Nutrition

Amylopectin: What It Is, Foods & How It Affects Blood Sugar

What amylopectin is, how it differs from amylose, which foods carry the most of it, what human trials show for blood sugar and insulin, and how cooking, cooling and the order you eat your food change its effect.

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Evidence-based46 sources citedUpdated October 21, 2026
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Amylopectin - Dr. Axe
Amylopectin at a glance

Amylopectin is the large, branched molecule that makes up most of the starch in rice, potatoes, grains and beans, about 70% to 75% of a typical starch, with the straighter amylose making up most of the rest.12 Once starch is cooked, amylopectin is the part your body turns into glucose fastest.13

  • The starch in waxy foods such as sticky rice is almost all amylopectin,2 while high-amylose rice and breads made from high-amylose wheat and barley raised blood sugar less in human trials4518
  • The food around the starch matters too: how it's milled, cooked and cooled and what you eat with it all change the blood-sugar response14
  • Cooked rice or pasta chilled for a day and then reheated raised blood sugar less than the same food freshly cooked in several trials678
  • The starches to cut are the refined ones, such as white flour, dried cereal and instant oatmeal; whole, properly prepared starches stay on the plate9
  • Eat your protein and vegetables first and the starch last, then take a short walk1011

Most of the starch you eat, in rice, potatoes, bread, oats, corn and beans, is amylopectin, the branched molecule plants build to store energy. Under a microscope, a single starch granule shows growth rings, laid down layer by layer like the rings of a tree, and amylopectin builds those layers as the granule grows.2

Amylopectin is in nearly every starchy food, including the potatoes, rice, beans and sprouted grains I recommend,129 so the useful questions are practical ones: how fast it turns into blood sugar, which foods carry the most of it, and how cooking, cooling and the order you eat your food change its effect. This guide answers each with the human feeding trials and looks at where the claim about "amylopectin A" in wheat comes from.

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How starch is prepared also changes it. When cooked starch cools, part of it turns into resistant starch, a form that escapes digestion in the small intestine and travels on to the colon, where gut bacteria ferment it.1314

Cook your potatoes, let them cool, and eat them later that day or the next day. The type of starch in sweet potatoes and white potatoes, purple sweet potatoes, any type of potato, is fantastic. This type of resistant starch is the number one starch that's going to support butyrate production.Dr. Josh Axe, DC, DNM, CNSFrom The Shocking Reason Your Anxiety, Brain Fog & Bloating May Start in Your Gut, The Dr. Josh Axe Show (2026), at 38:48
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What is amylopectin?

Quick answer

Amylopectin is one of the two molecules that make up starch: a huge, branched chain of glucose that accounts for about 70% to 75% of most starches.1 Amylose, a mostly straight chain, makes up most of the rest. So yes, amylopectin is a starch, the larger part of it, and your digestive enzymes break it back down into glucose.215

Starch is built entirely from glucose, the same sugar your blood carries. Plants join glucose units with two kinds of links: straight links that extend a chain, and branch links that start a new chain off the side.2 Amylose is mostly long, straight chains of a few hundred to a few thousand glucose units. Amylopectin is a large number of short chains, about 18 to 25 glucose units each, tied together by branch points that make up about 5% of its links. That gives it a bushy, tree-like shape and an enormous size, 10 to 100 times the weight of a typical amylose molecule.2 Across plants, amylose makes up anywhere from about 15% to 35% of most starches, and close to none in waxy varieties.2

Plants make amylopectin to store energy. They pack it into tiny granules in seeds, grains, tubers and roots, where its short outer chains pair up into double helices and stack into crystal-like layers.2 That stored glucose is what feeds a grain or bean when it sprouts, and Scripture names the seed-bearing plants as food in its first chapter: "And God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, and every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat" (Genesis 1:29).

Your body takes the chains apart again. Amylase, the starch-digesting enzyme made in your saliva and your pancreas, breaks the chains into smaller pieces, and enzymes on the lining of your small intestine finish the job, releasing glucose into your blood.15 How quickly that happens depends on the starch's structure and on how it was cooked, which the blood-sugar section walks through step by step.

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Amylopectin vs. amylose: what's the difference?

