Nutrition

Healthy Seeds: The 10 Healthiest Seeds to Eat, Ranked

The ten healthiest seeds to eat, from ground flaxseed and chia to pumpkin, sesame and pomegranate seeds, ranked on one stated basis, with USDA nutrition per ounce, what the research shows and how to prepare each one.

Meet the Medical Advisory Board
Evidence-based73 sources citedUpdated October 12, 2026
Published Oct 12, 2026Last updated Oct 12, 2026Editorial policyMedical review policyFact-checking policy
Four wooden scoops on burlap holding hulled sesame seeds, brown flaxseeds, dark green pumpkin seeds and hulled sunflower seeds, with more seeds spilled in front
Sesame, flax, pumpkin and sunflower seeds, four of the ten on this list.
Healthy seeds at a glance

The 10 healthiest seeds to eat are flaxseed, chia seeds, black seed, pumpkin seeds, quinoa, sunflower seeds, hemp seeds, sesame seeds, cumin seeds and pomegranate seeds, in that order, ranked first by the human research on eating each seed itself.123

  • Per ounce, hemp seeds lead on protein (9.0 grams) and magnesium (198 milligrams), chia on fiber (9.8 grams) and flaxseed on plant omega-3 (about 6.5 grams)456
  • Flaxseed has pooled trials behind it for blood pressure, blood sugar, cholesterol and weight1789
  • About a handful of nuts and seeds a day, at most, is plenty, and they're best organic, sprouted or dry toasted10
  • Whole seeds and mechanically pressed seed oils belong in your kitchen, while refined seed oils such as canola, soybean and cottonseed oil shouldn't be your everyday fat11

Healthy seeds are some of the most concentrated whole foods you can eat. Each one carries what a new plant needs to get started: fat for energy, protein and a store of minerals. That's why a small handful brings a lot of nutrition with it. An ounce of pumpkin seeds, for example, supplies 168 milligrams of magnesium, 40% of the Daily Value.1213

Seeds were among the first foods given to people in Scripture: "And God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, and every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat" (Genesis 1:29).14

Dr. Josh Axe · Free quiz

Cellular Health Quiz

Loading question one…

They're a regular part of my own diet. On my show, I described my rotation: black sesame during a season when I was focused on what Chinese medicine calls blood building (I'd taken a big tablespoon that morning), plus hemp seeds, flaxseeds and a lot of pumpkin seeds.15 Below are the ten healthiest seeds to eat, ranked, with each seed's numbers per ounce from USDA FoodData Central, how to prepare them, how many to eat and who should be careful.

I think so many people have moved away from nuts and seeds altogether.Dr. Josh Axe, DC, DNM, CNSFrom Cellular Health EXPERT: How to Build Bulletproof Cells for Energy, Detox & Longevity, The Dr. Josh Axe Show (2025), at 10:09
AdvertisementAncient Nutrition Active Peptides
AdvertisementAncient Nutrition Active Peptides

What makes a seed healthy, and how are these ranked?

Quick answer

A healthy seed packs fiber, protein, healthy fats and minerals into a small serving: an ounce of seven of the seeds on this list supplies at least 20% of the Daily Value for five or more nutrients.1365121617418 The ranking puts the seeds with the strongest human research on the seed itself first, then orders each group by how many of my protocols name the seed in their top food lists and how many nutrients an ounce supplies.

The same rule orders every seed. Seeds whose pooled trials show an effect of the seed itself, in the trials of the seed or in the authors' own conclusion, come first: flaxseed, chia and black seed.123 Seeds with at least one randomized trial of the seed eaten as food come next, cumin among them, since its pooled trials mix the powder with extracts.47 Pomegranate seeds, prized for their fiber and their place in Scripture, close the list. Within each group, a seed named in more of my protocols' top food lists ranks higher, and a tie goes to the seed whose ounce supplies more nutrients at 20% of the Daily Value or more, then to the seed that's part of my own seed rotation.191315 That's why quinoa, on three of those lists, comes right after pumpkin seeds, and why sesame, part of my own rotation, comes ahead of cumin.

Every number in this table is for one ounce (28 grams), from USDA FoodData Central.651216174182021

Seed, per ounceCaloriesProtein (g)Fiber (g)Plant omega-3 (g)Magnesium (mg)Nutrients at 20% of the Daily Value or more
Flaxseed1515.27.76.5*1115: fiber, magnesium, copper, manganese, thiamin
Chia seeds1384.79.85.0955: fiber, magnesium, copper, manganese, selenium
Pumpkin seed kernels1588.61.7Under 0.11685: magnesium, phosphorus, zinc, copper, manganese
Sunflower seed kernels1665.92.4Under 0.1927: vitamin E, copper, thiamin, selenium, manganese, vitamin B6, magnesium
Sesame seeds, whole1625.03.30.11005: copper, manganese, magnesium, iron, calcium
Hemp seeds, hulled1579.01.12.51986: manganese, copper, magnesium, phosphorus, thiamin, zinc
Cumin seed1065.03.0Under 0.11045: iron, manganese, copper, magnesium, calcium
Quinoa, uncooked1044.02.0Under 0.1561: manganese
Pomegranate arils240.51.103None

*USDA reports flaxseed's omega-3 as total 18:3 fat, the family that plant omega-3 (ALA) belongs to, and reports sesame, sunflower, cumin and quinoa the same way. Black seed isn't in the table because USDA FoodData Central has no record for it.

If you're looking for seeds high in protein, hemp and pumpkin seeds lead, at 9.0 and 8.6 grams per ounce, and every seed in the table except pomegranate brings at least 4 grams.41220 For more ways to add it, see plant-based protein foods.

Protein per ounce: hemp and pumpkin seeds lead

Protein per ounce: hemp and pumpkin seeds leadEight seeds from this list · per 1-ounce (28-gram) serving · USDA FoodData Central. Hemp seeds, hulled: 9 g protein per ounce; Pumpkin seed kernels: 8.6 g protein per ounce; Sunflower seed kernels: 5.9 g protein per ounce; Flaxseed: 5.2 g protein per ounce; Sesame seeds, whole: 5 g protein per ounce; Cumin seed: 5 g protein per ounce; Chia seeds: 4.7 g protein per ounce; Quinoa, uncooked: 4 g protein per ounceEight seeds from this list · per 1-ounce (28-gram) serving ·USDA FoodData CentralHemp seeds,hulled9 g protein per ouncePumpkin seedkernels8.6 g protein per ounceSunflower seedkernels5.9 g protein per ounceFlaxseed5.2 g protein per ounceSesame seeds,whole5 g protein per ounceCumin seed5 g protein per ounceChia seeds4.7 g protein per ounceQuinoa, uncooked4 g protein per ounce
Source: USDA FoodData Central, SR Legacy records for each seed (chia and quinoa: references 5 and 20) [4, 12, 16, 6, 17, 18]Pomegranate arils carry 0.5 grams of protein per ounce, and USDA has no record for black seed.

