Herbs & Spices · Calming herbs

Valerian Root: Sleep Benefits, Dosage, Tea & Side Effects

What valerian root is, what the trials show for sleep, stress, period pain and hot flashes, how to take it as a tea, tincture or capsule, how much to take and who should be careful.

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Evidence-based65 sources citedUpdated October 16, 2026
Published Oct 16, 2026Last updated Oct 16, 2026Editorial policyMedical review policyFact-checking policy
Fresh valerian stems with clusters of tiny white flowers and long green leaves in a wooden bowl on burlap, beside a wooden mortar and pestle
Valerian's small white flowers are the showy part of the plant; the medicine comes from its root.
The Dr. Axe Score™
7.3/10
Overall Dr. Axe Score · Valerian Root

Valerian root scores 7.3 for its long record as a calming herb, placebo-controlled trials on sleep, stress, period pain and hot flashes, and side effects about as common as on placebo.

Scientific Evidence
5.8/10
Four meta-analyses and many placebo-controlled trials; more people sleep better on valerian, while sleep-lab results are mixed.
Traditional Medicine
9.0/10
Used since early Greece and Rome, still official in northern European pharmacopoeias, and recognized by EU regulators.
Clinical Effectiveness
6.6/10
Our judgment: a useful nightly herb for sleep and calm, with results that build over 2 to 4 weeks.
Safety
8.2/10
Side effects similar to placebo in trials; rare liver reports, mostly with other herbs, and withdrawal symptoms after long nightly use.
Why this score?
Why Valerian Root scores 7.3 / 10

    Larger trials of standardized extracts would raise it. Weighting: Evidence 30% · Traditional Medicine 25% · Clinical Effectiveness 25% · Safety 20% (5.8×0.30 + 9.0×0.25 + 6.6×0.25 + 8.2×0.20 = 1.74 + 2.25 + 1.65 + 1.64 = 7.28, shown as 7.3). How we score

    A transparent, weighted index built for supplements. See how it’s calculated →

    Interaction check: Moderate for sedatives and sleep medicines (benzodiazepines, prescription sleep aids, opioids and sedating antihistamines), alcohol, and anesthesia before surgery. Valerian can add to their drowsiness. Interactions are rated separately and don't change the score.

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    Valerian root at a glance

    Valerian root is the dried root of Valeriana officinalis, a calming herb people have used for sleep since early Greece and Rome, and Europe's medicines regulator accepts its dry extract for mild nervous tension and sleep problems on the strength of clinical studies.12 In pooled placebo-controlled trials, more people reported better sleep on valerian than on placebo, and in the newest placebo-controlled trial, people on valerian also slept longer in a sleep lab, while sleep time fell on placebo.34

    • Sleep: in a placebo-controlled trial of 80 adults with mild insomnia, 72 of whom finished, 200 mg of extract nightly for 8 weeks lowered a standard sleep-quality score by 2.05 points, against 0.09 on placebo4
    • Timing: its effect builds over 2 to 4 weeks of nightly use2
    • Tea: 0.3 to 3 grams of dried root steeped in about 2/3 cup of boiling water, half an hour to an hour before bed2
    • Be careful with: sedatives and sleep medicines, alcohol, surgery, pregnancy and breastfeeding, and children under 12

    Valerian is one of the sleep herbs in my free Deep Sleep Protocol.5

    Open a bag of dried valerian root and the smell reaches you before anything else. It's strong and unmistakable, and it comes from isovaleric acid, released as compounds in the root called valepotriates break down.6 People have put up with that smell for a very long time because of what the root does, and today they take it mostly for sleep, stress and nervous tension.1

    I suggest valerian for sleep, and on my show I've said valerian root can be great, along with passionflower, skullcap, magnolia and jujube.78

    To improve sleep, take 1 teaspoon of a valerian tincture or fluid extract daily. It can take two weeks for the effect to take hold. Once sleep improves, keep taking valerian for two to six weeks.Dr. Josh Axe, DC, DNM, CNSFrom Ancient Remedies (2021), p. 126

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    Did you know?

    • Valerian root has served as a mild sedative in many cultures, and Valeriana officinalis still holds official status in the pharmacopoeias of northern Europe.9

    • In 2007, a weekly national TV health program in Norway randomized 434 viewers with insomnia into a placebo-controlled valerian trial run entirely over the internet.10

    • When researchers offered 100 domestic cats four plants, about half of the cats responded to valerian root, the same kind of reaction catnip sets off in many cats.11

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    What is valerian root?

    Quick answer

    Valerian root is the dried root of Valeriana officinalis, a perennial herb, taken as a tea, tincture, capsule or tablet to ease nervous tension and help you sleep.42 Its signature compound is valerenic acid, found in the root's essential oil, alongside a group of compounds called valepotriates.9

    The root's makeup varies a lot from plant to plant, shaped by genetics and growing conditions, which is one reason products differ and why valerenic acid is used as a marker to measure and standardize them.912

    Valerenic acid
    Essential oil

    A compound characteristic of this species and the usual marker for standardizing extracts; in lab tests it fine-tunes the brain's receptors for GABA, a calming messenger.913

    Valepotriates
    Iridoids

    Unstable compounds with calming activity that act as prodrugs, meaning they turn into other active compounds; as they break down in the dried root, they release the isovaleric acid behind valerian's smell.96

    A lignan and GABA itself
    Other constituents

    The lignan hydroxypinoresinol binds benzodiazepine receptors in lab tests, and water extracts of the root carry appreciable amounts of GABA.9

    A short history of valerian root

    Valerian's use as medicine reaches back to early Greece and Rome, where it was a remedy for sleeplessness, migraine, fatigue and stomach cramps.1 Europe has kept that tradition going. The European Medicines Agency recognizes valerian tea, tinctures and powdered root as traditional herbal medicines based on long-standing use, and it accepts one type of dry extract, made with alcohol, for mild nervous tension and sleep problems on the strength of clinical studies, a status called well-established use.2 The agency's plain-language summary notes that valerian root eased mild anxiety as well as other medicines in the comparison studies it reviewed, and some of those studies found it clearly better tolerated.14

    What is valerian root good for?