Quick answer

Amylopectin is branched and is digested quickly once cooked; amylose is mostly straight, is digested more slowly and is the part that turns into heat-stable resistant starch when cooked starch cools.113 In a USDA meal test of 25 adults who each ate both, crackers made with starch that was 70% amylose gave a lower blood-sugar peak and less insulin than crackers made with starch that was 70% amylopectin.3

AmylopectinAmylose

Shape

Highly branched, tree-like2

Mostly long, straight chains2

Share of ordinary starch

About 70% to 75%1

About 20% to 25%1

Size

10 million to 100 million daltons2

About 1 million daltons2

Once cooked

Digested quickly1

Digested more slowly1

After cooking and cooling

Re-forms crystals that melt again at 46°C to 65°C (115°F to 149°F) when reheated13

Re-forms into resistant starch that stays stable up to about 120°C (248°F)13

Foods richest in it

Waxy (glutinous or sticky) rice, waxy corn and waxy barley216

High-amylose varieties of rice, wheat, barley and corn1751819

In the 1988 USDA trial, the 12 women and 13 men ate cornstarch crackers carrying 1 gram of starch for every kilogram of body weight. After the amylose crackers, blood sugar peaked lower at 30 minutes and insulin ran lower at 30 and 60 minutes, while total blood sugar over 3 hours didn't differ significantly between the two meals.3 The amylose starch delivered its glucose with less insulin. Rice shows the same pattern: in 33 healthy volunteers who ate three rices, the one with 23% to 25% amylose raised blood sugar less at 30 minutes and called for less insulin over 3 hours than rice with no amylose, even though the rices had the same fiber.20

How much amylose does it take to matter? In a later USDA trial, 25 adults (24 finished) each ate breads made with starch that was 30%, 40%, 50%, 60% or 70% amylose, plus a glucose drink. Insulin was significantly lower only after the 60% and 70% breads, and the researchers concluded that amylose has to make up more than 50% of the starch to lower blood sugar and insulin significantly.21 Ordinary starches sit at about 20% to 25% amylose, and researchers note that the ratio is generally not the deciding factor for blood sugar; the fiber, protein and fat in the meal and the structure of the food weigh in too.1 Cooking counts as well. In a trial in healthy volunteers, three rice varieties with the same amylose content, about 27%, produced different blood-sugar and insulin responses because they cooked differently, and when each was cooked to the same point, their responses matched.22

How does amylopectin affect blood sugar and insulin?

Quick answer

Cooked amylopectin is digested quickly, so starches rich in it raise blood sugar and insulin faster than high-amylose starches do, and in the longer human feeding trials the difference showed up mainly in insulin.319 In a USDA trial of 24 men who ate each starch for 14 weeks, insulin responses were lower after the high-amylose period, while blood-sugar responses were the same on both.19

Here's what happens to starch on its way from your plate to your bloodstream:

1Raw starch is packed tight.

In a raw grain or potato, amylopectin's outer chains sit in crystal-like layers inside each starch granule.2 Starch held this way resists digestion; raw potatoes carry it as type 2 resistant starch.1423

2Cooking opens the granule.

Heat and water make the granule swell, and its crystal structure is lost, a change called gelatinization. Enzymes can then reach the starch.24

3Enzymes turn it into glucose.

Amylase from your saliva and pancreas breaks the chains apart, and enzymes in your small intestine release the glucose.15 Cooked amylopectin is digested faster than amylose.1

4Cooling rebuilds some resistance.

As cooked starch cools, part of it re-forms into resistant starch, mostly from amylose, and that part survives reheating.13

5What escapes feeds your gut.

Resistant starch reaches the colon intact, where bacteria ferment it into short-chain fatty acids such as butyrate.1425

Over weeks, the human trials point to insulin more than to blood sugar. At the USDA's Beltsville research center, 12 men ate a diet with 34% of its calories from starch that was either 70% amylose or 70% amylopectin, 5 weeks of each. A glucose tolerance test after 4 weeks showed no significant difference between the two diets. A test meal after 5 weeks raised blood sugar and insulin less on the amylose diet, though only the insulin total was significantly lower, and fasting triglycerides and cholesterol ran lower during the amylose weeks.26

The longest of these USDA trials ran two 14-week periods. Twenty-four men, 14 of them with high insulin levels, ate foods made with standard cornstarch (70% amylopectin) or high-amylose cornstarch (70% amylose) in place of their usual starches, each man eating both. Insulin responses were lower after the high-amylose period, in the men with high insulin and the other men alike, and the high-amylose foods brought the insulin response of the men with high insulin back to normal. Blood-sugar responses didn't vary with the type of starch, and fasting triglycerides were lower on high-amylose starch throughout.19

Two rat studies found a bigger gap. Rats fed two measured meals a day of a high-amylopectin diet had twice the insulin response to a glucose test of rats on a high-amylose diet within 9 to 12 weeks, and a second study found insulin responses 50% higher after 16 weeks.2728

People have been tested over months, too. In a randomized trial of 68 adults with overweight and prediabetes (61 finished), 45 grams a day of high-amylose corn starch, a resistant starch, was compared for 12 weeks with the same calories from amylopectin starch. HbA1c came out 0.1 percentage point lower on resistant starch, a difference the researchers called clinically insignificant, and insulin sensitivity, insulin secretion and the fat stored in the liver, muscles and around the organs didn't differ between the groups. Resistant starch did lower heart rate by 5 beats a minute and TNF-alpha, an inflammation marker, by 2.1 pg/mL.29

Fullness follows a less clear pattern. In 9 adults who each ate both, high-amylose puffed rice gave 1.5 times as much fullness over 2 hours as low-amylose puffed rice,30 while a 2021 review found too little evidence to say how a starchy food's structure, its amylose ratio included, affects appetite.4

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Which foods are high in amylopectin?