Get the free Anti-Inflammatory Reset

Walnuts and flax are on its list of top foods for cooling inflammation, and fried food and seed oils are on its list to cut. Inside this free protocol:

  • The four-phase, 30-day plan to cool chronic inflammation
  • The foods that cool inflammation, plus a 7-day meal plan
  • How to test for inflammation, ranked

Free with your Dr. Axe account (email or Google). You'll also get the protocol's short email series and the Dr. Axe newsletter; unsubscribe anytime.

Open the free protocol →

The 10 healthiest seeds to eat, ranked

These are the best seeds to eat for your health, in order. Each card gives the seed's numbers per ounce, the strongest human research behind it, with the form each trial used, where it fits in my own recommendations and how to eat it. The badge on each card rates the research behind that card.

1

Flaxseed

Strong evidenceHuman studyMeta-analyses of 15 to 62 trials · placebo-controlled trial of 110 adults

An ounce of flaxseed carries 151 calories, 7.7 grams of fiber (28% of the Daily Value), 111 milligrams of magnesium and about 6.5 grams of plant omega-3, plus more than a third of your day's thiamin and copper.613 Two tablespoons of ground flax, about 14 grams, give you 75 calories, 3.8 grams of fiber and 55 milligrams of magnesium.6

In a placebo-controlled trial of 110 people with peripheral artery disease, foods made with 30 grams of milled flaxseed a day for 6 months left systolic blood pressure about 10 points lower and diastolic about 7 points lower than placebo. In the people who started with systolic pressure of 140 or higher, systolic fell 15 points. Neither the people nor the researchers knew who got what.22 Across 15 controlled trials with 1,302 people, flaxseed in its various forms lowered systolic pressure by 2.85 points and diastolic by 2.39, and the trials that used flaxseed powder lowered them by 1.81 and 1.28.1

The seed helps with blood sugar and weight too. Across 25 placebo-controlled trials, flaxseed lowered fasting blood sugar by 2.94 mg/dL along with insulin and insulin resistance, and those gains came from the seed itself rather than flax oil or lignan extracts; HbA1c didn't change.7 Across 45 placebo-controlled trials, flaxseed trimmed weight by 0.99 kilograms and waist size by 0.8 centimeters on average, with the clearest results in trials of whole flaxseed at 30 grams a day or more, in trials of 12 weeks or longer and in people with a BMI of 27 or higher.9

Across 62 randomized trials with 3,772 people, which tested flaxseed in several forms, it lowered total cholesterol by 5.39 mg/dL, LDL by 4.21 and triglycerides by 9.42, with no change in HDL.8

For reducing inflammation, walnuts and ground flaxseed are generally the best nuts and seeds you can eat, and they share a slot on the top 10 foods list of my Anti-Inflammatory Reset, one of seven protocols whose top food lists include flax.232419 My Hormone Balance for Women protocol calls for 2 tablespoons of ground flax a day, and my Type 2 Diabetes Protocol lists flax and chia among its top blood-sugar foods.2526 Stir ground flax into a smoothie, oatmeal or goat milk yogurt, or bake with it; the section on preparing seeds below explains why grinding matters.

2

Chia seeds

Strong evidenceHuman studyTwo meta-analyses of 8 trials each · randomized trial of 24 women

An ounce of chia seeds carries 138 calories, 9.8 grams of fiber, the most per ounce on this list, and 5.0 grams of plant omega-3, plus selenium, manganese, copper and magnesium at 20% of the Daily Value or more.513

Chia's clearest result is on blood pressure. A 2025 analysis of 8 randomized trials found systolic pressure 7.19 points lower and diastolic 6.04 lower with chia seed, and a second 2025 analysis of 8 trials with 372 people found drops of 5.61 and 7.49, along with a waist 1.46 centimeters smaller.227 The analysis with the 7.19-point drop found no change in weight or fasting blood sugar.2

Chia also helps you feel full. In a randomized trial in which 24 young women each tried three mid-morning snacks on separate days, plain yogurt or yogurt with 7 or 14 grams of chia stirred in, they ate about 1,096 calories at lunch after the plain yogurt and about 818 after the 7-gram chia yogurt, about 25% less.28

Chia is on my Type 2 Diabetes Protocol's top 10 list alongside flax, and it's on my food list of nuts and seeds.2610 Soak it before you eat it: in liquid it swells into a soft gel,29 the base of a chia seed pudding you can make with full-fat coconut milk and a teaspoon of raw honey. For more ideas, see how to eat chia seeds.

3

Black seed (nigella)

Strong evidenceHuman studyMeta-analysis of 11 trials, 860 people · placebo-controlled trial of 47 adults

Black seed, also called nigella or black cumin, has a long history of use across the Middle East and parts of India, and it has been tested in 82 randomized trials with 5,026 people.1130

Across 11 randomized trials with 860 people, which used ground seed powder or oil for about 8 weeks, blood pressure in the black seed groups fell from about 133/83 to 125/78 mmHg, 3.26 and 2.80 points more than in the comparison groups.3 The ground seed itself was tested in Hashimoto's thyroiditis: in a placebo-controlled trial of 47 adults, 40 of whom finished, 2 grams of ground black seed a day for 8 weeks cut anti-TPO antibodies, the immune markers that attack the thyroid, by half, from about 295 to 148 IU/mL, while the placebo group barely moved, from about 278 to 274.31

In a year-long trial of 114 adults with type 2 diabetes who kept taking their usual medicines, assigned by convenience rather than by chance, 2 grams of black seed a day lowered fasting blood sugar from 195 to 172 mg/dL and HbA1c from 8.6% to 8.2%, while the placebo group held at 180 mg/dL and rose from 8.2% to 8.5%.32

Of the pressed seed oils, I've said black seed oil may be the most powerful of them all.11 As a food, a pinch of the seeds goes a long way: toast them briefly in a dry pan and sprinkle them over vegetables, eggs or flatbread. For supplement amounts and medicine notes, see the black seed oil guide.

4

Pumpkin seeds

Moderate evidenceHuman studyRandomized trial of 1,431 men · 12 months

An ounce of pumpkin seed kernels, also called pepitas, carries 158 calories, 8.6 grams of protein and 168 milligrams of magnesium, 40% of the Daily Value, plus 2.2 milligrams of zinc (20%) and more than half your day's manganese.1213 They're one of the richest food sources of magnesium, and they make the top food lists of 11 of my protocols, more than any other seed, from deep sleep and perimenopause and menopause to a candida cleanse, often at about ¼ cup, for their magnesium and zinc.19333435

In a 12-month trial of 1,431 men aged 50 to 80 with an enlarged prostate, 58.5% of the men who ate 5 grams of pumpkin seeds twice a day improved by at least 5 points on a standard urinary symptom score, against 47.3% on placebo. The authors called that a clinically relevant drop in symptoms; the men eating the seeds knew what they were eating, and the authors reported the difference descriptively.36

If your goal is to support testosterone, balance hormones and boost immunity, I've said pumpkin seeds may be the winner among nuts and seeds, and they're high in zinc, which is critical for testosterone production.2337 For men, one thing I sometimes suggest is a tablespoon of sprouted pumpkin seed butter in a morning smoothie.37 Eat the kernels raw or dry toasted, by the handful or over salads.

