.6 to 35.0, with no gain on placebo275211

Male fertility

Mixed

Maca 2 to 2.8 g, infertile men

One of three trials raised sperm concentration; pooled, no significant gain281024

Sports performance

Mixed

Black maca extract 2.5 g twice a day; maca 2 g

Better shuttle run and strength than placebo in handball players; no change in basketball players2930

How does maca work?

Quick answer

Maca doesn't supply hormones of its own, and in most placebo-controlled trials, sex hormones didn't rise significantly while symptoms eased.7 Of 11 published reports that compared maca with placebo and measured sex hormones, six, in men and women, found no significant rise in any of them.67891011 In a seventh, estradiol, progesterone and prolactin didn't differ from placebo, and changes in testosterone tracked with gains in sexual function in the maca group.26 The other four, all in women around menopause, come from a maca supplier's research group, and two of them report parts of the same multicenter study. In all four, estradiol rose from the body's own production: the researchers described maca as non-hormonal, and in three of the reports FSH fell as estradiol rose.37431240 In the trial in which each woman tried both maca and placebo, cortisol and ACTH also fell.40

  • No hormone-like activity in yeast tests. Maca extracts showed no estrogen- or testosterone-like activity in a yeast-based assay, though one cell study reported estrogen-like activity.742

  • Macamides may act on the nervous system (proposed). These fat-based compounds are the leading candidates for maca's effects on desire, mood and fatigue; an analysis of mostly animal studies credits them with its anti-fatigue effect, and the route hasn't been shown in people.1431

  • Antioxidant activity in cells and animals. A 2024 analysis of lab and animal studies found maca raised antioxidant enzymes; human data are scarce.32

Maca benefits, ranked by evidence

The most encouraging human findings are for sexual desire and menopause symptoms, with emerging evidence for mood, energy and men's sexual symptoms.

1

Sexual desire

Moderate evidenceHuman studyRCTs · 57 men; 14 women

Men on gelatinized maca reported more desire than placebo from week 8, and postmenopausal women on maca powder saw sexual-dysfunction scores fall.167 See maca for women and maca for men.

Study takeaway: desire and sexual function improved on maca.

2

Menopause symptom scores

Moderate evidenceHuman study4 RCTs in a review

All four trials in a 2011 review reported better menopause symptom scores, and in the largest maca menopause report, a standard menopause symptom index in the same 55 women averaged 22 in their placebo month and 10 over the two months on 2 grams a day of maca that followed.312

Study takeaway: four menopause trials all pointed the same way.

3

Mood and energy

Emerging evidenceHuman studyRCT · 193 started, 175 finished

In Peru, 3 grams a day of red or black maca extract improved mood and energy more than placebo in lowlanders over 12 weeks.25 In a 4-week trial of 60 women, fatigue improved in both groups; maca's edge appeared only in women under 45.33

Study takeaway: mood and energy improved at low altitude.

4

Men's sexual-symptom scores

Emerging evidenceHuman study2 RCTs · 50 and 80 men

Men with mild erectile problems gained 1.6 points on a standard erectile-function score versus 0.5 on placebo, and men with aging-male symptoms improved more than on placebo.2711

Study takeaway: symptom and erectile scores improved.

Get the free Perimenopause & Menopause protocol

This free 90-day protocol lays out:

  • Four phases, in order
  • The herbs that work, ranked
  • The foods that carry the transition, plus a 7-day meal plan
  • How to test, ranked

Free with your Dr. Axe account (email or Google). You'll also get the protocol's short email series and the Dr. Axe newsletter; unsubscribe anytime.

Open the free protocol → →

Is maca good for women?

Quick answer

For women, maca's best evidence is for sexual function, menopause symptom scores and mood. In 14 postmenopausal women, 3.5 grams a day of maca powder for six weeks lowered anxiety, depression and sexual-dysfunction scores compared with placebo, while estradiol, FSH, LH and SHBG didn't differ from placebo.7

If hot flashes, night sweats or mood swings brought you here, the trials point one way: a 2011 review found four placebo-controlled menopause trials, and all four reported better symptom scores.3 The largest maca menopause report enrolled 168 women across two trial protocols, and 124 finished. In the 55 women who took placebo for a month and then 2 grams a day of pre-gelatinized maca for two months, a standard menopause symptom index averaged 22 on placebo and 10 on maca, with hot flashes and night sweats easing most, and estradiol rose.12