    Quick answer

    Valerian root's best-studied use is sleep: in pooled placebo-controlled trials, more people reported sleeping better on valerian, and placebo-controlled trials in postmenopausal women, people on dialysis and patients after heart surgery found better sleep scores too.3151617 Trials also suggest benefits for stress, period pain and PMS, hot flashes, thinking after heart surgery and tension headaches.1819202122

    Where the research stands

    We cite 37 human studies of valerian on its own here, from single doses to 8 weeks of nightly use, plus four meta-analyses and a 2024 umbrella review. People taking valerian reported better sleep more often than people on placebo: in a 2010 meta-analysis of 18 trials, they were 1.37 times as likely to report improved sleep in the six trials that asked that question, and the umbrella review found the same benefit in how people rate their own sleep.2324 In the reviews, measured outcomes haven't shown the same gap: in 10 of the 18 trials, the time it took to fall asleep differed by 0.70 minutes on average between valerian and placebo, a difference too small to rule out chance.2324 The trials tested whole dried root, water extracts and alcohol extracts at different strengths, so each study below is described with the form it tested.

    Valerian root benefits, graded by evidence (updated October 2026). Labels are editorial judgments that compare valerian's uses with each other; they aren't formal certainty ratings.
    UseEvidenceWhat was studiedWhat the research shows

    Sleep quality

    Mixed

    Extracts and dried root, 200 to 1,215 mg a day

    1.8 times as likely to report better sleep in one pooled analysis, and 1.37 times in another323

    Sleep with a health condition

    Emerging

    530 mg capsules nightly, 4 weeks to 1 month

    Better sleep scores on dialysis, after bypass surgery and on an HIV medicine161725

    Stress and anxiety

    Mixed

    Single 100 mg doses; extracts for 1 to 4 weeks

    Calmer during dental surgery, 85% vs. 45% on placebo; no difference in a 4-week stress trial1826

    Period pain and PMS

    Emerging

    255 mg three times a day, or 530 mg twice a day

    About 1 point less period pain on a 0-to-10 scale than comparison treatments across 5 trials2719

    Hot flashes

    Emerging

    Root capsules three times a day, or 530 mg twice a day, for 2 months

    Milder hot flashes than placebo by 4 to 8 weeks2820

    Thinking after heart surgery

    Emerging

    530 mg root extract twice a day, 8 weeks

    Thinking-test scores held steady, while they dropped on placebo21

    Tension headaches

    Emerging

    Two 530 mg root-extract capsules daily after dinner, 1 month

    Less headache impact, disability and severity than placebo22

    How valerian root works in your body

    Valerian's calming effect runs through GABA, your brain's main calming messenger. Steps 3 and 4 come from lab and mouse studies; steps 2, 5 and 6 were measured in people.

    1The root carries valerenic acid

    Valerian root's essential oil holds valerenic acid, a compound characteristic of this species, along with valepotriates and other calming compounds.9

    2It reaches your blood in 1 to 2 hours

    After a single 600 mg dose in six healthy adults, valerenic acid peaked in the blood at 1 to 2 hours in five of them and had a half-life of about 1.1 hours, a timeline that fits taking valerian 30 minutes to 2 hours before bed.29

    3It tunes the brain's calming receptors

    In lab tests, valerenic acid made certain GABA receptors respond to less GABA, acting at a different site from the one benzodiazepine drugs use.13

    4That receptor carries its calming effect

    Valerenic acid eased anxious behavior in mice, and the effect disappeared when the mice carried a single-point change in that receptor.30

    5Brain activity shifts in people

    In 15 healthy adults who each tried valerian and a placebo, a single 900 mg dose quieted a measured excitatory circuit in the brain at 1 hour, back to baseline by 6 hours; in 64 stressed adults, 4 weeks of extract raised a pattern of brain-wave coherence that tracked with easing anxiety.3126

    6Deep sleep builds over two weeks

    In 16 adults with insomnia who each tried valerian and a placebo, slow-wave, or deep, sleep improved after 14 nights of valerian but not after a single dose.32

    That timeline explains how valerian is best used: nightly, timed before bed, and given a couple of weeks to settle in.

    Valerian root benefits, ranked by evidence

    Ranked by the weight of human research, valerian does the most for sleep quality and calm under stress, with encouraging results for period pain, hot flashes, thinking after heart surgery and tension headaches.

    1

    Better sleep quality

    Mixed evidenceHuman studyMeta-analyses and placebo-controlled RCTs · 14 to 434 people

    Across six placebo-controlled trials that asked whether sleep improved, people taking valerian were 1.8 times as likely to say yes, and in the newest placebo-controlled trial, of 80 adults with mild insomnia, 200 mg of extract nightly for 8 weeks lengthened total sleep time by 75.21 minutes in the 20 on valerian who were tested in a sleep lab, while it fell on placebo.34 The full set of trials is in the sleep section below.

    Study takeaway: in the newest trial, sleep-lab sleep time rose about 75 minutes on valerian and fell on placebo.

    2

    Calm under stress

    Mixed evidenceHuman studyPlacebo-controlled RCTs and a controlled lab study · 20 to 64 people

    In 20 young adults who each tried valerian and a placebo before wisdom-tooth surgery, a single 100 mg dose left 85% calm and relaxed by the researcher's rating, against 45% on placebo.18 Another lab study split 54 healthy adults into three groups, and after a week, the 18 on valerian reacted to a stress test with a smaller jump in heart rate and systolic blood pressure than before they started.33 The stress section below covers the full set of trials.

    Study takeaway: a single dose before dental surgery nearly doubled the share of patients rated calm.

    3

    Period pain and PMS

    Emerging evidenceHuman studyMeta-analysis of 5 trials · placebo-controlled RCTs of 100 students each

    In a placebo-controlled trial of 100 students with painful periods, valerian at 255 mg three times a day, taken for the first 3 days of each period over two cycles, lowered pain more than placebo, though pain fell in both groups and other period symptoms, apart from fainting, didn't differ.19 A 2025 meta-analysis of five trials with 408 young women found period pain about 1 point lower on a 0-to-10 scale on valerian than in the comparison groups, which took placebo or anti-inflammatory pain relievers, though results varied a lot from trial to trial.27 For PMS, in a placebo-controlled trial of 100 students who took 530 mg capsules twice a day for the last 7 days of three cycles, emotional, behavioral and physical symptoms fell on valerian, and the total symptom score dropped from 106.07 to 41.30, while on placebo it didn't change significantly (132.17 to 125.06).34 For more ways to ease cramps, see natural relief for period cramps.