Quick answer

The starch in nearly every starchy food is mostly amylopectin, and in waxy varieties such as glutinous (sticky) rice, waxy corn and waxy barley it's almost entirely amylopectin.1216 Varieties bred for more amylose, such as high-amylose rice, wheat and barley, carry less of it.17518

Wheat, corn, rice and potatoes all sit close to the typical mix of about three parts amylopectin to one part amylose.1 Waxy varieties come from a genetic change that switches off the enzyme that builds amylose, which leaves their starch with little or none.2 Some waxy varieties are grown commercially, notably waxy rice.1

Because amylopectin is in almost every starch, a food's glycemic index, a measure of how much it raises blood sugar compared with pure glucose, tells you more than its amylopectin content alone. Here's how common starchy foods compare in the 2008 international tables:16

FoodAverage glycemic index (glucose = 100)

Glutinous (sticky) rice, cooked in a rice cooker; rice from Thailand, one test in 12 people

98

Rice crackers or crisps

87

Cornflakes

81

Instant oat porridge

79

White wheat bread

75

Whole wheat bread

74

White rice, boiled

73

Brown rice, boiled

68

Table sugar (sucrose)

65

Porridge made from rolled oats

55

Plantain or green banana

55

Sweet corn

52

Lentils

32

Barley

28

Chickpeas

28

Kidney beans

24

Puffed and flaked starches such as rice crackers and cornflakes sit near the top, and beans, lentils, chickpeas and barley near the bottom, a spread the food's structure helps explain: intact grains and intact plant cells slow digestion.4 Waxy barley shows how much the rest of the food matters: boiled waxy barley kernels, whose starch is almost pure amylopectin, measured 22 in one Swedish test in 10 people, against 20 for high-amylose barley.16 Brown rice averages a little lower than white, though in a review of rice studies the gap shrank and varied at the longer cooking times brown rice usually gets.13

Within a single food, amylose content can still make a real difference. In a study of rice products tested in 7 to 8 healthy adults each, waxy rice with 0 to 2% amylose had a glycemic index of 88, close to the 83 and 93 of two rices with about 20% amylose, while a high-amylose rice with 28% amylose came in at 64 and also gave a lower insulin response.1716

Rice glycemic index by amylose content: only the high-amylose rice ran lower

Rice glycemic index by amylose content: only the high-amylose rice ran lowerOne study, 7 to 8 healthy adults per rice · glucose = 100 · white rice, boiled. Pelde white rice (about 20% amylose): 93 glycemic index; Waxy rice (0 to 2% amylose): 88 glycemic index; Calrose white rice (about 20% amylose): 83 glycemic index; Doongara white rice (28% amylose): 64 glycemic indexOne study, 7 to 8 healthy adults per rice · glucose = 100 ·white rice, boiledPelde white rice(about 20%amylose)93 glycemic indexWaxy rice (0 to2% amylose)88 glycemic indexCalrose whiterice (about 20%amylose)83 glycemic indexDoongara whiterice (28%amylose)64 glycemic index
Source: Miller, Pang & Bramall · Am J Clin Nutr, 1992; values as listed in Atkinson et al. · Diabetes Care, 2008 [17, 16]The waxy rice, whose starch is almost pure amylopectin, ran close to the normal-amylose rices; only the high-amylose rice gave a clearly lower response.

Is "amylopectin A" in wheat worse than sugar?