The same group saw symptoms ease in 18 perimenopausal women, where the researchers counted relief in 74% to 87% of them, with lower blood pressure, body weight and triglycerides,43 and in a trial in which each of 22 early-postmenopausal women tried both maca and placebo; in a separate pilot of nine women in the same report, forearm bone density rose on maca and fell on placebo, a group too small for the authors to test statistically.40 Trials from other teams saw symptoms ease with no significant hormone change. In 29 postmenopausal women, 3.3 grams a day for six weeks lowered depression scores and diastolic blood pressure, with estradiol, FSH and TSH no different from placebo,8 much like the 14-woman trial above.7 A 2018 meta-analysis of plant compounds for sexual function after menopause found maca improved it significantly.44

If an antidepressant has dulled your sex life: in a 12-week trial that analyzed 42 women (21 on 3 grams of maca a day, 21 on placebo), more women on maca reached each of three sexual-function remission cutoffs, from 9.5% versus 4.8% on one scale to 30% versus 20% on another. The gains sat mostly with the 12 postmenopausal women, where 4 of 7 on maca and 1 of 5 on placebo reached that second cutoff, though average scores didn't differ between the groups.26 In an earlier study that compared two doses in 20 people on antidepressants, 17 of them women, 3 grams a day lowered a sexual-dysfunction score from 22.8 to 16.9, while 1.5 grams didn't.47 A 2022 review of supplements for antidepressant-related sexual problems concluded that higher-dose maca may help,48 and a 2026 review placed maca's signal in women with these problems, particularly after menopause.51 Don't stop your antidepressant on your own; tell your prescriber you've added maca.

For perimenopause and menopause, I start by asking why estrogen, progesterone, thyroid hormones or DHEA have dropped, and I'd put someone on a protocol before a pill. Chronic stress is often the first domino, since high cortisol can throw off blood sugar, thyroid and sex hormones, and after menopause the adrenal glands help supply the body's estrogen.34 That protocol covers sleep, steady blood sugar, protein, strength training, support for the stress response, and herbs such as black cohosh, red clover and sage.34

The markers that show where your hormones stand

Bloodwork gives you a baseline; targets need your practitioner's read.

  • FSH and estradiol: These can help clarify where you are in the transition when that's unclear.
  • TSH: Shows how your thyroid is running.
  • Total and free testosterone: If a result comes back unexpectedly high on maca, ask for a retest on a different assay.18
  • Progesterone and DHEA-S: Show whether other hormones your body makes are running low. DHEA-S comes from the adrenal glands, which supply more of the building blocks for sex hormones once the ovaries slow down.
  • Cortisol: Shows how your stress response is running.

See the cellular bloodwork panel

Have results? Analyze them free → →

Does maca work for men?

For men, the best-supported benefit is desire, and it shows up without a significant change in testosterone. In 57 healthy men, 1.5 or 3 grams a day of gelatinized maca raised self-rated desire from week 8, with nothing yet at week 4, and the effect didn't track with mood.162 In 8 trained male cyclists, 14 days of maca extract raised self-rated desire more than placebo.46 The 57-man program found no effect on LH, FSH, prolactin, testosterone or estradiol at either dose,6 and a 2024 review of 27 proposed testosterone boosters, which included two maca studies, didn't list maca among those that raised testosterone.23

Older men show the same pattern. In 88 men over 40 with aging-male symptoms (80 finished), about 5 grams a day of gelatinized maca for 12 weeks lowered a standard aging-male symptom score from 45.6 to 35.0, while the placebo group went from 47.8 to 48.6. The total score on the International Index of Erectile Function, which covers several parts of sexual function, rose 14 points on maca and fell on placebo, urinary symptoms eased, and testosterone didn't differ significantly between the groups.11 So if desire is your goal, maca has trial support (see how to increase libido).

When testosterone runs low, I look first for the root causes: insulin resistance, low vitamin D, low zinc, poor sleep and high cortisol. Then I put the natural work first: eight hours of sleep, strength training, zinc, magnesium, vitamin D and less alcohol. How to increase testosterone covers each step.