    Study takeaway: valerian eased period pain more than placebo in two cycles of use.

    4

    Fewer, milder hot flashes

    Emerging evidenceHuman study2 placebo-controlled RCTs · 68 and 60 women

    In a placebo-controlled trial in which 68 of 76 women in menopause finished, capsules of ground valerian root three times a day for 8 weeks lowered the average hot-flash severity score from 9.82 to 5.23, while it stayed near 10 on placebo (9.96 to 9.86), and the average number of hot flashes fell from 7.91 to 4.83, against 7.73 to 7.75 on placebo.28 In another, of 60 postmenopausal women aged 45 to 55, 530 mg twice a day lowered hot-flash severity compared with placebo at 1 and 2 months and frequency at 2 months.20 Valerian also improved sleep after menopause, as the sleep section shows; see natural ways to relieve menopause symptoms and the free Perimenopause & Menopause protocol.

    Study takeaway: hot flashes were milder than on placebo within 4 weeks in two trials.

    5

    Thinking after heart surgery

    Emerging evidenceHuman studyPlacebo-controlled RCT · 61 adults having bypass surgery

    In a placebo-controlled trial of 61 adults aged 30 to 70 having heart bypass surgery, 530 mg of valerian root extract every 12 hours for 8 weeks kept scores on a standard 30-point thinking test steady: they went from 27.03 before surgery to 26.52 at day 10 and 27.45 at 2 months, while on placebo they fell from 27.37 to 24 and were 24.83 at 2 months. Valerian lowered the odds of a measurable decline in thinking by about 89%.21

    Study takeaway: thinking-test scores held steady after heart surgery on valerian and dropped on placebo.

    6

    Tension headaches

    Emerging evidenceHuman studyPlacebo-controlled RCT · 88 adults

    In a placebo-controlled trial of 88 adults with tension-type headaches, two 530 mg capsules of valerian root extract daily after dinner for a month lowered headache impact on daily life to a score of 51.2, against 57.0 on placebo, with less disability and lower severity, 3.5 against 5.1.22

    Study takeaway: headache severity scored 3.5 on valerian, against 5.1 on placebo, after a month.

    Does valerian root help you sleep?

    Quick answer

    Yes, for many people. Across placebo-controlled trials, people taking valerian were 1.8 times as likely to report better sleep, and in the newest placebo-controlled trial, of 80 adults with mild insomnia, 200 mg of extract nightly for 8 weeks improved sleep scores, the time it took to fall asleep and total sleep time more than placebo.34 Its effect builds over 2 to 4 weeks of nightly use.2

    What the newest trial found

    The newest trial, published in 2024, randomized 80 adults aged 18 to 50 with mild insomnia to 200 mg of a valerian root extract standardized to 2% valerenic acid or a placebo, taken 1 hour before bed for 8 weeks; neither the people nor the researchers knew who got what, and 72 finished. The trial was funded by the extract's maker.4

    Their score on the Pittsburgh Sleep Quality Index, a standard questionnaire that runs from 0 to 21, where lower means better sleep, fell 2.05 points on valerian and 0.09 points on placebo. On a wrist sleep tracker, the valerian group fell asleep 48.03 minutes faster than at the start, against 11.73 minutes faster on placebo, and slept 56.31 minutes longer, against 2.33. In 20 people from each group who also slept a night in a sleep lab, total sleep time rose 75.21 minutes on valerian and fell 74.58 minutes on placebo, while deep sleep and REM sleep didn't differ between the groups. Side effects showed up in 3 of 40 people on valerian and 5 of 40 on placebo, all mild and none judged related to the capsules.4

    Sleep-quality score: down 2.05 points on valerian extract, 0.09 on placebo

    Sleep-quality score: down 2.05 points on valerian extract, 0.09 on placebo72 adults with mild insomnia · 200 mg nightly · 8 weeks. Valerian root extract: 2.05 point drop in PSQI; Placebo: 0.09 point drop in PSQI72 adults with mild insomnia · 200 mg nightly · 8 weeks
    2.05 point drop in PSQI
    VALERIAN ROOT EXTRACT
    0.09 point drop in PSQI
    PLACEBO
    Source: Chandra Shekhar et al. · Advances in Therapy, 2024 [4]Average drop in the Pittsburgh Sleep Quality Index after 8 weeks. The scale runs from 0 to 21, and a bigger drop means better sleep.

    Trials in women and in people with health conditions

    In a placebo-controlled trial of 100 postmenopausal women aged 50 to 60 with insomnia, 530 mg of concentrated valerian extract twice a day for 4 weeks improved sleep-quality scores more than placebo, and 30% of the women on valerian improved their sleep quality, against 4% on placebo; neither the women nor the researchers knew who got what.15 It's a trial I've cited on my show when talking about herbs that help sleep.35

    Valerian has also helped people whose health conditions disturb their sleep. In 39 adults on hemodialysis for kidney failure who each tried valerian and a placebo, 530 mg of dried valerian root 1 hour before bed for 1 month lowered their sleep-quality score by 7.6 points, against 3.2 points on placebo, during the first month of the trial.16

    Dialysis patients' sleep-quality score: down 7.6 points on valerian root, 3.2 on placebo

    Dialysis patients' sleep-quality score: down 7.6 points on valerian root, 3.2 on placebo39 adults on hemodialysis · 530 mg dried root nightly · 1 month · each person tried both. Valerian root: 7.6 point drop in PSQI; Placebo: 3.2 point drop in PSQI39 adults on hemodialysis · 530 mg dried root nightly · 1month · each person tried both
    7.6 point drop in PSQI
    VALERIAN ROOT
    3.2 point drop in PSQI
    PLACEBO
    Source: Tammadon et al. · Oman Medical Journal, 2021 [16]First month of the trial, before the groups switched treatments: 19 people on valerian, 20 on placebo. A bigger drop means better sleep.