Quick answer

Bread made from ordinary wheat flour and added sugar are both foods to cut,910 but "amylopectin A" isn't the reason: wheat's starch is ordinary starch,1 and sugar's lower glycemic index, 65 against 74 for whole wheat bread, comes from its fructose half.16 "A-type" is the crystal pattern wheat starch shares with corn and rice starch, and cooking breaks that pattern down.24

The idea comes from Dr. William Davis's 2011 book Wheat Belly and his blog, which describe "amylopectin A" as a unique form of carbohydrate in grains that amylase digests very efficiently, and which compare whole wheat bread, at a glycemic index of 72, with table sugar at 59.31321 Here's what the starch research shows:

  • Wheat's starch is ordinary starch, with the same amylose-to-amylopectin mix as other cereals.1

  • "A-type" is a starch-science label. In wheat it names both the crystal pattern its starch shares with corn and rice starch and the larger of its starch granules; potato and high-amylose corn starches are B-type, and pea and cassava starches C-type.24 Baking or boiling with water breaks up those crystals as the starch gelatinizes, so the A pattern belongs to raw flour and is largely lost in baked bread.24

  • Sugar's lower number comes from its fructose. Table sugar is half glucose and half fructose, and fructose barely raises blood glucose;1 its own glycemic index is 15.16

  • How much you eat counts. Researchers point out that the amount of carbohydrate you eat, captured in a food's glycemic load, means more than the glycemic index alone.1

Davis is right that most modern wheat bread is a fast starch: white and whole wheat breads both average in the mid-70s in the table above.16 In The Biblio Diet, organic or sprouted is best for grains and flours and sourdough is best for breads; wheat, rye and barley appear in their sprouted forms only, and white flour, dried cereal and instant oatmeal are on the avoid side.9 Whole-grain sourdough bread has a lower glycemic index than bread made from highly processed white flour, and fermenting the grain makes it easier to digest, which is why sourdough tops my bread list.9 On my show, I've said gluten isn't the villain by itself; the bigger problems are wheat bred to carry more gluten and grains eaten without the traditional sprouting and fermenting.33 If you have celiac disease, the safety section covers which grains to skip.

What makes a starchy food easier on your blood sugar?

Quick answer

In human trials, choosing high-amylose and less-processed starches, eating protein and vegetables before the starch, and chilling cooked starch before reheating it all lowered the blood-sugar response.4116 Resistant starch taken as a supplement for weeks also lowered fasting insulin in a pooled analysis of 13 trials in adults with overweight or obesity.34

Each card below covers one of these levers, ranked by the strength of the human evidence behind it, and each badge grades that evidence.

1

High-amylose varieties

Strong evidenceHuman studyReview of 25 randomized trials · trials of 18 to 38 adults

A 2021 review pooled 25 randomized trials in 369 healthy adults, in which each person tried both foods, and found that starch with more amylose lowered both the blood-sugar and the insulin response after a meal, with little variation among the 6 trials that tested the ratio.4 Bread baked from high-amylose wheat is one example. In 20 healthy adults who each ate 121 grams of bread made from high-amylose and from ordinary wheat, the high-amylose bread cut the blood-sugar response over 3 hours by 39%, 39 against 64 on the trial's measure, and insulin and gut-hormone responses by 24% to 30%, while fullness and cravings didn't differ. Neither the people nor the researchers knew which bread was which, and the trial was run by the wheat's developers with their commercial partner.5 In 38 adults (36 finished), 18 of them with type 2 diabetes, who each tried three breads, bread from a conventionally bred high-amylose barley lowered the blood-sugar response by 41% compared with wheat bread in the people with diabetes and by 28% in those without; one author co-owns a company that makes high-amylose starch.18 In 18 healthy adults (26 enrolled) who each tried three rices without knowing which they were eating, two high-amylose white rices lowered the blood-sugar response compared with short-grain white rice.35

Study takeaway: bread from high-amylose wheat cut the blood-sugar response by 39% in 20 healthy adults.

Bread from high-amylose wheat cut the blood-sugar response by 39%

Bread from high-amylose wheat cut the blood-sugar response by 39%20 healthy adults · 121 g of bread · starch 74% vs 24% amylose · blood sugar over 3 hours. Ordinary wheat bread (24% amylose starch): 64 mmol/L x 3 h; High-amylose wheat bread (74% amylose starch): 39 mmol/L x 3 h20 healthy adults · 121 g of bread · starch 74% vs 24%amylose · blood sugar over 3 hours
64 mmol/L x 3 h
ORDINARY WHEAT BREAD (24% AMYLOSE STARCH)
39 mmol/L x 3 h
HIGH-AMYLOSE WHEAT BREAD (74% AMYLOSE STARCH)
Source: Belobrajdic et al. · J Nutr, 2019 [5]

The starch in the ordinary wheat bread was 24% amylose and in the high-amylose bread 74%, well past the 50% mark the USDA bread trial found was needed.521

2

Whole, less-processed starches

Moderate evidenceHuman studyReview of 25 randomized trials · international glycemic index tables

How much a starch is cooked and milled matters too. In the same 2021 review, less-cooked starch lowered the blood-sugar response across 6 trials, and intact grains and coarser particles lowered it across 12 trials, compared with more processed versions of the same foods.4 The glycemic index tables show the pattern in an everyday food: porridge made from rolled oats averages 55, and instant oat porridge 79.16 Traditional preparation shows up in the same tables: a sourdough wheat bread tested at 54 and a sprouted-grain bread at 55, each in one test of 10 people, against an average of 75 for white wheat bread.16 Researchers also credit the food's structure: a dense, compact food is digested more slowly than white bread, which falls apart easily during digestion.1

Study takeaway: intact grains and coarser particles lowered the blood-sugar response across 12 trials.