If you and your partner are trying to conceive, give maca modest expectations. In an early uncontrolled study, 9 healthy men on 1.5 or 3 grams a day for four months had higher semen volume, sperm count and motility, with no change in reproductive hormones.45 In a placebo-controlled trial of 69 men with mild sperm problems, 2 grams a day for 12 weeks raised sperm concentration more than placebo (15.0 versus 10.2 million per milliliter), with no difference in motility, volume or shape.28 In a placebo-controlled trial of 50 infertile men (39 finished), 2.8 grams a day of gelatinized yellow maca for 16 weeks raised it 40% while placebo raised it 76%, a nonsignificant difference; hormones didn't change except free testosterone, which fell.10

A 2022 review counted a third trial in infertile men that also found no gain in sperm concentration, and pooling two of the trials showed no significant difference.24 These trials measured semen quality, not pregnancy rates, though partners of three men on maca and one on placebo became pregnant during the 16-week trial, too few to show an effect.10 For fertility, I start with blood sugar and insulin: more protein, more fiber, and less sugar and refined carbs.

Red, black or yellow maca?

The colors differ in chemistry, and only a handful of human trials have tested a specific one, so treat color as a preference unless you're matching a study.

ColorChemistryHuman trials of that color

Yellow

Most common in counted harvests4

Gelatinized yellow maca in two semen-quality trials: upward trends in healthy men, not significant; no significant gain over placebo in infertile men910

Red

Extract richer in GABA25

Strongest mood, energy and mountain-sickness results in the 12-week Peruvian trial25

Black

Extract richer in macamides25

Lowered high hemoglobin in highlanders; beat placebo on strength tests in 8 handball players2529

Purple and gray

Least studied19

None identified in a 2024 review19

The fullest review of maca colors lays out the chemistry and notes that color-specific clinical research is still thin.19

Raw vs. gelatinized maca, and how to buy it

Raw (dried) powder

Dried and milled, starch uncooked. Used in the postmenopausal trial.7

Gelatinized powder

Pressure-cooked and dried, which breaks down the starch; researchers describe it as more digestible, though the trials didn't compare how people tolerate the two forms.9 The form in the men's desire trial, two semen-quality trials and the aging-male trial.1691011

Capsules and extracts

Capsules can hold dried powder, gelatinized powder or an extract, so check the form and grams per serving; extract grams aren't interchangeable with powder grams.1125

Gelatinized maca is the closest match to how the Andes has long eaten this root, cooked rather than fresh,14 so it's the traditional alternative if raw powder doesn't sit well with you.

A maca root takes up what's in its soil: in one study, maca grown near Peruvian mines carried cadmium and lead above international food limits,35 and one woman's blood lead rose after she started a maca root powder and fell once she stopped.36 Maca powder diluted with corn, wheat and yam powders has also been reported.19 Buy third-party-tested, single-ingredient powder.

  • Third-party tested for identity and heavy metals, including lead and cadmium

  • Origin named down to the growing region, since maca grown near mining areas can carry more lead and cadmium35

  • Form and color stated, with grams per serving

  • Stored sealed, cool and dry

Want help fitting maca into your routine?

Ask Dr. Axe AI. Answers are grounded in this library, with sources shown.

How much maca should you take a day?

Quick answer

Most human trials used 1.5 to 3.5 grams a day of maca powder or gelatinized powder, often about 3 grams; a few used 4.5 to 5 grams, including gelatinized powder and black maca extract.131129 Trials ran from two weeks to four months, plus one pilot with eight months on maca, and most lasted six to 12 weeks.301237 By weight, 3 grams is roughly a teaspoon, though the trials measured grams and many used capsules or tablets.5

GoalForm in the trialDaily amountHow long

Sexual desire (men)

Gelatinized powder

1.5 to 3 g

12 weeks16

Sexual function, postmenopausal

Dried powder

3.5 g

6 weeks7

Menopause symptom scores

Pre-gelatinized powder

2 g

2 months, after a placebo month12

Mood and energy

Spray-dried extract

3 g

12 weeks25

Aging-male symptoms

Gelatinized powder

About 5 g

12 weeks11

Give maca at least four weeks before you judge it.34 Some trials saw changes within four weeks, but most measured their main results at six weeks to four months, and the desire trial saw no change at week 4.25331612 Start at the low end of the studied range, 1.5 grams a day in the men's desire trial, and take it with food; a step-by-step increase hasn't been tested.16

Maca tastes malty and a little nutty, so it disappears into foods that already have some sweetness.