5

Quinoa

Moderate evidenceHuman studyRandomized trial of 207 adults · 1 year

Quinoa is a seed you cook like a grain, and it provides all nine essential amino acids, alongside polyphenols like quercetin.38 An ounce of uncooked quinoa carries 104 calories, 4.0 grams of protein, 2.0 grams of fiber and a quarter of your day's manganese.2013

In a year-long randomized trial of 207 adults in China with impaired glucose tolerance, the stage before diabetes, swapping 100 grams of quinoa a day for about half of their usual staple food kept blood sugar in the healthy range for longer, returned more people to normal glucose tolerance, and lowered after-meal blood sugar, insulin resistance and new cases of diabetes, compared with both a mixed whole-grain group and a control group.39 In another trial, 40 adults aged 50 to 75 each ate 15 grams a day of biscuits made mostly with quinoa flour for 4 weeks and wheat biscuits for another 4, in random order, and neither they nor the researchers knew which biscuit was which. On quinoa, total cholesterol fell 0.30 mmol/L (about 12 mg/dL) and LDL 0.25 mmol/L (about 10 mg/dL) more, and weight dipped 0.61 kilograms.40

Quinoa is on the top food lists of three of my protocols, the Acid Reflux & GERD Protocol, the Breast Cancer Support Protocol and the Integrative Cancer Support Guide, as an easy-to-digest grain and a source of fiber.414243 Use it in place of white rice or pasta, in grain bowls, or cooked and chilled in a salad with pumpkin seeds.

6

Sunflower seeds

Emerging evidenceHuman studyFeeding study of 22 women · each tried both diets

An ounce of sunflower seed kernels carries 166 calories and 10.0 milligrams of vitamin E, 67% of the Daily Value, plus copper, thiamin, selenium, manganese, vitamin B6 and magnesium at 20% or more: seven nutrients at that level, the most of any seed on this list.1613

In a feeding study in New Zealand, 22 postmenopausal women with type 2 diabetes ate a fully supplied diet with 30 grams of sunflower kernels a day for 3 weeks, and for another 3 weeks the same diet with 30 grams of almonds instead, in random order. On sunflower kernels, total cholesterol fell from 6.11 to 5.56 mmol/L (about 236 to 215 mg/dL), LDL by 9.5%, triglycerides by 12% and fasting blood sugar by 11%. Almonds did about as well on most measures, while HDL dipped about 3 mg/dL on sunflower kernels and held steady on almonds.44

Sunflower seeds are on my food list of nuts and seeds, and they're one of the four seeds in seed cycling, covered below.1025 Choose shelled kernels, raw or dry toasted, or spread sunflower seed butter on apple slices.

7

Hemp seeds

Emerging evidenceHuman studyRandomized trial of 30 adults · each tried both

Hulled hemp seeds, often sold as hemp hearts, carry the most protein and magnesium per ounce on this list: 9.0 grams of protein and 198 milligrams of magnesium, 47% of the Daily Value, plus 94% of your day's manganese and 2.5 grams of plant omega-3.413 Three tablespoons, 30 grams, bring 9.5 grams of protein.4

In a 4-week trial, 30 adults with a BMI of 25 to 35 ate 60 grams of hulled hemp seeds a day plus 30 grams of hemp oil, and for another 4 weeks hulled sesame seeds and soybean oil instead. Each person tried both in random order, and neither the people nor the researchers knew which seeds they got. After the hemp period, plant omega-3 (ALA) and EPA were higher in their red blood cells, and cholesterol, blood sugar and blood pressure came out about the same as on the sesame-and-soybean-oil period it was compared with.45

Hemp seeds and hemp seed butter are on my food list, and hemp is part of my own rotation.1015 Hemp's fat is heat-fragile, so add the seeds after cooking: over salads, in smoothies or on goat milk yogurt.11

8

Sesame seeds

Emerging evidenceHuman studyRandomized trials of 24 to 41 adults

An ounce of whole sesame seeds carries 162 calories, 276 milligrams of calcium (21% of the Daily Value), 4.1 milligrams of iron (23%) and more than a full day's copper (129%).1713 Most of that calcium sits in the hull: an ounce of hulled sesame kernels carries 17 milligrams, and an ounce of tahini made from roasted kernels carries 121.4849 For calcium, choose whole, unhulled seeds.

Sesame has been tested in several randomized trials. In a placebo-controlled trial of 26 postmenopausal women, 24 of whom finished, 50 grams of sesame seed powder a day for 5 weeks lowered total cholesterol by 5% and LDL by 10%, and both changes differed from the rice-powder placebo period; each woman tried both, with a 3-week break between.50 In a randomized trial of 41 adults with type 2 diabetes, 2 tablespoons (about 28 grams) a day of ardeh, a paste of ground unhulled sesame, in place of part of breakfast for 6 weeks lowered triglycerides by 15.3 mg/dL in the sesame group.51

Black sesame, part of the rotation I described above, has its own trial. In a placebo-controlled trial of 30 adults with prehypertension, 15 in each group, 2.52 grams a day of black sesame meal in capsules, the ground seed left after roasted black sesame is pressed for its oil, lowered systolic pressure from 129.3 to 121.0 in 4 weeks, a larger drop than in the placebo group, which went from 130.4 to 130.6. Diastolic pressure didn't differ between the groups.52 Sprinkle whole seeds over vegetables and stir-fries, and use tahini in dressings and hummus; tahini and sesame butter are on my food list too.10

Black sesame meal lowered systolic pressure from 129.3 to 121.0 in 4 weeks

Black sesame meal lowered systolic pressure from 129.3 to 121.0 in 4 weeks30 adults with prehypertension, 15 in each group · 2.52 grams of black sesame meal a day in capsules · 4 weeks · black sesame group. Before: 129.3 mmHg systolic; After 4 weeks: 121 mmHg systolic30 adults with prehypertension, 15 in each group · 2.52grams of black sesame meal a day in capsules · 4 weeks ·black sesame group
129.3 mmHg systolic
BEFORE
121 mmHg systolic
AFTER 4 WEEKS
-8.3 mmHg systolic · -6.4%
Source: Wichitsranoi et al. · Nutrition Journal, 2011 [52]In the placebo group, systolic pressure was 130.4 before and 130.6 after.
9

Cumin seeds

Emerging evidenceHuman studyRandomized trial of 88 women · meta-analysis of 6 trials

Cumin is one of the spices of Scripture: "doth he not cast abroad the fitches, and scatter the cummin" (Isaiah 28:25).14 It's named in three verses of the Bible, and it has a long traditional use for digestive and respiratory complaints.10

Per ounce, cumin seed carries 18.8 milligrams of iron, more than a full day's worth (105%), but you'll eat it by the teaspoon: a teaspoon of whole seed, 2.1 grams, brings 1.39 milligrams of iron, 8% of the Daily Value.1813

In a randomized trial of 88 overweight or obese women on a weight-loss diet, 3 grams of cumin powder a day, stirred into yogurt at two meals for 3 months, lowered weight, BMI, waist size and body fat, along with total cholesterol, triglycerides and LDL, and raised HDL, compared with yogurt alone; fasting blood sugar didn't change.46 Across 6 randomized trials with 376 people, cumin powder or extract lowered total cholesterol by 10.90 mg/dL and LDL by 6.94, and raised HDL by 3.35.47 Use cumin whole or ground in chili, soups and stews.10