3

Protein and vegetables before the starch

Emerging evidenceHuman studyTwo trials in which each person tried both orders · 11 and 26 adults

In 11 adults with type 2 diabetes on metformin who ate the same meal twice, a week apart, eating the vegetables and protein first and the carbohydrates last kept blood sugar at 60 minutes 36.7% lower, 125.6 against 199.4 mg/dL, with insulin at 63.2 against 125.4 µIU/mL, compared with eating the carbohydrates first.11 In 26 healthy Japanese adults (29 enrolled), eating the side dishes 15 minutes before the rice instead of 15 minutes after it lowered peak blood sugar to 143.3 mg/dL from 169.0; people knew which order they followed.36 The section on how to eat starch shows how to build this into a meal.

Study takeaway: in 11 adults with type 2 diabetes, eating vegetables and protein before the carbohydrates kept blood sugar 36.7% lower an hour after the meal.

4

Cooking, chilling and reheating

Mixed evidenceHuman studyTrials of 15 to 40 adults: healthy, with type 1 diabetes or with high fasting blood sugar

Chilling cooked rice or pasta for 24 hours before reheating lowered the blood-sugar response in three trials, in healthy adults and in adults with type 1 diabetes, while trials of cold rice and chilled potatoes found smaller or no differences on their main measure.6781523 The cooling section below has the numbers.

Study takeaway: chilled and reheated rice lowered the blood-sugar response in a trial of 15 healthy adults.

5

Resistant starch and insulin sensitivity

Mixed evidenceHuman studyThree reviews of 13 to 22 trials · trials of 10 to 68 adults, using supplements

These trials used resistant-starch supplements, mostly high-amylose corn starch, rather than everyday foods. A 2019 review of 13 trials in 428 adults with overweight or obesity found that resistant starch lowered fasting insulin and fasting blood sugar and improved a measure of insulin sensitivity, with LDL cholesterol and HbA1c lower as well.34 A 2021 review of 19 trials found a small drop in fasting blood sugar, 0.09 mmol/L (about 1.6 mg/dL), a larger one at more than 28 grams a day or beyond 8 weeks, and a lower insulin resistance score, while fasting insulin and several other insulin measures didn't change significantly.37 A 2019 review of 22 trials in 670 people found triglycerides 0.10 mmol/L lower in healthy people and body weight 1.29 kilograms lower in type 2 diabetes, both resting on a few trials, and no effect on other markers.38 In single trials, 30 grams a day for 4 weeks raised insulin sensitivity in 10 healthy adults compared with a placebo, by 33% during a test meal,39 in 33 adults with large waists, 15 or 30 grams a day raised it in the 11 men but not in the 22 women, in a trial where neither the people nor the researchers knew who got what, run with the starch's maker,40 and 45 grams a day for 12 weeks didn't change it in the prediabetes trial above.29

Study takeaway: resistant starch lowered fasting insulin in a review of 13 trials in adults with overweight or obesity.

6

Butyrate from gut bacteria

Emerging evidenceHuman studyTwo trials · 50 adults, and 43 adults on potato starch

When resistant starch reaches your colon, bacteria ferment it into short-chain fatty acids, including butyric acid (butyrate). In 50 healthy adults who each ate both diets, one potato side dish a day, compared with refined-grain side dishes, raised a butyrate-making gut bacterium, Roseburia faecis, though stool butyrate itself didn't change.41 A concentrated dose did more: in 43 healthy young adults who took a raw potato starch powder, one of four supplement groups in a 174-person study, about 28 to 34 grams a day of resistant starch raised stool butyrate by 29% on average over 2 weeks, rising in 63% of them, while resistant corn starch and inulin, given to other groups in the same study, didn't raise it significantly.25

Study takeaway: raw potato-starch powder raised stool butyrate by 29% on average in 43 young adults.

Does cooking and cooling starch lower its blood-sugar effect?