    In a placebo-controlled trial of 72 people recovering from heart bypass surgery, 530 mg valerian capsules for 30 nights improved overall sleep quality, the time it took to fall asleep, sleep duration and daytime function more than placebo capsules, and clotting tests didn't change.17 And in a pilot placebo-controlled trial of 51 adults starting efavirenz, an HIV medicine known for side effects on sleep and mood, 530 mg nightly for 4 weeks improved sleep and anxiety more than placebo.25

    Valerian's sleep research goes back decades. In a 1982 study, 128 people each took a 400 mg water extract of valerian root, a commercial valerian-containing product and a placebo, in coded samples on different nights; the water extract helped them fall asleep faster and sleep better by their own ratings, especially people who saw themselves as poor sleepers.36 In a sleep-lab study of 16 adults with insomnia who each tried valerian and a placebo, deep sleep began sooner on valerian after 14 nights than on placebo and filled more of the night than at the start, while a single dose made no difference; sleep efficiency, the main measure, improved on both. Side effects were reported 3 times during the valerian weeks and 18 times during placebo.32 In a placebo-controlled pilot study of 14 older poor sleepers, 405 mg three times a day for a week also increased deep sleep in the lab, though their own ratings of sleep quality didn't change.37

    Trials with smaller or no differences

    Other placebo-controlled trials found no clear gap between valerian and placebo on their main measures:

    • A 2-week trial of 434 adults: In the Norwegian trial run through a TV health program, 405 of the 434 people randomized were analyzed. 600 mg of extract nightly improved sleep quality by at least the amount the researchers counted as meaningful in 28.7% of people, against 21.2% on placebo, a gap that could have been chance; asked at the end how they'd slept overall, 9.1% of people on valerian rated their sleep better or much better, against 3.7% on placebo, a difference unlikely to be chance.10
    • Older women: In 16 women with insomnia, average age 69, who each tried 300 mg of concentrated extract and a placebo for 2 weeks, sleep in the lab, on a wrist tracker and in their own ratings didn't differ.38
    • Single nights: In 16 adults aged 50 to 64 who each tried 300 mg, 600 mg and a placebo on single nights in a sleep lab, no sleep or morning-test measure changed.39
    • Cancer treatment: In 227 adults undergoing cancer treatment, 119 of whom could be evaluated, 450 mg 1 hour before bed for 8 weeks didn't change the main sleep score more than placebo, though people on valerian reported less fatigue and less trouble sleeping in additional analyses.40
    • Anxiety with insomnia: In an internet-based trial of adults with anxiety and insomnia, 135 took valerian and 135 a placebo for 28 days, and their insomnia scores improved by about the same amount, 0.4 points apart.41
    • Falling asleep at home: In a 4-week placebo-controlled trial led by researchers at a valerian-hops maker, 500 mg of valerian extract on its own didn't shorten the time to fall asleep on a home sleep recorder more than placebo did.42

    What the pooled analyses show

    A 2006 review of 16 placebo-controlled trials with 1,093 people found that those taking valerian were 1.8 times as likely to report better sleep, across the six trials that asked that question, though the authors saw signs that some trials with negative results went unpublished.3 A 2010 meta-analysis of 18 placebo-controlled trials pointed the same way: in its six trials with a yes-or-no sleep question, people on valerian were 1.37 times as likely to report improved sleep.23 A 2020 review found that the form matters. In the four trials of whole dried root, the effect on sleep quality was about eight times the size seen in the six trials of extracts (0.83 against 0.10), though the result across all 10 trials together could have been chance.6 A 2025 scoping review of 51 trials of over-the-counter sleep products in adults named valerian and melatonin as the most studied, with substantial evidence for their effectiveness and safety.43

    How to get the most from valerian for sleep

    Take it every night and give it time. European regulators call valerian's effect gradual and recommend 2 to 4 weeks of continued use, which matches my advice that it can take two weeks for the effect to take hold.27

    Build a steady circadian rhythm around it, too. In my Deep Sleep Protocol, I note that every sleep nutrient works better with a fixed wake time, morning light and a cool, dark room, because the rhythm is the multiplier.5 Sleep is medicine, and I want you getting about 8 hours a night, at least 7, ideally with 90 minutes to 2 hours of that as deep sleep.44 For long-standing insomnia, my protocol also points to cognitive behavioral therapy for insomnia (CBT-I), which major guidelines recommend first because its benefits last after treatment stops.5 Valerian fits alongside it, along with the basics in sleep hygiene and other natural sleep aids.

    Bloodwork that can explain restless nights

    My Deep Sleep Protocol ranks a few blood tests as supporting checks, because low iron, thyroid shifts, blood sugar swings and a stressed cortisol rhythm can all wake you at night.5 Review your numbers with your practitioner.

    • Ferritin: Your iron stores. The protocol links a ferritin result under 75 ng/mL to restless legs.
    • TSH: A first check on your thyroid.
    • Morning cortisol and fasting glucose: Your main stress hormone and your blood sugar, two other common drivers of night waking.

    See the cellular bloodwork panel

    Have results? Analyze them free →

    Can valerian root ease stress and anxiety?

    Quick answer

    It may, especially in stressful moments. In a placebo-controlled study of 20 young adults who each had two wisdom teeth removed on separate days, a single 100 mg dose of valerian an hour before surgery left 85% calm and relaxed by the researcher's rating, against 45% after a placebo.18 In longer trials, results are mixed: a 4-week stress trial found no gap with placebo, while anxiety eased more than on placebo in people on dialysis and in adults starting an HIV medicine.261625

    In that dental study, the patients, aged 17 to 30, took valerian before one surgery and a placebo before the other, and neither they nor the researchers knew which was which. The surgeon's ratings pointed the same way, but the gap was too small to rule out chance, and 55% of the patients said they felt more comfortable during the valerian surgery, against 25% for the placebo one. Sleepiness was reported by 45% after valerian and 35% after placebo, a difference that wasn't significant.18

    Rated calm and relaxed during surgery: 85% on valerian, 45% on placebo

    Rated calm and relaxed during surgery: 85% on valerian, 45% on placebo20 young adults · 100 mg one hour before surgery · each person tried both. Valerian: 85 % rated calm; Placebo: 45 % rated calm20 young adults · 100 mg one hour before surgery · eachperson tried both
    85 % rated calm
    VALERIAN
    45 % rated calm
    PLACEBO
    Source: Pinheiro et al. · Journal of Pharmacy & Bioallied Sciences, 2014 [18]Share of patients the researcher rated calm and relaxed during the extraction. Higher is better.