10

Pomegranate seeds

Emerging evidenceHuman studyMeta-analysis · 8 placebo-controlled trials of the juice

Pomegranate seeds, the jewel-red arils inside the fruit, are each a small seed wrapped in a sac of juice, and half a cup of them carries 72 calories and 3.5 grams of fiber.21 Pomegranates grew in the Promised Land, "a land of wheat, and barley, and vines, and fig trees, and pomegranates; a land of oil olive, and honey" (Deuteronomy 8:8), and they're number 2 on my list of the top 10 Bible foods that heal.1453

The human trials so far have tested the juice: across 8 placebo-controlled trials, pomegranate juice lowered systolic blood pressure by about 5 points (4.96 mmHg) and diastolic pressure by about 2.54

About ½ to 1 cup of arils a day is a sensible amount, and pomegranate is on the top food lists of six of my protocols; my Perimenopause & Menopause protocol pairs it with berries.551934 Stir the arils into goat milk kefir or yogurt, or scatter them over a salad.

What's the difference between whole seeds and seed oils?

Quick answer

Whole seeds bring their fiber, minerals and antioxidants with them, while refined seed oils such as canola, soybean, cottonseed and safflower oil are extracted with hexane, bleached and deodorized, and they shouldn't be your everyday fat.11 Oils mechanically pressed from flax, sesame and pumpkin seeds keep their antioxidants and belong in a separate group.11

On my show, I've put the refined oils in one group: soybean, canola, cottonseed, sunflower, safflower, grapeseed and rice bran oil. They're very high in omega-6 fats, which can drive inflammation when they aren't balanced with omega-3s, and they're the oils reheated again and again in restaurant deep fryers.11

The oils pressed from seeds work differently. Flaxseed oil, sesame oil and pumpkin seed oil are mechanically pressed, the way olive oil is, with no solvents, and their antioxidants stay intact.11 Flax, chia and hemp oils are rich in plant omega-3 but heat-fragile, so use them in smoothies, drizzles and dressings, and keep sesame oil to low and medium heat.11 For everyday cooking, put your focus on extra virgin olive oil, avocado oil and coconut oil, then ghee.11

You don't want to go overboard with oils either. You want to get most of your fat from actual food.Dr. Josh Axe, DC, DNM, CNSFrom You Were Lied To About Seed Oils! The Truth About Butter, Tallow & Olive Oil, The Dr. Josh Axe Show (2026), at 29:23

Whole seeds are that kind of food. Linoleic acid, the main omega-6 fat in sunflower, pumpkin, sesame and hemp seeds, is fine to eat in a whole seed, where it comes packaged with fiber, minerals and vitamin E. The concern is the industrially refined oil stripped out of the seed.56 Per ounce, hemp seeds carry 7.8 grams of linoleic acid alongside their 2.5 grams of plant omega-3, and sunflower kernels carry 6.5 grams.416 Eating more omega-3 alongside them keeps the balance, which the next section covers. For the full picture, see seed oils.

Do seeds give you omega-3s?

Quick answer

Yes: an ounce of flaxseed carries about 6.5 grams of plant omega-3 fat, chia 5.0 grams and hemp seeds 2.5 grams, as ALA (alpha-linolenic acid).654 Your body converts only a limited share of ALA into EPA and DHA, the omega-3s in fish, so wild-caught fish fills that gap.5758

Plant omega-3 has its own benefits. Across 41 studies that followed about 1.2 million people over time, those who ate the most ALA had a 10% lower risk of death from any cause and an 8% lower risk of death from cardiovascular disease than those who ate the least, and each extra gram a day was linked to a 5% lower risk of both; deaths from cancer ran slightly higher, by 6%.59 An ounce of chia supplies 5 grams.5

Genetic testing showed that I don't convert ALA well to DHA and EPA, so I eat a lot of wild-caught salmon and other wild fish, and I still eat walnuts, flax and chia, which have benefits of their own.58 For EPA and DHA, choose wild-caught fish with fins and scales, such as salmon and sardines, and let seeds supply ALA alongside them.58 For more sources, see omega-3 foods.

How should you prepare seeds?

Quick answer

Grind flaxseed, soak chia, and choose seeds that are organic, sprouted or dry toasted, skipping seeds roasted in oil or honey-roasted.1060 Sprouting and fermenting also lower phytic acid, which makes the minerals in seeds easier to absorb.38

On my food list in The Biblio Diet, nuts, seeds and their butters are best organic, sprouted or dry toasted, and nuts or seeds roasted in oil, along with honey-roasted nuts, are on the avoid side.10

Grind flaxseed. In a trial of 12 healthy adults who each ate whole, crushed and ground flaxseed for 10 days at a time, about 0.3 grams per kilogram of body weight a day, whole seeds delivered 28% and crushed seeds 43% of the enterolignans, the forms of flax lignans your body absorbs, that ground seeds put into the blood, with ground seed set at 100%.60 In a 3-month trial in healthy adults, milled flaxseed baked into muffins raised ALA in the blood within a month, while whole seed didn't, and no one dropped out of the milled-seed group.61

Ground flaxseed put more than three times as many lignans into the blood as whole seed

Ground flaxseed put more than three times as many lignans into the blood as whole seed12 healthy adults · each tried whole, crushed and ground flaxseed for 10 days · blood enterolignans, relative to ground flaxseed. Ground flaxseed: 100 % of ground flaxseed; Crushed flaxseed: 43 % of ground flaxseed; Whole flaxseed: 28 % of ground flaxseed12 healthy adults · each tried whole, crushed and groundflaxseed for 10 days · blood enterolignans, relative toground flaxseedGround flaxseed100 % of ground flaxseedCrushed flaxseed43 % of ground flaxseedWhole flaxseed28 % of ground flaxseed
Source: Kuijsten et al. · Journal of Nutrition, 2005 [60]Ground flaxseed is set at 100%; whole seeds delivered 28% and crushed seeds 43% of that.

Soak chia. Stir chia into water, milk or another liquid and let it gel before you eat it; the safety section below explains why.

Soak, sprout or ferment. Seeds store much of their phosphorus as phytic acid, one of the antinutrients, which binds minerals such as zinc and iron in the gut.62 In one model, adding 1,000 milligrams of phytate to the diet doubled the estimated zinc requirement.63 Sprouting and fermenting lower phytic acid and make more iron, zinc, calcium and magnesium available, and soaking nuts and seeds, then drying them in a low-temperature oven or a dehydrator, makes them easier to digest.3810 Sprouted seeds and sprouted seed butters have that work done for you; see sprouts for more.

Dry toast. Toast seeds in a dry skillet over medium heat for a few minutes, stirring, until they smell nutty, and let them cool before you store them.

What is seed cycling?