Quick answer

Often, yes: in trials in healthy adults and in adults with type 1 diabetes, cooked rice or pasta chilled for 24 hours and then reheated raised blood sugar less than the same food freshly cooked.678 Cooling turns part of the starch into resistant starch, mostly from amylose, which your enzymes can't easily break down and which survives reheating.13

Scientists call this retrogradation. As cooked starch cools, its chains realign into tighter structures. The amylose part forms resistant starch that stays stable up to about 120°C, so it survives reheating, while re-formed amylopectin melts again at 46°C to 65°C and becomes digestible when you reheat it.13

In a trial of 15 healthy adults who each ate both rices without knowing which was which, white rice cooled for 24 hours at 4°C (39°F) and then reheated carried 1.65 grams of resistant starch per 100 grams, against 0.64 grams freshly cooked, and in the 14 people whose blood sugar was analyzed, it lowered the blood-sugar response to 125 from 152 on the trial's measure.6

Chilling cooked rice for 24 hours, then reheating it, lowered the blood-sugar response

Chilling cooked rice for 24 hours, then reheating it, lowered the blood-sugar response15 healthy adults, 14 analyzed · each person ate both · rice cooled 24 hours at 4°C (39°F). Freshly cooked white rice: 152 mmol·min/L; Cooled 24 hours, then reheated: 125 mmol·min/L15 healthy adults, 14 analyzed · each person ate both · ricecooled 24 hours at 4°C (39°F)
152 mmol·min/L
FRESHLY COOKED WHITE RICE
125 mmol·min/L
COOLED 24 HOURS, THEN REHEATED
Source: Sonia, Witjaksono & Ridwan · Asia Pac J Clin Nutr, 2015 [6]Resistant starch rose from 0.64 to 1.65 grams per 100 grams of rice.

A larger rice trial found no gain. In 40 healthy adults who each ate both, rice cooled overnight and eaten cold had a glycemic index of 75, against 70 for hot rice, values the researchers judged equivalent, and the two were digested about equally well.15 The effect was much larger in two trials in adults with type 1 diabetes who use insulin pumps, each with 32 people who ate both versions without knowing which. Long-grain white rice cooled for 24 hours and reheated produced a blood-sugar rise less than half that of fresh rice, 135 against 336 on the trial's measure of the total blood-sugar rise, and cooled and reheated pasta did the same, 211.9 against 524.8.78 The rice trial also saw more low blood-sugar episodes on people's usual insulin doses, which the safety section covers.

Potatoes have their own trial. In 30 women with obesity and elevated fasting blood sugar who each ate both, 250 grams of russet potatoes baked in their skins, chilled for 5 days, then peeled and served cold lowered the insulin response over 2 hours by 17.7% compared with boiled, peeled potatoes served hot, and blood sugar ran lower at 15 and 30 minutes, though total blood sugar over 2 hours, the trial's main measure, didn't differ. A potato-industry group funded it.23

To make cooling work for you, cook rice or potatoes ahead and chill them. Reheat the rice, as the rice trials did, or eat the potatoes cold, as the potato trial did; the next section has the food-safety steps.

How to eat starch so it's easier on your blood sugar

Start with the form of the starch, then the order you eat it in and the portion. As I've said on my show, "Eat your protein and fiber before the carbs, cut the added sugar and the refined flour, and take a 10-minute walk after meals. That will steady your blood sugar."10

  • Choose whole, properly prepared starches. Pick whole starchy vegetables, beans and lentils, and grains that are organic, sprouted or made into sourdough, such as sprouted grain bread, and leave white flour, dried cereal and instant oatmeal behind.9 As I've written, unlike refined starches, whole starchy vegetables such as sweet potatoes, winter squash, pumpkin, carrots and beets release their glucose slowly while delivering antioxidants.42

  • Eat the starch last. Start with vegetables and protein, and leave the rice, potatoes or bread for the end of the meal. My Insulin Resistance & Prediabetes protocol makes this meal order part of its first phase.43

  • Don't eat starch on its own. Pair it with protein and a healthy fat such as olive oil; the same protocol puts carbs eaten on their own on its cut list for the first 30 days.43

  • Keep portions moderate. In my insulin-resistance meal plan, a starch serving is about ½ cup of cooked brown rice or quinoa, ½ cup of cooked beans or lentils, or a sweet potato, eaten with protein and vegetables.43

  • Have your starch earlier in the day. On my show, I've suggested putting carbs at breakfast and lunch, such as a sweet potato with protein and a vegetable at lunch, and keeping dinner very low-carb.10

  • Choose the slower forms. Pick high-amylose rice over sticky or short-grain rice when you can find it, porridge made from rolled or slow-cooked oats over instant, and lentils, chickpeas and sprouted barley often.3517169

  • Cook ahead and chill safely. Refrigerate cooked rice and potatoes within 2 hours, in shallow containers so they cool quickly, eat them within 3 to 4 days, and when you reheat them, bring them to 165°F.44

Questions about starch and blood sugar?

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Who should be careful with these starch changes?