    Valerian also softens the body's stress response. In a lab study of 54 healthy adults, the 18 who took valerian for a week had a smaller rise in systolic blood pressure and heart rate during a stressful color-and-word task than they'd had a week earlier, and they felt less pressure, while the 18 untreated controls didn't change.33 In the dialysis trial above, scores for how anxious people felt in the moment fell 14.7 points on valerian, against 7.3 on placebo, in the first month.16

    In a placebo-controlled trial of 64 adults under psychological stress, 100 mg of extract three times a day for 4 weeks improved anxiety and stress scores, but no more than placebo did, though brain-wave measures shifted only in the valerian group.26 In a placebo-controlled pilot trial of 36 adults with generalized anxiety disorder, a valepotriate-rich valerian extract for 4 weeks didn't differ from placebo on the main anxiety scale, though it eased the scale's mental-symptom score within its own group, as diazepam did.45 A Cochrane review found that single trial and called the evidence for anxiety disorders too thin to draw conclusions.46

    Valerian is one of my top five remedies for anxiety because it improves sleep, at 1 teaspoon of tincture a day.7 For more calming options, see natural remedies for anxiety, stress relievers and cortisol levels.

    Valerian root vs. sleep and anxiety medicines

    In two trials of adults with insomnia, valerian extract gave similar results for sleep quality to oxazepam, a benzodiazepine sleep medicine, with fewer side effects in the larger one.4748 In other head-to-head trials, the drug did better on some measures.

    ComparisonWho and how longDosesResultSide effects

    Valerian extract vs. oxazepam

    202 adults with insomnia, 6 weeks, no placebo group

    600 mg vs. 10 mg a day

    Worked as well as oxazepam for sleep quality, in a trial designed to test that47

    28.4% vs. 36.0% had side effects, all mild to moderate

    Valerian extract vs. oxazepam

    75 adults with insomnia, 4 weeks, no placebo group

    600 mg vs. 10 mg, as two tablets 30 minutes before bed

    Similar results; both improved sleep quality48

    2 vs. 3 stopped for possible side effects

    Valerian vs. midazolam before wisdom-tooth surgery

    20 anxious adults, single doses, each person tried both

    100 mg vs. 15 mg

    Midazolam lowered heart rate, blood pressure and breathing rate more; valerian gave comfort with less sleepiness49

    Sleepiness was the most common with both

    Valerian vs. gabapentin

    40 adults on dialysis with restless legs, 1 month each, each person tried both

    Each taken 1 hour before bed

    Gabapentin eased restless legs more; sleep quality was similar50

    —

    Valepotriate extract vs. diazepam

    36 adults with generalized anxiety, 4 weeks

    81.3 mg vs. 6.5 mg a day

    No difference between groups on the main anxiety scale; long-standing anxiety scores fell only on diazepam4546

    No difference in side effects

    In next-morning tests, valerian didn't cause the sedation several sleep drugs did; if you take a sleep medicine or a benzodiazepine, read the safety section below before adding valerian.

    How to take valerian root: tea, tincture or capsules

    Quick answer

    Take valerian half an hour to 2 hours before bed, as a tea of 0.3 to 3 grams of dried root, a tincture or fluid extract, or capsules or tablets of dried root or extract, and keep it up nightly for 2 to 4 weeks.229 Whichever form you choose, take it every night.

    Tea

    Dried, cut root steeped in boiling water; the European Medicines Agency recognizes 0.3 to 3 g in 150 mL as a traditional sleep aid.2

    Tincture or fluid extract

    Liquid extracts in alcohol; I suggest 1 teaspoon a day for sleep.7

    Dried root capsules

    Powdered whole root; the dialysis trial used 530 mg capsules of dried root, 1 hour before bed.16

    Dry extract tablets

    Concentrated alcohol extracts; 400 to 600 mg per dose is the EU-recognized amount, and sleep trials used 200 to 1,215 mg a day.241037

    To make the tea, pour about 2/3 cup (150 mL) of boiling water over 0.3 to 3 grams of dried, cut root, cover it, let it steep, then strain it, and drink it half an hour to an hour before bed.2 If you'd like it sweeter, add a little raw honey, and see herbal tea benefits for other calming cups, such as chamomile and lemon balm.

    Many products pair valerian with hops, lemon balm or passionflower. A blend is its own product, so look for research on that exact combination: in a 4-week placebo-controlled trial, a valerian-hops extract helped people fall asleep faster on a home sleep recorder.42

    When you shop, check for:

    • The plant name on the label: Valeriana officinalis, root.

    • A stated valerenic acid content on extracts; the newest trial's extract was standardized to 2%.4

    • More than one number when you can get it: in a mouse study, two extracts with the same total valerenic acids differed fourfold in calming potency, depending on their ratio of valerenic acid to acetoxyvalerenic acid.51

    • Whole root or extract, by choice: in the 2020 review, trials of whole dried root showed larger effects on sleep quality than trials of extracts.6

    • A single-herb product if you want valerian alone, since many sleep formulas are blends.

    Want help fitting valerian into your evening?

    Ask Dr. Axe AI. Answers are grounded in this library, with sources shown.

    How much valerian root should you take?