Blend it into a smoothie with banana and nut butter; see healthy smoothie recipes.
Stir it into oatmeal or yogurt once it's off the heat.
Whisk it into warm milk with cacao and cinnamon.
Choose capsules if you'd rather skip the taste.

Maca vs. ashwagandha

Ashwagandha is best studied for stress and cortisol,38 and for major fatigue with imbalanced cortisol, I consider rhodiola the best herb.

MacaAshwagandha

Best studied for

Desire, sexual function, menopause scores, mood23

Stress, anxiety and cortisol38

Strongest human evidence

Placebo-controlled trials on menopause symptoms and desire316

Meta-analysis of 9 trials in 558 people38

Effect on hormones

See how maca works

Lowered cortisol compared with placebo38

If stress is driving your fatigue, start with cortisol levels and the adaptogenic herbs overview.

What are maca's side effects?

Quick answer

Maca was well tolerated in trials of up to about four months; the largest reported no serious side effects, and a few people had mild stomach upset.2511 The people who should be careful are listed below.

  • Pregnancy or breastfeeding. No human safety studies exist, so skip maca supplements.39

  • A history of breast cancer or another hormone-sensitive cancer. Decide with your oncology team first.39 In a lab study, maca extract made triple-negative breast cancer cells migrate more, at high concentrations tested only in cells.41

  • Thyroid disease. Maca is a crucifer. TSH didn't change significantly in two trials,89 while one reported lower T3.40 Those results don't establish safety with thyroid disease, so stay near trial amounts and have your doctor recheck your thyroid levels after a few months.

  • Lab tests. In one documented case, maca was linked to a falsely high testosterone result on one lab method.18

  • Long-term use. Trials ran two weeks to about four months; one pilot gave eight women maca for eight months.301237

The bottom line

Should you take maca?

Yes, for the right reasons. Maca is a nourishing Andean root, and placebo-controlled trials support it for desire and menopause symptom scores, with promising results for sexual function, mood and energy.

Take 1.5 to 3.5 grams a day of tested powder or gelatinized powder, and give it at least four weeks. If you're pregnant or breastfeeding, have had a hormone-sensitive cancer or have thyroid disease, read who should be careful first. Start with the root cause and the foundations, let this old Andean food support them, and trust that your body was built to heal.

Get the free Perimenopause & Menopause protocol

Four phases, the herbs that work ranked, the foods that carry the transition and a 7-day meal plan. Have recent bloodwork? Analyze it free.

Free with your Dr. Axe account (email or Google). You'll also get the protocol's short email series and the Dr. Axe newsletter; unsubscribe anytime.

Open the free protocol → →

Maca: frequently asked questions

How many calories are in a tablespoon of maca powder?

About 27 calories in an 8-gram tablespoon, with 6 grams of carbohydrate and 1.1 grams of protein.45 Tablespoon weights vary by product, so check the grams on your label.

Does maca increase testosterone?

In placebo-controlled trials, men on maca reported more desire and fewer aging-male symptoms, while testosterone didn't change significantly compared with placebo.16611 For low testosterone, Dr. Axe starts with the root cause and the natural work: sleep, strength training, zinc, magnesium, vitamin D and less alcohol.

Can maca help you get pregnant?

One trial found maca raised sperm concentration: 69 men with mild sperm problems took 2 grams a day for 12 weeks and reached 15.0 versus 10.2 million per milliliter on placebo.28 Across three trials in infertile men, one raised sperm concentration and two didn't, and pregnancy wasn't a trial outcome, though partners of three men on maca and one on placebo conceived during one 16-week trial.1024

How long does maca take to work?

Give it at least four weeks before you judge it.34 One small trial saw more desire after 14 days,46 but most trials measured their main results at six weeks to four months.1612

How much maca should I take a day?

Most trials used 1.5 to 3.5 grams a day of powder or gelatinized powder, often about 3 grams; a few used 4.5 to 5 grams, including gelatinized powder and black maca extract.131129

Should you take maca in the morning or at night?

Trials didn't compare timing, and several split the amount into two or three doses a day.1211 Since people take maca for energy, morning is a sensible start.

Is gelatinized maca better than raw?

Both forms have trial support: gelatinized maca in the men's desire and aging-male trials,1611 and raw powder in a postmenopausal trial.7 Gelatinized maca is cooked to break down its starch, which researchers describe as easier to digest,9 so it's a good pick if raw powder doesn't sit well with you.