Quick answer

Seed cycling pairs certain seeds with the two halves of the menstrual cycle: a tablespoon each of ground flax and pumpkin seeds a day on days 1 to 14, then a tablespoon each of sunflower and sesame seeds on days 15 to 28.25

Seed cycling is part of Phase 3 of my Hormone Balance for Women protocol.25 Sesame carries lignans much like flax's, which is why both are on my list of foods that support women's hormones.37

The number one food for supporting estrogen in the body is flaxseed or flax meal. It's really high in lignans, which have a phytoestrogen effect on the body.Dr. Josh Axe, DC, DNM, CNSFrom Women NEED to Know This Before Getting on HRT, The Dr. Josh Axe Show (2026), at 30:40

Here's how the lignans in flax and sesame reach your body:

1Seeds bring plant lignans

Flaxseed is one of the richest sources of plant lignans, and in a randomized trial in which healthy postmenopausal women each ate flaxseed, sesame and combined seed bars for 4 weeks at a time, whole sesame seeds produced as much lignan in the body as whole flaxseed.6064

2Gut bacteria convert them

Bacteria in your colon turn plant lignans into enterodiol and enterolactone, the forms your body absorbs.6064

3Grinding lets more through

Ground flaxseed put more of those compounds into the blood than crushed or whole seed.60

4They reach your blood

In the placebo-controlled trial of 110 people with peripheral artery disease, blood levels of enterolignans and plant omega-3 rose 2 to 50 times over with 30 grams of milled flaxseed a day for 6 months.22

5Estrogen breakdown shifts

In 28 postmenopausal women who each tried 0, 5 and 10 grams of ground flaxseed a day for 7 weeks at a time, flax shifted more estrogen toward the 2-hydroxy breakdown pathway, and more so at the higher amount.65

Seed cycling has started to be studied as a whole. In a 2025 review of 10 small studies with 635 women with PMS or polycystic ovary syndrome (PCOS), seed cycling, or the seeds in it, especially flax and sesame, was linked with more regular cycles, milder PMS symptoms and better metabolic markers.66 The full 90-day plan, with the seed-cycling phase and meals, is in my Hormone Balance for Women protocol, and my PCOS protocol names pumpkin seeds and flax among its top foods.2519

How many seeds should you eat a day?

Quick answer

Keep nuts and seeds to about a handful a day at most. While they're a great source of fats, energy and nutrition, they can be hard on the gut.10

My protocols use specific amounts inside that handful: 2 tablespoons of ground flax a day, about ¼ cup of pumpkin seeds, or a tablespoon each of two seeds for seed cycling.2533 An ounce of flax, chia, pumpkin, sunflower, sesame or hemp seeds carries 138 to 166 calories.516 The trials above used larger amounts for weeks to months, such as 30 grams of milled flaxseed, 50 grams of sesame powder or 60 grams of hulled hemp seeds a day.225045

Building seeds into your week?

Ask Dr. Axe AI. Its answers draw on this library and show their sources.

What other seeds can you eat?

Plenty of other edible seeds belong in a healthy kitchen. These types of seeds to eat are worth knowing too:

  • Poppy seeds: An ounce of poppy seeds carries 408 milligrams of calcium, 31% of the Daily Value, and 83% of your day's manganese.6713
  • Pine nuts: Pine nuts are the seeds of pine trees, and an ounce carries more than a full day's manganese (108%).6813
  • Watermelon seeds: An ounce of dried watermelon seed kernels carries 8.0 grams of protein and 146 milligrams of magnesium.69
  • Spice seeds: Caraway seeds, celery seed, anise seed, fennel and fenugreek season food by the teaspoon.

If you're weighing seeds against nuts, see the healthiest nuts, and for a side-by-side of the two most popular omega-3 seeds, see chia seeds vs. flax seeds.

Who should be careful with seeds?

Quick answer

Seeds are everyday foods for most people. The cautions are a seed allergy, especially to sesame or sunflower; chia eaten dry; kidney disease with a phosphorus limit; blood pressure or blood sugar medicines; and poppy seeds before a drug test.70712943272

Take extra care with seeds if any of these apply:
  • Sesame or another seed allergy: Sesame became the ninth major food allergen in the U.S. under the FASTER Act, and packaged foods must label it as of January 1, 2023.70 Sunflower seed allergy is uncommon but can be serious: at a New York pediatric center, 10 of 72 supervised sunflower seed challenges brought a reaction, and 4 of those were treated with epinephrine.71 If you've reacted to a seed, avoid it, its butter and its oil, and work with your allergist.

  • Chia eaten dry: Soak chia first. In a 2017 case report, a man with a long history of trouble swallowing swallowed a tablespoon of dry chia seeds followed by a glass of water, and the seeds swelled into a gel that blocked his esophagus until doctors cleared it.29

  • New to fiber: Add high-fiber seeds gradually, with plenty of water. In a 3-month flax trial, people in every group had some stomach discomfort in the first weeks, and it faded in the milled-seed group.61

  • Kidney disease: An ounce of hemp seeds carries 468 milligrams of phosphorus and an ounce of pumpkin seeds 349, so with kidney disease or a phosphorus limit, count them against the limit your care team has set.412

  • Blood pressure and blood sugar medicines: Flax, chia, black seed and sesame lowered blood pressure or blood sugar in the trials above, and black seed lowered blood sugar in people already taking diabetes medicines.32 If you take medicine for either, keep checking your numbers as you add these seeds, and tell the doctor who manages your prescription. Read the black seed oil guide before taking black seed in supplement amounts.

  • Poppy seeds and drug tests: When 10 healthy adults ate 100 grams of poppy seed paste at breakfast, their urine tested positive for opiates for up to 48 hours at a 300 ng/mL screening cutoff and up to 12 hours at 2,000 ng/mL. Skip poppy seeds for a few days before a drug test.72

The bottom line

Why eat healthy seeds every day?

Seeds are one of the simplest ways to add fiber, protein, healthy fats and minerals to your day, and a handful goes a long way. Flaxseed leads this list, chia and black seed follow with pooled trials of their own, and pumpkin seeds, quinoa, sunflower, hemp, sesame, cumin and pomegranate seeds each bring their own strengths, from magnesium and vitamin E to calcium, iron and fiber.

Seeds have been valued for a very long time, from Genesis to the kitchens of the Middle East and India, and modern trials now line up with that tradition on blood pressure for flax, chia, black seed and sesame, on blood sugar for flax and quinoa, and on prostate symptoms for pumpkin seeds.

Start this week: stir 2 tablespoons of ground flax into your morning smoothie, keep pumpkin seeds within reach for a snack, and soak a spoonful of chia overnight. Choose seeds that are organic, sprouted or dry toasted, and leave refined seed oils out of your cooking. The Omega-3 Index and hs-CRP are two markers that show how your fats and inflammation are trending. Analyze your bloodwork free →

Your body was designed to heal, and whole foods like these give it the raw materials to do that work.

Healthy seeds: frequently asked questions

What is the healthiest seed to eat?

Flaxseed tops this list. Pooled trials show benefits of the seed itself for blood pressure, blood sugar and weight, and it's on more of my protocols' top food lists than chia or black seed, which come next.179252426

Are seeds good for you?

Yes. An ounce of seven of the seeds on this list supplies at least 20% of the Daily Value for five or more nutrients, and flax, chia, black seed and sesame have each lowered blood pressure in human trials.1312352

Which seeds are highest in protein?