    Quick answer

    For sleep, the European Medicines Agency recognizes 400 to 600 mg of dry extract, or a tea made with 0.3 to 3 grams of dried root, half an hour to an hour before bed, and I suggest 1 teaspoon of valerian tincture or fluid extract a day.27 Plan on 2 to 4 weeks of nightly use.2

    UseFormAmountHow long

    Sleep, traditional use

    Tea, dried root

    0.3 to 3 g in 150 mL boiling water, half an hour to an hour before bed

    Nightly; see a practitioner if sleep problems persist2

    Sleep and nervous tension

    Dry extract made with 40 to 70% alcohol

    400 to 600 mg per dose; for tension, up to three times a day

    2 to 4 weeks2

    Sleep, Dr. Axe's amount

    Tincture or fluid extract

    1 teaspoon a day

    Two to six weeks more once sleep improves7

    Mild insomnia

    Extract standardized to 2% valerenic acid

    200 mg, 1 hour before bed

    8 weeks4

    Insomnia after menopause

    Concentrated extract

    530 mg twice a day

    4 weeks15

    Sleep on dialysis

    Dried root capsule

    530 mg, 1 hour before bed

    1 month16

    Period pain

    Capsules

    255 mg three times a day, first 3 days of the period

    2 cycles19

    Hot flashes

    Capsules

    530 mg twice a day

    2 months20

    Tension headaches

    Root extract capsules

    Two 530 mg capsules daily, after dinner

    1 month22

    Time it 30 minutes to 2 hours before bed, the window that fits how fast valerenic acid peaks in the blood.29 The European Medicines Agency allows an earlier dose in the evening when needed, up to four doses a day in all, and advises seeing a practitioner if sleep hasn't improved or has worsened after 2 weeks of continued use.2 In a study of older women, blood levels of valerenic acid varied widely between people, and within the same person from one test to the next, even though the capsules themselves were nearly identical, which may help explain why some people respond more than others.12

    Valerian root side effects & who should be careful

    Quick answer

    Valerian root is well tolerated: in trials, side effects were no more common than on placebo, and the European Medicines Agency lists nausea and stomach cramps as possible side effects.3242 Take care with next-day grogginess, sedatives and sleep medicines, alcohol, surgery, pregnancy and breastfeeding, and children under 12.

    A 2020 review found no severe side effects in trials of people aged 7 to 80.6 NCCIH lists headache, stomach upset, mental dullness, excitability, uneasiness and vivid dreams as possible side effects, and it notes valerian has been used with apparent safety at 300 to 600 mg a day for up to 6 weeks, while its safety over longer stretches hasn't been studied.1 In a reported overdose of about 20 times the recommended amount, symptoms were mild and cleared within 24 hours.52

    Next-morning testing is reassuring. Valerian didn't slow reaction time, alertness or concentration the morning after a single 600 mg dose or after 2 weeks of nightly use, in a placebo-controlled, manufacturer-run trial of 102 volunteers.53 In three placebo-controlled studies of 9 to 14 healthy adults each, single doses of valerian at 400 to 1,800 mg didn't cause measurable sedation or slow tests of coordination and reaction speed, while temazepam, diphenhydramine, triazolam and diazepam did, and in another placebo-controlled trial in which each person tried both, a single 1,600 mg dose didn't change reaction time, field sobriety tests or a driving simulator.54555657

    Good to know before you use valerian
    • Next-day grogginess: A lot of times, valerian leaves people groggy the next day, and that's why I'm not as big a fan of it.44 In the 1982 study in which 128 people each tried every option, a commercial valerian-containing product left people sleepier the next morning, while a water extract of the root didn't.36 If you wake up foggy, take that as your cue to stop, and don't drive or operate machinery when you feel drowsy.2

    • Sedatives, sleep medicines and alcohol: Valerian may add to the drowsiness of sedatives, such as benzodiazepines and prescription sleep aids, and of alcohol, and NCCIH advises against combining it with either.1 In one documented case, a man taking lorazepam who added valerian and passionflower developed hand tremor, dizziness and muscle fatigue.58 In 12 healthy volunteers, 28 days of valerian didn't change four liver enzymes that clear many common drugs, and in another 12, it modestly raised the peak blood level of alprazolam, from 25 to 31 ng/mL, after 14 nights.5960 If you take any of these medicines, don't stop them or swap them for valerian on your own; make changes only with the doctor who prescribes them. As for wine, my Deep Sleep Protocol says to skip it for the first two weeks, then keep it occasional and early;5 on nights you take valerian, leave it out.

    • Before surgery: A JAMA review lists valerian among the herbs that may add to the sedating effect of anesthesia, and in rat brain tissue valerian quieted nerve cells through the same GABA-A receptors many anesthetics act on.6162 Tell your surgical team you take it, and stop it ahead of time as they advise; if you've taken it nightly for months, ask them about easing off gradually rather than stopping all at once.

    • Stopping after long nightly use: Some people have had withdrawal symptoms, including anxiety, irritability, heart disturbances and insomnia, after stopping abruptly following long use; one 1998 case report described heart complications and delirium linked to valerian withdrawal.163 After months of nightly use, ease off gradually rather than stopping all at once.

    • Liver: In very rare cases, liver injury has turned up in people taking valerian, most often alongside other herbs, and a few case reports describe it.16465 If you have liver disease, check with your doctor before using it, and stop and get checked right away if your skin or eyes turn yellow or your urine turns dark.

    • Pregnancy and breastfeeding: Safety hasn't been established, so the European Medicines Agency doesn't recommend valerian during pregnancy or while nursing; wait until you've weaned.21

    • Children: The European Medicines Agency doesn't recommend valerian for children under 12.2

    • When to see a doctor: If you snore and feel sleepy during the day, my Deep Sleep Protocol says to get tested for sleep apnea before relying on any supplement; see how to stop snoring.5 Insomnia with low mood or thoughts of harming yourself needs care right away.

    The bottom line

    Should you try valerian root?

    Yes, if restless nights or a busy mind are part of your life and you can give it a few weeks. Valerian has been a sleep herb since early Greece and Rome, and that long record matters to me, because a remedy that has stayed in use since ancient times reflects what generations of people noticed in their own sleep. Today, more people report better sleep on valerian than on placebo in pooled trials, and trials after menopause, on dialysis and after heart surgery point the same way. The sleep-quality benefit is the best supported, and the period-pain, hot-flash and stress findings are promising.

    Take it nightly, 30 minutes to 2 hours before bed, as a tea of 0.3 to 3 grams of dried root, 400 to 600 mg of dry extract or 1 teaspoon of tincture, and give it 2 to 4 weeks. If you're pregnant or nursing, take a sedative or have surgery coming up, read the safety section first, and stop if you wake up groggy. Then set a steady wake time, get morning light and keep your bedroom cool and dark. Your body was made to repair itself, and night after night of good sleep gives it the time to do that work.

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    Valerian root: frequently asked questions

    What is valerian root good for?

