Hyperbaric Oxygen Therapy Benefits, Risks and Side Effects - Dr. Axe

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Hyperbaric Oxygen Therapy Benefits for Specific Healing


Hyperbaric oxygen therapy - Dr. Axe

Our bodies need oxygen to function. When we breath, it’s brought into our lungs and transported by our red blood cells to our bodies. It’s then used to produce energy and sustain life. Researchers discovered that exposure to pure oxygen, at levels much higher than what we are exposed to regularly, can help to treat chronic wounds and infections, decompression sickness, carbon monoxide poisoning and other serious conditions.

Hyperbaric oxygen therapy (HBOT) involves supplying the body’s blood and tissues with pure oxygen in order to promote healing. Hyperbaric medicine was first used in the 1600s when patients went into airtight chambers that could be compressed and decompressed. In the U.S., HBOT was used in the early 20th century to treat the flu and then again in the 1940s to treat decompression sickness among Navy deep sea divers.

Today, hyperbaric oxygen therapy has been deemed effective for several health conditions and serves as a non-invasive adjunctive treatment. But the FDA warns us that it’s not useful for every condition under the sun — as some online sources may lead you to believe. And when hyperbaric oxygen therapy isn’t used properly, for the appropriate conditions, it may actually do more harm than good.

What Is a Hyperbaric Chamber?

A hyperbaric chamber is a pressurized tube or room that provides pure oxygen in air pressure levels that are up to three times higher than average.

As you sit or lie in the chamber, you breath in pure oxygen so that it enters your blood and travels throughout your body, allowing for tissue repair and the restoration of normal body function.


What is Hyperbaric Oxygen Therapy?

Hyperbaric oxygen therapy involves increasing your exposure to pure oxygen in a pressurized room or tube. When you breath inside the hyperbaric chamber, your lungs are able to gather up to three times more oxygen than it would normally, allowing it to enter your blood and promote healing.

Technically speaking, the efficacy of hyperbaric oxygen therapy is due to the physical relationships between gas concentration, volume and pressure. When we breath in 100 percent oxygen at atmospheric pressures of up to 3 atm, this works to raise the amount of oxygen in our blood and tissue. The increased oxygen is then able to control infections, reduce inflammation and swelling, increase collagen deposition and stimulate angiogenesis, or the formation of new blood vessels.

Hyperbaric oxygen therapy has been approved for the treatment of the following conditions:

  • decompression sickness
  • anemia due to severe blood loss
  • carbon monoxide poisoning
  • chronic wounds that don’t respond to conventional treatment
  • radiation wounds or injury
  • thermal burns caused by heat or fire
  • skin grafts
  • serious infections
  • gangrene
  • air or gas embolism, which occurs when bubbles enter a vein or artery
  • arterial insufficiency, which occurs when flow blood slows or stops through arteries

Related: Ozone Therapy: Should It Be Approved for Medicinal Use?

Hyperbaric Oxygen Therapy Benefits

1. Used to Treat Decompression Sickness

Decompression sickness is a condition that sometimes occurs in deep sea divers, mountain climbers or people who work at very high or low altitudes. The condition is caused by bubbles of nitrogen and other gasses forming in the bloodstream, leading to severe joint pain, dizziness and shortness of breath.

Hyperbaric oxygen therapy is used to reduce bubbles in the bloodstream and fill the tissues with oxygen. Research shows that HBO2 therapy is recommended for most decompression sickness cases until the patient is stable.

2. Fights Serious Infections

Hyperbaric oxygen therapy is used in the management of serious infections, like diabetic foot infections, fugal infections, neurosurgical infections, gangrene and necrotizing fascilitis (also known as flesh-eating disease). HBO2 therapy acts as an antibacterial agent by increasing the formation of free oxygen radicals.

It works to restore the bacteria-killing abilities of white blood cells in wounds by increasing tissue oxygen tensions, and studies show that it even works synergistically with a number of antibiotics.

3. Heals Chronic Wounds

Hyperbaric oxygen therapy is sometimes used for the treatment of chronic wounds because it works to improve oxygenation and promote the formation of new blood vessels. Hyperbaric oxygen therapy can also help to decrease inflammation in chronic wounds and decrease the likelihood of negative events, such as amputation, according to research published in Advances in Skin and Wound Care.

HBO2 therapy is most often used to treat wounds caused by diabetes, such as those to the lower extremities, and wounds from radiation therapy. It’s also used to treat complex wounds like leg ulcers, ischemic wounds as a result of blocked blood flow, radiation wounds and surgical wounds.