Hemp seeds, at 9.0 grams per ounce, followed by pumpkin seeds at 8.6 and sunflower seeds at 5.9.41216 Three tablespoons of hemp hearts bring 9.5 grams.4

Which seeds have the most omega-3?

Flaxseed, with about 6.5 grams of plant omega-3 per ounce, then chia at 5.0 grams and hemp seeds at 2.5.654 For EPA and DHA, eat wild-caught fish alongside them.58

Which seeds are best for weight loss?

Flaxseed has the clearest record. Across 45 placebo-controlled trials, it trimmed weight by 0.99 kilograms and waist size by 0.8 centimeters on average, with the clearest results in trials of whole flaxseed at 30 grams a day or more and in trials of 12 weeks or longer.9 Chia helps with fullness: in a randomized trial of 24 young women, they ate about 25% less at lunch after a chia yogurt snack.28

How many seeds should you eat a day?

About a handful of nuts and seeds a day, at most.10 Within that, my protocols use 2 tablespoons of ground flax, about ¼ cup of pumpkin seeds, or a tablespoon each of two seeds for seed cycling.2533

Should seeds be raw or roasted?

Either raw or dry toasted works; the ones to skip are seeds roasted in oil or honey-roasted. Organic, sprouted or dry toasted seeds are best.10 You can dry toast your own in a skillet in a few minutes.

Do you need to soak seeds?

Soak chia every time.29 Soaking other seeds and then drying them at low heat makes them easier to digest, and sprouting goes further by lowering phytic acid.1038

Are chia seeds or flaxseeds better?

Both earn a place in your week. Chia has more fiber per ounce (9.8 grams against 7.7) and flax more plant omega-3 (about 6.5 grams against 5.0), and both lowered blood pressure in pooled trials.5621 Grind flax and soak chia.

Are poppy seeds healthy?

Yes, in food amounts: an ounce carries 408 milligrams of calcium, 31% of the Daily Value.6713 If you have a drug test coming up, see the poppy seed note in the safety section.

Can you eat seeds if you've had diverticulitis?

Yes. The American College of Gastroenterology's 2026 guideline says people with a history of diverticulitis shouldn't avoid nuts, corn, seeds or popcorn to prevent it from coming back.73

Which seeds are good for women's hormones?

Flaxseed comes first, and seed cycling adds pumpkin, sunflower and sesame seeds through the month: flax and pumpkin on days 1 to 14, sunflower and sesame on days 15 to 28.3725

Are pumpkin seeds good for men?

Yes. They're high in zinc, which is critical for testosterone production, and in a 12-month randomized trial of 1,431 men with an enlarged prostate, 58.5% of the men eating pumpkin seeds, who knew what they were eating, improved on a urinary symptom score, against 47.3% on placebo.3736

Freshness & method note

October 12, 2026 — Rebuilt the page to the current DrAxe.com standard. The ten seeds are now ranked on one stated basis, the human research on each seed itself first, with per-ounce nutrition from USDA FoodData Central for every seed in place of the earlier mix of serving sizes. Black seed and cumin joined the list, and poppy seeds and pine nuts moved to a new section on other edible seeds. Added the trials behind each seed with 73 numbered references, three charts, a diagram of how flax and sesame lignans reach the body, and new sections on seed oils, omega-3s, preparing seeds, seed cycling, daily amounts and safety, including sesame allergen labeling and poppy seeds and drug tests. Corrected the sunflower serving (the earlier "one cup (about 46 grams)" was USDA's kernel yield from a cup of seeds in the shell) and retired benefit claims that weren't tied to a source.