Is black maca or red maca better?

In a 12-week trial of extracts, red maca gave stronger mood and energy results, and black maca lowered high hemoglobin in highlanders.25

Does maca help you gain weight?

Not in the trials that tracked it: weight didn't differ from placebo in 80 men, and BMI didn't change in the 12-week Peruvian trial.1125

Is maca safe if you have thyroid disease?

TSH didn't change significantly in two trials.89 If you have thyroid disease, see who should be careful first.

Can you take maca while pregnant or breastfeeding?

Skip maca supplements. No human safety studies exist in pregnancy or breastfeeding.39

Can you take maca with ashwagandha?

The pair hasn't been tested together in a published trial; people take ashwagandha for stress and cortisol, maca for desire and menopause symptoms.3823

Freshness & update log

September 30, 2026 — Rewrote the page in full. Added a nutrition facts table for maca powder (3 grams, 1 tablespoon and 100 grams) from laboratory composition data; rescored under the current herb weighting (editorial score 7.4) with an Interaction check; added the 2023 aging-male trial, 2025 and 2023 athlete trials, a 2022 fatigue trial, a 2026 review, and the full record of human trials that measured sex hormones, including the perimenopause pilot and the 2018 and 2022 reviews of sexual function; corrected the fertility, hormone, blood pressure and color claims from the earlier version; and added guidance on heavy metals, thyroid disease, pregnancy and lab-test interference.