Quick answer

Take extra care if you use insulin or glucose-lowering medication, have celiac disease or a wheat allergy, or have a sensitive gut. Cooled starches and eating carbs last can lower your blood sugar after meals, several grains contain gluten, and raw resistant starch can be hard to digest.7145

In the type 1 diabetes rice trial, 12 of the 32 people (38%) had a low blood-sugar episode after the cooled rice on their usual insulin dose, against 3 (9%) after fresh rice; the pasta trial found no difference in low blood-sugar episodes.78 Wheat, including the ancient wheats einkorn, emmer and spelt, along with rye and barley, contains gluten or related proteins, so these grains stay off the plate in celiac disease whether they're sprouted, fermented or not.1 On my show, I've cautioned that raw potatoes and unripe bananas are very hard to digest, and that you don't want that kind of fiber if you have leaky gut, bloating or gas.45

Check these before you change how you eat starch:
  • Insulin or glucose-lowering medication: Keep taking it as prescribed, check your blood sugar when you change how you cook or order your starches, and let your prescriber adjust the dose as your numbers come down.

  • Celiac disease: Skip wheat, spelt, einkorn, emmer, rye and barley in every form, sprouted and sourdough included, and follow a strict celiac disease diet.

  • Wheat allergy: Skip wheat in every form, including spelt, einkorn and emmer, sprouted and sourdough included, and follow your allergy plan for other grains.

  • Bloating, gas or a sensitive gut: Go easy on raw potato starch and unripe bananas, and add resistant starch a little at a time.

The bottom line

Is amylopectin bad for you?

No. Amylopectin is the main part of the starch in nearly every starchy food, from potatoes and rice to beans and whole grains, and your body turns it into glucose quickly once it's cooked. What it does to your blood sugar depends on the food it comes in: its fiber and structure, its amylose partner, how it's cooked and cooled, and what you eat with it.14

Reach for whole, properly prepared starches, such as sprouted grains, sourdough, beans, lentils and cooked-and-cooled potatoes, eat them after your protein and vegetables, and keep the portion around half a cup. I value the traditional ways of preparing grains, sprouting and fermenting, because they make grains easier to digest.9 If you use insulin or glucose-lowering medication, read the safety section before you change anything.

Prepared the old ways and eaten in the right order, starch can be steady fuel for your day.

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Amylopectin: frequently asked questions

Is amylopectin a starch?

Yes. Amylopectin is the larger of the two molecules that make up starch, about 70% to 75% of most starches, alongside amylose.1

Is amylopectin bad for you?

No. It's the normal, fast-digesting part of nearly every starchy food, and its effect on your blood sugar depends on the food it comes in, how that food is cooked and what you eat with it.14 In a 12-week randomized trial in 68 adults with prediabetes (61 finished), insulin sensitivity didn't differ significantly between amylopectin starch and resistant starch.29

What is the difference between amylose and amylopectin?

Amylopectin is branched and is digested quickly once cooked, while amylose is mostly straight, is digested more slowly and turns into resistant starch when cooked starch cools.113 Most starches are about 20% to 25% amylose and 70% to 75% amylopectin.1

How is amylopectin different from glycogen?

Glycogen is the branched form of glucose your body stores, and it branches more often than amylopectin, at about 9% of its links against about 5%.2 Glycogen's more evenly spread branches keep it water-soluble, while amylopectin's clustered branches are thought to help make starch insoluble.2

Is amylopectin soluble in water?

Not in cold water. Raw starch granules, which are mostly amylopectin, don't dissolve, and the way amylopectin's branches cluster is thought to be one reason.2 Heated in water, the granules swell and lose their crystal structure as the starch gelatinizes.24

Which foods are highest in amylopectin?

The starch in waxy varieties is almost pure amylopectin: glutinous (sticky) rice, waxy corn and waxy barley.216 In other starchy foods, including wheat, rice, corn and potatoes, the starch is about 70% to 75% amylopectin.1

Are potatoes high in amylopectin?

Yes. As in nearly every starchy food, most of the starch in potatoes is amylopectin.1 Cooked and then chilled, they carry more resistant starch: in 30 women with high fasting blood sugar, baked potatoes served chilled lowered the insulin response by 17.7% compared with hot boiled potatoes.23

Is sticky rice bad for blood sugar?

It raises blood sugar quickly: in one test in 12 people, white glutinous rice from Thailand cooked in a rice cooker had a glycemic index of 98, close to pure glucose.16 If you eat it, keep the portion small and eat it after your protein and vegetables, or choose a high-amylose rice when steady blood sugar is your goal.1135

Does reheating cooled rice undo the resistant starch?