    Valerian root is best known for sleep: in pooled placebo-controlled trials, people taking it were 1.8 times as likely to report better sleep.3 Trials also point to benefits for calm before stressful events, period pain, hot flashes, thinking after heart surgery and tension headaches.1819202122

    Does valerian root help you sleep?

    Yes, for many people: in the newest placebo-controlled trial, of 80 adults with mild insomnia, 200 mg of extract nightly for 8 weeks lowered a standard sleep-quality score by 2.05 points, against 0.09 on placebo, and in the 20 people on valerian who were tested in a sleep lab, total sleep time rose about 75 minutes, while it fell on placebo.4 It works best taken nightly for 2 to 4 weeks.2

    How long does valerian root take to work?

    Plan on about 2 weeks for the effect to take hold and 2 to 4 weeks for its best effect, taken nightly.72 In a sleep-lab study of 16 adults who each tried valerian and a placebo, deep sleep improved after 14 nights of valerian but not after a single dose.32

    Does valerian root make you sleepy the next day?

    It can for some people: next-day grogginess is the main drawback I've talked about with valerian.44 In a placebo-controlled study of 10 healthy young adults, though, single doses up to 1,800 mg didn't slow tests of coordination and reaction speed, and in a placebo-controlled trial of 102 volunteers, 2 weeks of 600 mg nightly didn't slow next-morning reaction time.5653 If you wake up foggy, stop, and don't drive while drowsy.2

    How long does valerian root stay in your system?

    Valerenic acid, a marker compound in valerian, peaked in the blood 1 to 2 hours after a 600 mg dose, stayed measurable for at least 5 hours and had a half-life of about 1.1 hours in healthy adults.29

    How much valerian root should I take for sleep?

    The European Medicines Agency recognizes 400 to 600 mg of dry extract or a tea of 0.3 to 3 grams of dried root, half an hour to an hour before bed, and I suggest 1 teaspoon of tincture or fluid extract a day.27 Sleep trials used 200 to 600 mg of extract as a single dose before bed, and up to 1,215 mg a day split into two or three doses.4101537

    How do you make valerian root tea?

    Pour about 2/3 cup (150 mL) of boiling water over 0.3 to 3 grams of dried, cut valerian root, cover and steep, then strain, and drink it half an hour to an hour before bed.2 Stir in a little raw honey if you'd like it sweeter.

    Can valerian root help with anxiety?

    It may, especially before a stressful event: in 20 young adults who each tried valerian and a placebo before wisdom-tooth surgery, a single 100 mg dose left 85% calm and relaxed by the researcher's rating, against 45% on placebo.18 In a placebo-controlled pilot trial of 51 adults starting an HIV medicine, 530 mg nightly also eased anxiety more than placebo over 4 weeks.25

    Is valerian root safe to take every night?

    Yes, for most adults over several weeks: it has been used with apparent safety at 300 to 600 mg a day for up to 6 weeks.1 After months of nightly use, ease off gradually rather than stopping all at once, since withdrawal symptoms have been reported after abrupt stops.1

    Can valerian root cause a heart attack?

    We found no study linking valerian at normal amounts to heart attacks. One 1998 case report described heart complications and delirium linked to valerian withdrawal, and NCCIH lists heart disturbances among the withdrawal symptoms some people have after stopping abruptly following long use, so taper off after months of nightly use.631 If you have heart disease and take medicines, review valerian with your doctor first.

    What's the difference between valerian root and melatonin?

    They do different jobs: melatonin is a body-clock signal, and my Deep Sleep Protocol uses it short-term at 0.3 to 1 mg for jet lag and a late body clock, while valerian is a calming herb taken nightly for 2 to 4 weeks.52 A 2025 review of over-the-counter sleep products named both among the most studied.43 See melatonin for more.

    Can you take valerian root while pregnant or breastfeeding?

    Skip valerian while you're pregnant or breastfeeding: its safety hasn't been established, and the European Medicines Agency doesn't recommend it for either.21

    Can you drink alcohol with valerian root?

    It's best not to: both can make you drowsy, and NCCIH advises against taking valerian with alcohol.1

    Is valerian root good for women?

    It can be: in placebo-controlled trials, valerian eased period pain more than placebo in 100 students, and 530 mg twice a day made hot flashes milder within a month in 60 postmenopausal women.1920 In a placebo-controlled trial of 100 postmenopausal women with insomnia, 30% on valerian improved their sleep quality, against 4% on placebo.15

    What does valerian root smell like?

    Valerian root has a strong, distinctive smell from isovaleric acid, which is released as compounds called valepotriates break down in the dried root.6

    Why do cats like valerian root?

    Its scent sets off a catnip-like response in many cats: in a study of 100 domestic cats, about half responded to valerian root.11 Researchers tested it as a scent for enrichment, not as something for cats to eat; see catnip.

    Freshness & update log

    October 16, 2026 — Rewrote the page in full. The previous version described benefits for insomnia, anxiety, blood pressure, menstrual cramps, stress and breast cancer, without a reference list. This version ranks the benefits by human trials on sleep, stress, period pain and PMS, hot flashes, thinking after heart surgery and tension headaches, each labeled by design and size, including the sleep trials that found no difference; adds the Dr. Axe Score (7.3) with an interaction check; gives the European Medicines Agency's recognized uses and amounts alongside the doses used in trials and Dr. Axe's tincture amount from Ancient Remedies; drops the blood-pressure and breast-cancer claims, which rested on a lab stress test in healthy people and a single cell study; replaces the earlier pregnancy guidance with the agency's advice to skip valerian while pregnant or nursing; and gathers the cautions on grogginess, sedatives, alcohol, surgery, stopping after long use, the liver, pregnancy and children into one safety section, with 65 references.

    September 23, 2023 — Previous version published.