Originally published October 14, 2024. —

References

  1. Beharry S, Heinrich M. Is the hype around the reproductive health claims of maca (Lepidium meyenii Walp.) justified? J Ethnopharmacol. 2018;211:126-170. doi:10.1016/j.jep.2017.08.003. PMID:28811221
  2. Shin BC, Lee MS, Yang EJ, Lim HS, Ernst E. Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complement Altern Med. 2010;10:44. doi:10.1186/1472-6882-10-44. PMID:20691074
  3. Lee MS, Shin BC, Yang EJ, Lim HJ, Ernst E. Maca (Lepidium meyenii) for treatment of menopausal symptoms: A systematic review. Maturitas. 2011;70(3):227-33. doi:10.1016/j.maturitas.2011.07.017. PMID:21840656
  4. Meissner HO, Mscisz A, Piatkowska E, Baraniak M, Mielcarek S, Kedzia B, et al. Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations. Int J Biomed Sci. 2016;12(1):9-24. doi:10.59566/IJBS.2016.12009. PMID:27127450
  5. U.S. Department of Agriculture, Agricultural Research Service. FoodData Central, Branded Foods: single-ingredient maca powder labels (tablespoon weights of 5 to 15 g: FDC IDs 2467006, 2381977, 2410356, 2275036, 2398180; teaspoon weights of 3 to 5 g: FDC IDs 2642714, 2451552, 1868612). Accessed September 26, 2026.
  6. Gonzales GF, Córdova A, Vega K, Chung A, Villena A, Góñez C. Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men. J Endocrinol. 2003;176(1):163-8. doi:10.1677/joe.0.1760163. PMID:12525260
  7. Brooks NA, Wilcox G, Walker KZ, Ashton JF, Cox MB, Stojanovska L. Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content. Menopause. 2008;15(6):1157-62. doi:10.1097/gme.0b013e3181732953. PMID:18784609
  8. Stojanovska L, Law C, Lai B, Chung T, Nelson K, Day S, et al. Maca reduces blood pressure and depression, in a pilot study in postmenopausal women. Climacteric. 2015;18(1):69-78. doi:10.3109/13697137.2014.929649. PMID:24931003
  9. Melnikovova I, Fait T, Kolarova M, Fernandez EC, Milella L. Effect of Lepidium meyenii Walp. on Semen Parameters and Serum Hormone Levels in Healthy Adult Men: A Double-Blind, Randomized, Placebo-Controlled Pilot Study. Evid Based Complement Alternat Med. 2015;2015:324369. doi:10.1155/2015/324369. PMID:26421049
  10. Melnikovova I, Russo D, Fait T, Kolarova M, Tauchen J, Kushniruk N, et al. Evaluation of the effect of Lepidium meyenii Walpers in infertile patients: A randomized, double-blind, placebo-controlled trial. Phytother Res. 2021;35(11):6359-6368. doi:10.1002/ptr.7287. PMID:34585449
  11. Shin D, Jeon SH, Piao J, Park HJ, Tian WJ, Moon DG, et al. Efficacy and Safety of Maca (Lepidium meyenii) in Patients with Symptoms of Late-Onset Hypogonadism: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. World J Mens Health. 2023;41(3):692-700. doi:10.5534/wjmh.220112. PMID:36593713
  12. Meissner HO, Mscisz A, Reich-Bilinska H, Kapczynski W, Mrozikiewicz P, Bobkiewicz-Kozlowska T, et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (II) Physiological and Symptomatic Responses of Early-Postmenopausal Women to Standardized doses of Maca in Double Blind, Randomized, Placebo-Controlled, Multi-Centre Clinical Study. Int J Biomed Sci. 2006;2(4):360-74. PMID:23675005
  13. Bloomer RJ. Effects of Maca (Lepidium Meyenii) on Sexual Health and libido-A Review. J Diet Suppl. 2026;23(5):582-601. doi:10.1080/19390211.2026.2727026. PMID:42680584
  14. Ulloa Del Carpio N, Alvarado-Corella D, Quiñones-Laveriano DM, Araya-Sibaja A, Vega-Baudrit J, Monagas-Juan M, et al. Exploring the chemical and pharmacological variability of Lepidium meyenii: a comprehensive review of the effects of maca. Front Pharmacol. 2024;15:1360422. doi:10.3389/fphar.2024.1360422. PMID:38440178
  15. Gonzales GF, Gonzales C, Gonzales-Castañeda C. Lepidium meyenii (Maca): a plant from the highlands of Peru--from tradition to science. Forsch Komplementmed. 2009;16(6):373-80. doi:10.1159/000264618. PMID:20090350
  16. Gonzales GF, Córdova A, Vega K, Chung A, Villena A, Góñez C, et al. Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia. 2002;34(6):367-72. doi:10.1046/j.1439-0272.2002.00519.x. PMID:12472620
  17. Siwek M, Woroń J, Wrzosek A, Gupało J, Chrobak AA. Harder, better, faster, stronger? Retrospective chart review of adverse events of interactions between adaptogens and antidepressant drugs. Front Pharmacol. 2023;14:1271776. doi:10.3389/fphar.2023.1271776. PMID:37829299