4. May Improve Neurodegenerative Diseases

HBO2 therapy has shown to improve neurological functions and quality of life for people who are recovering from incidents such as stroke and traumatic brain injury. It is also used to improve the symptoms of some neurodegenerative diseases, including Alzheimer’s.

Recent research published in Neural Regeneration Research suggests that hyperbaric oxygen therapy may be useful in the treatment of Alzheimer’s disease. Researchers found that HBO2 therapy reduced hypoxia and neuroinflammation, and improved behavioral tasks in mice.

5. Used for Carbon Monoxide Poisoning

HBO2 therapy can be used in cases of carbon monoxide poisoning, which displaces oxygen in the bloodstream. Studies have shown that under certain conditions, HBO2 can reduce the risk of brain injury and nerve damage following CO poisoning.

How to Use and Where to Find HBOT

To receive hyperbaric oxygen therapy, you’ll likely visit an outpatient center that has single chambers or multi-person chambers. Chambers made for one person is typically a clear plastic tube. The patient will lie on a table that then slides into the tube. For multi-person chambers, patients typically sit in provided seats and wear a mask that’s hooked up to an oxygen machine. Some chambers even allow patients to listen to music or water TV as they undergo treatment.

A hyperbaric oxygen therapy session can last anywhere from 30 minutes to two hours. And the number of sessions a patient must undergo depends on his or her condition. For the treatment of chronic wounds, 20–40 HBOT sessions may be necessary.


Talk to your healthcare professional about the possibility of using hyperbaric oxygen therapy for your specific condition. If he or she deems it appropriate, your doctor should be able to recommend an outpatient facility that offers this type of therapy. Hyperbaric oxygen therapy is approved by most major health insurance companies when it’s approved for your particular condition. One HBOT session costs about $350, but this depends on the location, and you can expect to pay a copay for each session.

If you are looking to undergo hyperbaric oxygen therapy at home, there are companies that supply portable hyperbaric chambers. It’s important to speak to your healthcare provider about this option and make sure that the portable chamber is safe and regulated.

Risks and Side Effects

What are the side effects of hyperbaric oxygen therapy? When HBOT is used for conditions that have been deemed appropriate by the FDA, it is usually well tolerated with few side effects. However, some patients using hyperbaric oxygen therapy may experience mild side effects like sinus pain, ear pressure and painful joints.

Some patients experience claustrophobia when they’re inside the hyperbaric chambers and people with diabetes may experience a drop in blood sugar during treatment, so they should eat before entering the chamber and monitor their blood glucose levels.

More serious hyperbaric oxygen therapy side effects include difficulty breathing, seizures, paralysis and air embolism, which is when air bubbles enter a vein or artery. Although it’s rare, hyperbaric chambers can be dangerous because they increase the risk of fire, which is due to the chamber’s oxygen-rich environment. But generally, a chamber is a safe environment when it’s handled by a professional with the appropriate training.

According to the FDA, “hyperbaric oxygen therapy has not been proven to be the kind of universal treatment it has been touted to be on some Internet sites. FDA is concerned that some claims made by treatment centers using HBOT may give consumers a wrong impression that could ultimately endanger their health.”

According to the association’s statement, the FDA is concerned that patients may be lead to believe that hyperbaric oxygen therapy is safe and effective for serious medical conditions and they may choose to delay or forgo proven medical therapies. The FDA fears that this may lead to some patients experiencing lack of improvement or even worsening of their existing conditions.

Some conditions that hyperbaric oxygen therapy has not been cleared for include HIV/AIDS, stroke, Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, depression, bell’s palsy, cerebral palsy and brain injury.

Final Thoughts

  • Hyperbaric oxygen therapy involves supplying the body’s blood and tissues with pure oxygen in order to promote healing and relieve decompression sickness.
  • When you breath inside the pressurized hyperbaric chamber, your lungs are able to gather up to three times more pure oxygen than it would normally. The amount of time you spend in a hyperbaric chamber depends on the condition, but generally it will last 30 minutes to two hours.
  • The FDA has approved HBOT for certain conditions, including:
    • air or gas embolism
    • decompression sickness
    • carbon monoxide poisoning
    • gas gangrene
    • anemia due to blood loss
    • thermal burns
    • compromised skin grafts
    • radiation injury
    • chronic wounds

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