    References

    1. National Center for Complementary and Integrative Health. Valerian: Usefulness and Safety. Last updated May 2025.
    2. European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Valeriana officinalis L., radix. EMA/HMPC/150848/2015. Adopted 2016 (sections 4.1 well-established use: dry extract, DER 3-7.4:1, ethanol 40-70% V/V; 4.2 posology: single dose 400-600 mg dry extract, up to 3 times daily for nervous tension; to aid sleep half to one hour before bedtime, an earlier evening dose if needed, maximum 4 single doses a day; continued use over 2-4 weeks; herbal tea 0.3-3 g in 150 ml boiling water; not under 12; 4.5 interactions: none reported; 4.6 pregnancy and lactation not recommended; 4.7 may impair driving).
    3. Bent S, Padula A, Moore D, et al. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006;119(12):1005-12. doi:10.1016/j.amjmed.2006.02.026 · PMID:17145239
    4. Chandra Shekhar H, Joshua L, Thomas JV. Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study. Adv Ther. 2024;41(1):246-261. doi:10.1007/s12325-023-02708-6 · PMID:37899385
    5. Axe J. The Deep Sleep Protocol: The 30-Day Healing Protocol. DrAxe.com. 2026 ("How to test — ranked": home sleep apnea test first if you snore and feel sleepy during the day; "Ferritin under 75 is linked to restless legs"; "Morning cortisol, TSH, fasting glucose ... all cause night waking when they're off"; Phase 4 Protect (p. 19): "Retest ferritin and vitamin D at 90 days if they were low"; p. 20 "Top 8 sleep nutrients": magnesium glycinate "The first thing to start"; "Every one works better with a fixed wake time, morning light and a cool, dark room — the rhythm is the multiplier"; "Honorable mentions Lemon balm · Passionflower · Valerian · Saffron · Reishi · Kiwi (2 before bed)"; p. 24 FAQ: wine ("Skip it for the first two weeks, then keep it occasional and early"), snoring ("Get tested before relying on supplements"), "For chronic insomnia, major guidelines recommend CBT-I first, because its benefits last after treatment stops").
    6. Shinjyo N, Waddell G, Green J. Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis. J Evid Based Integr Med. 2020;25:2515690X20967323. doi:10.1177/2515690X20967323 · PMID:33086877
    7. Axe J. Ancient Remedies: Secrets to Healing with Herbs, Essential Oils, CBD, and the Most Powerful Natural Medicine in History. Little, Brown Spark (Hachette Book Group); 2021 (chapter 6, "The Healing Value of Herbs, Spices, and Mushrooms," pp. 109-127, herb entry "Valerian," citing notes 50 and 51; "Prescriptions for 70+ Conditions," Anxiety, p. 219: "2. Valerian. Improves sleep. Take 1 teaspoon of a tincture daily").
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    15. Taavoni S, Ekbatani N, Kashaniyan M, et al. Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial. Menopause. 2011;18(9):951-5. doi:10.1097/gme.0b013e31820e9acf · PMID:21775910
    16. Tammadon MR, Nobahar M, Hydarinia-Naieni Z, et al. The Effects of Valerian on Sleep Quality, Depression, and State Anxiety in Hemodialysis Patients: A Randomized, Double-blind, Crossover Clinical Trial. Oman Med J. 2021;36(2):e255. doi:10.5001/omj.2021.56 · PMID:33936782
    17. Zare Elmi HK, Gholami M, Saki M, et al. Efficacy of Valerian Extract on Sleep Quality after Coronary Artery bypass Graft Surgery: A Triple-Blind Randomized Controlled Trial. Chin J Integr Med. 2021;27(1):7-15. doi:10.1007/s11655-020-2727-1 · PMID:33420602
    18. Pinheiro ML, Alcântara CE, de Moraes M, et al. Valeriana officinalis L. for conscious sedation of patients submitted to impacted lower third molar surgery: A randomized, double-blind, placebo-controlled split-mouth study. J Pharm Bioallied Sci. 2014;6(2):109-14. doi:10.4103/0975-7406.129176 · PMID:24741279
    19. Mirabi P, Dolatian M, Mojab F, et al. Effects of valerian on the severity and systemic manifestations of dysmenorrhea. Int J Gynaecol Obstet. 2011;115(3):285-8. doi:10.1016/j.ijgo.2011.06.022 · PMID:21959068
    20. Jenabi E, Shobeiri F, Hazavehei SMM, et al. The effect of Valerian on the severity and frequency of hot flashes: A triple-blind randomized clinical trial. Women Health. 2018;58(3):297-304. doi:10.1080/03630242.2017.1296058 · PMID:28278010
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    22. Azizi H, Shojaii A, Hashem-Dabaghian F, et al. Effects of Valeriana officinalis (Valerian) on tension-type headache: A randomized, placebo-controlled, double-blind clinical trial. Avicenna J Phytomed. 2020;10(3):297-304 · PMID:32523884
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    24. Valente V, Machado D, Jorge S, et al. Does valerian work for insomnia? An umbrella review of the evidence. Eur Neuropsychopharmacol. 2024;82:6-28. doi:10.1016/j.euroneuro.2024.01.008 · PMID:38359657
    25. Ahmadi M, Khalili H, Abbasian L, et al. Effect of Valerian in Preventing Neuropsychiatric Adverse Effects of Efavirenz in HIV-Positive Patients: A Pilot Randomized, Placebo-Controlled Clinical Trial. Ann Pharmacother. 2017;51(6):457-464. doi:10.1177/1060028017696105 · PMID:28478716
    26. Roh D, Jung JH, Yoon KH, et al. Valerian extract alters functional brain connectivity: A randomized double-blind placebo-controlled trial. Phytother Res. 2019;33(4):939-948. doi:10.1002/ptr.6286 · PMID:30632220
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    36. Leathwood PD, Chauffard F, Heck E, et al. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav. 1982;17(1):65-71. doi:10.1016/0091-3057(82)90264-7 · PMID:7122669
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    42. Koetter U, Schrader E, Käufeler R, et al. A randomized, double blind, placebo-controlled, prospective clinical study to demonstrate clinical efficacy of a fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder. Phytother Res. 2007;21(9):847-51. doi:10.1002/ptr.2167 · PMID:17486686
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    45. Andreatini R, Sartori VA, Seabra ML, et al. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytother Res. 2002;16(7):650-4. doi:10.1002/ptr.1027 · PMID:12410546
    46. Miyasaka LS, Atallah AN, Soares BG. Valerian for anxiety disorders. Cochrane Database Syst Rev. 2006(4):CD004515. doi:10.1002/14651858.CD004515.pub2 · PMID:17054208
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