  18. Srikugan L, Sankaralingam A, McGowan B. First case report of testosterone assay-interference in a female taking maca (Lepidium meyenii). BMJ Case Rep. 2011;2011. doi:10.1136/bcr.01.2011.3781. PMID:22700073
  19. Minich DM, Ross K, Frame J, Fahoum M, Warner W, Meissner HO. Not All Maca Is Created Equal: A Review of Colors, Nutrition, Phytochemicals, and Clinical Uses. Nutrients. 2024;16(4). doi:10.3390/nu16040530. PMID:38398854
  20. Valerio LG Jr, Gonzales GF. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol Rev. 2005;24(1):11-35. doi:10.2165/00139709-200524010-00002. PMID:16042502
  21. Gonzales GF, Gasco M, Lozada-Requena I. Role of maca (Lepidium meyenii) consumption on serum interleukin-6 levels and health status in populations living in the Peruvian Central Andes over 4000 m of altitude. Plant Foods Hum Nutr. 2013;68(4):347-51. doi:10.1007/s11130-013-0378-5. PMID:23934543
  22. Zhang J, Wang HM, Zhao YL, Zuo ZT, Wang YZ, Jin H. Comparison of Mineral Element Content in a Functional Food Maca (Lepidium meyenii Walp.) from Asia and South America. J Anal Methods Chem. 2015;2015:530541. doi:10.1155/2015/530541. PMID:26236540
  23. Morgado A, Tsampoukas G, Sokolakis I, Schoentgen N, Urkmez A, Sarikaya S. Do "testosterone boosters" really increase serum total testosterone? A systematic review. Int J Impot Res. 2024;36(4):348-364. doi:10.1038/s41443-023-00763-9. PMID:37697053
  24. Lee HW, Lee MS, Qu F, Lee JW, Kim E. Maca (Lepidium meyenii Walp.) on semen quality parameters: A systematic review and meta-analysis. Front Pharmacol. 2022;13:934740. doi:10.3389/fphar.2022.934740. PMID:36110519
  25. Gonzales-Arimborgo C, Yupanqui I, Montero E, Alarcón-Yaquetto DE, Zevallos-Concha A, Caballero L, et al. Acceptability, Safety, and Efficacy of Oral Administration of Extracts of Black or Red Maca (Lepidium meyenii) in Adult Human Subjects: A Randomized, Double-Blind, Placebo-Controlled Study. Pharmaceuticals (Basel). 2016;9(3). doi:10.3390/ph9030049. PMID:27548190
  26. Dording CM, Schettler PJ, Dalton ED, Parkin SR, Walker RS, Fehling KB, et al. A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evid Based Complement Alternat Med. 2015;2015:949036. doi:10.1155/2015/949036. PMID:25954318
  27. Zenico T, Cicero AF, Valmorri L, Mercuriali M, Bercovich E. Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: a randomised, double-blind clinical trial. Andrologia. 2009;41(2):95-9. doi:10.1111/j.1439-0272.2008.00892.x. PMID:19260845
  28. Alcalde AM, Rabasa J. Does Lepidium meyenii (Maca) improve seminal quality? Andrologia. 2020;52(10):e13755. doi:10.1111/and.13755. PMID:32654242
  29. Kang S, Ahn BO, Park MH, Lim ST, Lee E. Effects of Black Maca supplement on isokinetics muscular performance of elite women's handball players: placebo-controlled, crossover study. Food Nutr Res. 2023;67. doi:10.29219/fnr.v67.10250. PMID:38187794
  30. Wu PS, Wu SH, Jiang RS, Chen CH, Chen BW, Chiu CH. The Impact of Lepidium meyenii (MACA) Supplementation on Basketball-related Performance and Antifatigue Ability: A Double-blind Crossover Study. J Physiol Investig. 2025;68(5):297-304. doi:10.4103/ejpi.EJPI-D-25-00037. PMID:40960048
  31. Huerta Ojeda Á, Rodríguez Rojas J, Cancino-López J, Barahona-Fuentes G, Pavez L, Yeomans-Cabrera MM, et al. Effects of Maca (Lepidium meyenii Walp.) on Physical Performance in Animals and Humans: A Systematic Review and Meta-Analysis. Nutrients. 2024;17(1). doi:10.3390/nu17010107. PMID:39796542
  32. Huerta Ojeda Á, Rodríguez Rojas J, Cuevas Guíñez J, Ciriza Velásquez S, Cancino-López J, Barahona-Fuentes G, et al. The Effects of Maca (Lepidium meyenii Walp) on Cellular Oxidative Stress: A Systematic Review and Meta-Analysis. Antioxidants (Basel). 2024;13(9). doi:10.3390/antiox13091046. PMID:39334705
  33. Honma A, Fujiwara Y, Takei S, Kino T. The improvement of daily fatigue in women following the intake of maca (Lepidium meyenii) extract containing benzyl glucosinolate. Funct Foods Health Dis. 2022;12(4):175. doi:10.31989/ffhd.v12i4.912
  34. Axe J. Perimenopause & Menopause: The 90-Day Healing Protocol. DrAxe.com. 2026.
  35. Orellana Mendoza E, Cuadrado W, Yallico L, Zárate R, Quispe-Melgar HR, Limaymanta CH, et al. Heavy metals in soils and edible tissues of Lepidium meyenii (maca) and health risk assessment in areas influenced by mining activity in the Central region of Peru. Toxicol Rep. 2021;8:1461-1470. doi:10.1016/j.toxrep.2021.07.016. PMID:34401355