References

  1. Ursoniu S, Sahebkar A, Andrica F, Serban C, Banach M. Effects of flaxseed supplements on blood pressure: A systematic review and meta-analysis of controlled clinical trial. Clin Nutr. 2016;35(3):615-25. doi:10.1016/j.clnu.2015.05.012. PMID:26071633
  2. TaghipourSheshdeh F, Behzadi M, Bashiri S, Mohammadi-Sartang M. The Effect of Chia Seed on Blood Pressure, Body Composition, and Glycemic Control: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials. Nutr Rev. 2025;83(3):448-465. doi:10.1093/nutrit/nuae113. PMID:39225983
  3. Sahebkar A, Soranna D, Liu X, Thomopoulos C, Simental-Mendia LE, Derosa G, et al. A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure. J Hypertens. 2016;34(11):2127-35. doi:10.1097/HJH.0000000000001049. PMID:27512971
  4. U.S. Department of Agriculture, Agricultural Research Service. Seeds, hemp seed, hulled. FoodData Central, SR Legacy, FDC ID 170148. Published April 1, 2019.
  5. U.S. Department of Agriculture, Agricultural Research Service. Seeds, chia seeds, dried. FoodData Central, SR Legacy, FDC ID 170554. Published April 1, 2019.
  6. U.S. Department of Agriculture, Agricultural Research Service. Seeds, flaxseed. FoodData Central, SR Legacy, FDC ID 169414. Published April 1, 2019.
  7. Mohammadi-Sartang M, Sohrabi Z, Barati-Boldaji R, Raeisi-Dehkordi H, Mazloom Z. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. Nutr Rev. 2018;76(2):125-139. doi:10.1093/nutrit/nux052. PMID:29228348
  8. Hadi A, Askarpour M, Salamat S, Ghaedi E, Symonds ME, Miraghajani M. Effect of flaxseed supplementation on lipid profile: An updated systematic review and dose-response meta-analysis of sixty-two randomized controlled trials. Pharmacol Res. 2020;152:104622. doi:10.1016/j.phrs.2019.104622. PMID:31899314
  9. Mohammadi-Sartang M, Mazloom Z, Raeisi-Dehkordi H, Barati-Boldaji R, Bellissimo N, Totosy de Zepetnek JO. The effect of flaxseed supplementation on body weight and body composition: a systematic review and meta-analysis of 45 randomized placebo-controlled trials. Obes Rev. 2017;18(9):1096-1107. doi:10.1111/obr.12550. PMID:28635182
  10. Axe J, Rubin J. The Biblio Diet. Hachette Book Group; 2025. ISBN 9781546008439. Food list ("Nuts, seeds, and their butters (organic, sprouted, or dry toasted are best)"); nuts section ("about a handful at most a day", ebook p. 104; soaking and low-heat drying); spices (cumin).
  11. Axe J. You Were Lied To About Seed Oils! The Truth About Butter, Tallow & Olive Oil. The Dr. Josh Axe Show. 2026 (refined seed oils at 26:15; pressed seed oils at 26:47; black seed oil at 27:27; fruit oils and 'actual food' at 29:05 to 29:29).
  12. U.S. Department of Agriculture, Agricultural Research Service. Seeds, pumpkin and squash seed kernels, dried. FoodData Central, SR Legacy, FDC ID 170556. Published April 1, 2019.
  13. U.S. Food and Drug Administration. Daily Value on the Nutrition and Supplement Facts Labels.
  14. The Holy Bible, King James Version (Genesis 1:29; Deuteronomy 8:8; Isaiah 28:25). Project Gutenberg eBook #10.
  15. Axe J. Cellular Health EXPERT: How to Build Bulletproof Cells for Energy, Detox & Longevity. The Dr. Josh Axe Show. 2025 (seed rotation at 9:48 to 10:04; "moved away from nuts and seeds" at 10:09).
  16. U.S. Department of Agriculture, Agricultural Research Service. Seeds, sunflower seed kernels, dried. FoodData Central, SR Legacy, FDC ID 170562. Published April 1, 2019.
  17. U.S. Department of Agriculture, Agricultural Research Service. Seeds, sesame seeds, whole, dried. FoodData Central, SR Legacy, FDC ID 170150. Published April 1, 2019.
  18. U.S. Department of Agriculture, Agricultural Research Service. Spices, cumin seed. FoodData Central, SR Legacy, FDC ID 170923. Published April 1, 2019.
  19. Axe J. Healing protocols: the ranked food lists (top 10 foods, or foods that heal) of the 24 protocols in the DrAxe.com protocol library (as of October 12, 2026: flaxseed named on 7, pumpkin seeds on 11, pomegranate on 6, quinoa on 3, chia on 1; sunflower, sesame, hemp, cumin and black seed on none). DrAxe.com; 2026.
  20. U.S. Department of Agriculture, Agricultural Research Service. Quinoa, uncooked. FoodData Central, SR Legacy, FDC ID 168874. Published April 1, 2019.
  21. U.S. Department of Agriculture, Agricultural Research Service. Pomegranates, raw. FoodData Central, SR Legacy, FDC ID 169134. Published April 1, 2019.
  22. Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, et al. Potent antihypertensive action of dietary flaxseed in hypertensive patients. Hypertension. 2013;62(6):1081-9. doi:10.1161/HYPERTENSIONAHA.113.02094. PMID:24126178
  23. Axe J. 7 Foods That Quiet Inflammation Better Than Supplements. The Dr. Josh Axe Show. 2026 (nuts and seeds at 20:27; walnuts, ground flaxseed and pumpkin seeds at 21:14).
  24. Axe J. The Anti-Inflammatory Reset. DrAxe.com; 2026.
  25. Axe J. Hormone Balance for Women: The 90-Day Healing Protocol. DrAxe.com; 2026.
  26. Axe J. The Type 2 Diabetes Protocol. DrAxe.com; 2026.
  27. Saadh MJ, Abosaoda MK, Baldaniya L, Kalia R, Arya R, Mishra S, et al. The Effects of Chia Seed (Salvia hispanica L.) Consumption on Blood Pressure and Body Composition in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Clin Ther. 2025;47(2):168-175. doi:10.1016/j.clinthera.2024.11.012. PMID:39672763
  28. Ayaz A, Akyol A, Inan-Eroglu E, Kabasakal Cetin A, Samur G, Akbiyik F. Chia seed (Salvia Hispanica L.) added yogurt reduces short-term food intake and increases satiety: randomised controlled trial. Nutr Res Pract. 2017;11(5):412-418. doi:10.4162/nrp.2017.11.5.412. PMID:28989578
  29. Simmelink A, Rawl RE, Browne L, Scobey M. Watch it grow: Esophageal impaction with chia seeds. Case Rep Intern Med. 2017;4(2):49. doi:10.5430/crim.v4n2p49.
  30. Jafari A, Mardani H, Faghfouri AH, Fashtali ZM, Hashemi M, Yousefabady MA, et al. Does Nigella sativa supplementation improve cardiovascular disease risk factors? A comprehensive GRADE-assessed systematic review and dose-response meta-analysis of 82 randomized controlled trials. Pharmacol Res. 2025;219:107882. doi:10.1016/j.phrs.2025.107882. PMID:40714301
  31. Farhangi MA, Dehghan P, Tajmiri S, Abbasi MM. The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis: a randomized controlled trial. BMC Complement Altern Med. 2016;16(1):471. doi:10.1186/s12906-016-1432-2. PMID:27852303
  32. Kaatabi H, Bamosa AO, Badar A, Al-Elq A, Abou-Hozaifa B, Lebda F, et al. Nigella sativa improves glycemic control and ameliorates oxidative stress in patients with type 2 diabetes mellitus: placebo controlled participant blinded clinical trial. PLoS One. 2015;10(2):e0113486. doi:10.1371/journal.pone.0113486. PMID:25706772
  33. Axe J. Deep Sleep Protocol. DrAxe.com; 2026.
  34. Axe J. Perimenopause & Menopause: The 90-Day Healing Protocol. DrAxe.com; 2026.
  35. Axe J. The Candida Cleanse Protocol. DrAxe.com; 2026.
  36. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int. 2015;94(3):286-95. doi:10.1159/000362903. PMID:25196580
  37. Axe J. Women NEED to Know This Before Getting on HRT. The Dr. Josh Axe Show. 2026 (flaxseed at 30:40; sesame at 31:13; pumpkin seeds and zinc at 33:51; pumpkin seed butter at 34:14).
  38. Axe J, Cole W. Heal Your Cells. Avery; 2026. ISBN 9798217181353. Chapter 6, "Personalized Nutrition for Cellular Healing," Ancient Grains and Legumes section (sprouting and fermenting reduce phytic acid; quinoa's nine essential amino acids).
  39. Huang L, Li X, Zou M, Zeng H, Wu S, Liang Y, et al. Quinoa is more effective than other whole grains in the management of impaired glucose tolerance: a randomized controlled trial. Food Funct. 2025;16(2):763-773. doi:10.1039/d4fo04557b. PMID:39784492