  36. Johnson-Arbor K, Vo K, Wong F, Gajek R. Unintentional and Sequential Lead Exposure from a Ceramic Mug and Maca (Lepidium meyenii). J Med Toxicol. 2018;14(2):152-155. doi:10.1007/s13181-017-0649-x. PMID:29313251
  37. Meissner HO, Kapczynski W, Mscisz A, Lutomski J. Use of gelatinized maca (lepidium peruvianum) in early postmenopausal women. Int J Biomed Sci. 2005;1(1):33-45. PMID:23674952
  38. Arumugam V, Vijayakumar V, Balakrishnan A, B Bhandari R, Boopalan D, Ponnurangam R, et al. Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis. Explore (NY). 2024;20(6):103062. doi:10.1016/j.explore.2024.103062. PMID:39348746
  39. Memorial Sloan Kettering Cancer Center. Maca. About Herbs, Botanicals & Other Products. Updated June 7, 2023.
  40. Meissner HO, Mscisz A, Reich-Bilinska H, Mrozikiewicz P, Bobkiewicz-Kozlowska T, Kedzia B, et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (III) Clinical responses of early-postmenopausal women to Maca in double blind, randomized, Placebo-controlled, crossover configuration, outpatient study. Int J Biomed Sci. 2006;2(4):375-94. PMID:23675006
  41. Bizinelli D, Flores Navarro F, Lima Costa Faldoni F. Maca Root (Lepidium meyenii) Extract Increases the Expression of MMP-1 and Stimulates Migration of Triple-Negative Breast Cancer Cells. Nutr Cancer. 2022;74(1):346-356. doi:10.1080/01635581.2021.1882511. PMID:33560149
  42. Valentová K, Buckiová D, Kren V, Peknicová J, Ulrichová J, Simánek V. The in vitro biological activity of Lepidium meyenii extracts. Cell Biol Toxicol. 2006;22(2):91-99. doi:10.1007/s10565-006-0033-0. PMID:16528448
  43. Meissner HO, Reich-Bilinska H, Mscisz A, Kedzia B. Therapeutic Effects of Pre-Gelatinized Maca (Lepidium Peruvianum Chacon) used as a Non-Hormonal Alternative to HRT in Perimenopausal Women - Clinical Pilot Study. Int J Biomed Sci. 2006;2(2):143-59. PMID:23674976
  44. Najaf Najafi M, Ghazanfarpour M. Effect of phytoestrogens on sexual function in menopausal women: a systematic review and meta-analysis. Climacteric. 2018;21(5):437-445. doi:10.1080/13697137.2018.1472566. PMID:30156931
  45. Gonzales GF, Cordova A, Gonzales C, Chung A, Vega K, Villena A. Lepidium meyenii (Maca) improved semen parameters in adult men. Asian J Androl. 2001;3(4):301-3. PMID:11753476
  46. Stone M, Ibarra A, Roller M, Zangara A, Stevenson E. A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen. J Ethnopharmacol. 2009;126(3):574-6. doi:10.1016/j.jep.2009.09.012. PMID:19781622
  47. Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Fava M, et al. A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction. CNS Neurosci Ther. 2008;14(3):182-91. doi:10.1111/j.1755-5949.2008.00052.x. PMID:18801111
  48. Concerto C, Rodolico A, Meo V, Chiappetta D, Bonelli M, Mineo L, et al. A Systematic Review on the Effect of Nutraceuticals on Antidepressant-Induced Sexual Dysfunctions: From Basic Principles to Clinical Applications. Curr Issues Mol Biol. 2022;44(8):3335-3350. doi:10.3390/cimb44080230. PMID:35892716
  49. Ho CY, Hsu CH, Chien TJ. Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials. J Tradit Complement Med. 2026;16(1):109-120. doi:10.1016/j.jtcme.2025.11.001. PMID:41696741
  50. Valentová K, Stejskal D, Bartek J, Dvorácková S, Kren V, Ulrichová J, Simánek V. Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: in vivo safety assessment. Food Chem Toxicol. 2008;46(3):1006-13. doi:10.1016/j.fct.2007.10.031. PMID:18054420
  51. Liu X, Sun Z, Gao J, Fu CY, Yang Z. Plant-derived bioactives in depression-related and antidepressant-associated sexual dysfunction: a narrative review. Front Nutr. 2026;13:1894055. doi:10.3389/fnut.2026.1894055. PMID:42601961
  52. Borrelli F, Colalto C, Delfino DV, Iriti M, Izzo AA. Herbal Dietary Supplements for Erectile Dysfunction: A Systematic Review and Meta-Analysis. Drugs. 2018;78(6):643-673. doi:10.1007/s40265-018-0897-3. PMID:29633089
Dr. Josh Axe, DC, DNM, CNS
Doctor of Natural Medicine · Founder, DrAxe.com

Dr. Axe is a certified doctor of natural medicine, clinical nutritionist, and multiple New York Times bestselling author. He has spent 20+ years in clinical practice helping people heal at the root cause and founded one of the most-visited natural-health platforms in the world.

Read the full bio →

This article is for educational purposes. See our medical disclaimer.