  40. Pourshahidi LK, Caballero E, Osses A, Hyland BW, Ternan NG, Gill CIR. Modest improvement in CVD risk markers in older adults following quinoa (Chenopodium quinoa Willd.) consumption: a randomized-controlled crossover study with a novel food product. Eur J Nutr. 2020;59(7):3313-3323. doi:10.1007/s00394-019-02169-0. PMID:31919583
  41. Axe J. Acid Reflux & GERD Protocol. DrAxe.com; 2026. Top 10 reflux-friendly foods (rice & quinoa), p. 22.
  42. Axe J. The Breast Cancer Support Protocol. DrAxe.com; 2026. Foods that heal (fiber-rich legumes and whole grains: lentils, chickpeas and quinoa), p. 16.
  43. Axe J. The Integrative Cancer Support Guide. DrAxe.com; 2026. Nutrition support (whole grains: oats, quinoa and brown rice), p. 9.
  44. Richmond K, Williams S, Mann J, Brown R, Chisholm A. Markers of cardiovascular risk in postmenopausal women with type 2 diabetes are improved by the daily consumption of almonds or sunflower kernels: a feeding study. ISRN Nutr. 2013;2013:626414. doi:10.5402/2013/626414. PMID:24959542
  45. She Y, Jia K, Cardillo A, Shamloo M, León AS, Liu X, et al. The effect of hemp product consumption on blood fatty acid profiles and cardiovascular disease risk factors: results of a randomized, double-blind, crossover clinical trial. Food Funct. 2026;17(6):2884-2892. doi:10.1039/d5fo04672f. PMID:41782552
  46. Zare R, Heshmati F, Fallahzadeh H, Nadjarzadeh A. Effect of cumin powder on body composition and lipid profile in overweight and obese women. Complement Ther Clin Pract. 2014;20(4):297-301. doi:10.1016/j.ctcp.2014.10.001. PMID:25456022
  47. Hadi A, Mohammadi H, Hadi Z, Roshanravan N, Kafeshani M. Cumin (Cuminum cyminum L.) is a safe approach for management of lipid parameters: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2018;32(11):2146-2154. doi:10.1002/ptr.6162. PMID:30088304
  48. U.S. Department of Agriculture, Agricultural Research Service. Seeds, sesame seed kernels, dried (decorticated). FoodData Central, SR Legacy, FDC ID 169412. Published April 1, 2019.
  49. U.S. Department of Agriculture, Agricultural Research Service. Seeds, sesame butter, tahini, from roasted and toasted kernels (most common type). FoodData Central, SR Legacy, FDC ID 170189. Published April 1, 2019.
  50. Wu WH, Kang YP, Wang NH, Jou HJ, Wang TA. Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in postmenopausal women. J Nutr. 2006;136(5):1270-5. doi:10.1093/jn/136.5.1270. PMID:16614415
  51. Mirmiran P, Bahadoran Z, Golzarand M, Rajab A, Azizi F. Ardeh (Sesamum indicum) could improve serum triglycerides and atherogenic lipid parameters in type 2 diabetic patients: a randomized clinical trial. Arch Iran Med. 2013;16(11):651-6. PMID:24206407
  52. Wichitsranoi J, Weerapreeyakul N, Boonsiri P, Settasatian C, Settasatian N, Komanasin N, et al. Antihypertensive and antioxidant effects of dietary black sesame meal in pre-hypertensive humans. Nutr J. 2011;10:82. doi:10.1186/1475-2891-10-82. PMID:21827664
  53. Axe J. 10 Biblical Superfoods That Can Add Years to Your Life. The Dr. Josh Axe Show, Episode 393. 2026.
  54. Sahebkar A, Ferri C, Giorgini P, Bo S, Nachtigal P, Grassi D. Effects of pomegranate juice on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2017;115:149-161. doi:10.1016/j.phrs.2016.11.018. PMID:27888156
  55. Axe J. Top 10 Bible Foods That Heal: The Biblical Superfoods, Ranked. DrAxe.com. 2026.
  56. Axe J. Seed Oils: Are They Bad? Best & Worst Oils Ranked. DrAxe.com. 2026.
  57. Baker EJ, Miles EA, Burdge GC, Yaqoob P, Calder PC. Metabolism and functional effects of plant-derived omega-3 fatty acids in humans. Prog Lipid Res. 2016;64:30-56. doi:10.1016/j.plipres.2016.07.002. PMID:27496755
  58. Axe J. Proven Ways To Prevent Alzheimer's Before It's Too Late. The Dr. Josh Axe Show. 2025 (ALA conversion and wild-caught fish at 3:24).
  59. Naghshi S, Aune D, Beyene J, Mobarak S, Asadi M, Sadeghi O. Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies. BMJ. 2021;375:n2213. doi:10.1136/bmj.n2213. PMID:34645650
  60. Kuijsten A, Arts IC, van't Veer P, Hollman PC. The relative bioavailability of enterolignans in humans is enhanced by milling and crushing of flaxseed. J Nutr. 2005;135(12):2812-6. doi:10.1093/jn/135.12.2812. PMID:16317125
  61. Austria JA, Richard MN, Chahine MN, Edel AL, Malcolmson LJ, Dupasquier CM, et al. Bioavailability of alpha-linolenic acid in subjects after ingestion of three different forms of flaxseed. J Am Coll Nutr. 2008;27(2):214-21. doi:10.1080/07315724.2008.10719693. PMID:18689552
  62. Schlemmer U, Frølich W, Prieto RM, Grases F. Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis. Mol Nutr Food Res. 2009;53 Suppl 2:S330-75. doi:10.1002/mnfr.200900099. PMID:19774556
  63. Hambidge KM, Miller LV, Westcott JE, Krebs NF. Dietary reference intakes for zinc may require adjustment for phytate intake based upon model predictions. J Nutr. 2008;138(12):2363-6. doi:10.3945/jn.108.093823. PMID:19022958
  64. Coulman KD, Liu Z, Hum WQ, Michaelides J, Thompson LU. Whole sesame seed is as rich a source of mammalian lignan precursors as whole flaxseed. Nutr Cancer. 2005;52(2):156-65. doi:10.1207/s15327914nc5202_6. PMID:16201847
  65. Haggans CJ, Hutchins AM, Olson BA, Thomas W, Martini MC, Slavin JL. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Nutr Cancer. 1999;33(2):188-95. doi:10.1207/S15327914NC330211. PMID:10368815
  66. Nagarajan DR, Mani Jacob D, Munir Mufti M, Rajesh S, Dube R. Efficacy of Seed Cycling as an Integrative Therapy for Premenstrual Syndrome and Polycystic Ovary Syndrome in Reproductive-Aged Women: A Systematic Review. Cureus. 2025;17(8):e90997. doi:10.7759/cureus.90997. PMID:41018334
  67. U.S. Department of Agriculture, Agricultural Research Service. Spices, poppy seed. FoodData Central, SR Legacy, FDC ID 171330. Published April 1, 2019.
  68. U.S. Department of Agriculture, Agricultural Research Service. Nuts, pine nuts, dried. FoodData Central, SR Legacy, FDC ID 170591. Published April 1, 2019.
  69. U.S. Department of Agriculture, Agricultural Research Service. Seeds, watermelon seed kernels, dried. FoodData Central, SR Legacy, FDC ID 169407. Published April 1, 2019.
  70. U.S. Food and Drug Administration. Food Allergies (sesame named the 9th major food allergen by the FASTER Act; requirements apply as of January 1, 2023).
  71. Shah A, Patel N, Dehbozorgi S, Cox AL, Baker MG. Sunflower Seed Allergy: Natural History, Oral Food Challenge Outcomes, and Review of the Literature. J Allergy Clin Immunol Pract. 2026;14(7):1644-1651. doi:10.1016/j.jaip.2026.03.032. PMID:41967675
  72. Özbunar E, Aydoğdu M, Döğer R, Bostancı Hİ, Koruyucu M, Akgür SA. Morphine Concentrations in Human Urine Following Poppy Seed Paste Consumption. Forensic Sci Int. 2019;295:121-127. doi:10.1016/j.forsciint.2018.11.026. PMID:30579243
  73. Peery AF, Strate LL, Stollman N, Mankaney G, Chang JW, Grover S. ACG Clinical Guideline: Colonic Diverticulitis. Am J Gastroenterol. 2026;121(7):1549-1561. doi:10.14309/ajg.0000000000004047. PMID:42390126
Dr. Josh Axe

Dr. Josh Axe, DC, DNM, CNS

Doctor of Natural Medicine · Founder, DrAxe.com

Dr. Axe is a certified doctor of natural medicine, clinical nutritionist, and multiple New York Times bestselling author. He has spent 20+ years in clinical practice helping people heal at the root cause and founded one of the most-visited natural-health platforms in the world.

Read the full bio →

This article is for educational purposes. See our medical disclaimer.