No. The resistant starch that forms from amylose as rice cools stays stable up to about 120°C (248°F), so it survives reheating; only the re-formed amylopectin melts again.13 The rice in the trials that lowered blood sugar was cooled for 24 hours and then reheated.67

What is waxy maize starch, and are amylopectin supplements worth it?

Waxy maize starch is corn starch from waxy corn, which makes almost no amylose,2 and the food-first steps on this page are a better place to start than an amylopectin supplement. Taken uncooked, its raw granules digest slowly: in 12 young adults who each tried all three test foods, 50 grams of carbohydrate from uncooked waxy maize starch, stirred into a drinkable gel, raised blood sugar and insulin less over 4 hours than a maltodextrin-and-sugar mix, and insulin less than white bread.46 Once it's cooked, its amylopectin is digested quickly.1

Freshness & method note

October 21, 2026 — Rewrote the page in Dr. Axe's voice, replacing the 2017 version ("Amylopectin: 3 Reasons to Avoid Foods with This Type of Starch"). Replaced the advice to limit amylopectin in all diets with what human feeding trials show about amylopectin, amylose, blood sugar and insulin. Corrected the description of the 1989 USDA trial, whose glucose tolerance test showed no difference between the starches, labeled the rat studies as rat studies, and corrected the statement that each starch molecule is 80% amylopectin (starch is a mixture of two molecules). Replaced the mislabeled list of "low-amylose foods" with glycemic index data and high-amylose varieties, and removed the cholesterol and belly-fat side effects built on studies that didn't test amylopectin, the statement that amylopectin is insoluble, and the unsourced history section. Added how cooking and cooling create resistant starch, where the "amylopectin A" claim about wheat comes from, practical swaps and portions, one safety section, three charts, a diagram and an FAQ, with 46 numbered references.

References

  1. Brouns FJ, van Buul VJ, Shewry PR. Does wheat make us fat and sick? J Cereal Sci. 2013;58(2):209-215. doi:10.1016/j.jcs.2013.06.002
  2. Tetlow IJ, Bertoft E. A Review of Starch Biosynthesis in Relation to the Building Block-Backbone Model. Int J Mol Sci. 2020;21(19):7011. doi:10.3390/ijms21197011. PMID:32977627
  3. Behall KM, Scholfield DJ, Canary J. Effect of starch structure on glucose and insulin responses in adults. Am J Clin Nutr. 1988;47(3):428-32. doi:10.1093/ajcn/47.3.428. PMID:3279746
  4. Cai M, Dou B, Pugh JE, Lett AM, Frost GS. The impact of starchy food structure on postprandial glycemic response and appetite: a systematic review with meta-analysis of randomized crossover trials. Am J Clin Nutr. 2021;114(2):472-487. doi:10.1093/ajcn/nqab098. PMID:34049391
  5. Belobrajdic DP, Regina A, Klingner B, Zajac I, Chapron S, Berbezy P, et al. High-Amylose Wheat Lowers the Postprandial Glycemic Response to Bread in Healthy Adults: A Randomized Controlled Crossover Trial. J Nutr. 2019;149(8):1335-1345. doi:10.1093/jn/nxz067. PMID:31162585
  6. Sonia S, Witjaksono F, Ridwan R. Effect of cooling of cooked white rice on resistant starch content and glycemic response. Asia Pac J Clin Nutr. 2015;24(4):620-5. PMID:26693746
  7. Strozyk S, Rogowicz-Frontczak A, Pilacinski S, LeThanh-Blicharz J, Koperska A, Zozulinska-Ziolkiewicz D. Influence of resistant starch resulting from the cooling of rice on postprandial glycemia in type 1 diabetes. Nutr Diabetes. 2022;12(1):21. doi:10.1038/s41387-022-00196-1. PMID:35429987
  8. Rogowicz-Frontczak A, Strozyk S, Pilacinski S, Koperska A, Le Thanh-Blicharz J, Tanska M, et al. Does Resistant Starch Formed by Cooling Pasta Decrease the Postprandial Glycemic Response in Type 1 Diabetes? A Randomized Single-Blind Crossover Study. Nutrients. 2026;18(7):1152. doi:10.3390/nu18071152. PMID:41978202
  9. Axe J, Rubin J. The Biblio Diet. Hachette Book Group; 2025. ISBN 9781546008439. Food lists, "Grains and starchy carbohydrates" (ebook p. 165); bread chapter ("Why is sourdough bread good for you?"); legumes list.
  10. Axe J. The Real Reason You Wake Up Tired Every Morning. The Dr. Josh Axe Show. 2026 (episode; Dr. Axe at 5:58 and 6:12 of the YouTube upload, https://www.youtube.com/watch?v=UYvHrFB_g50&t=358s).
  11. Shukla AP, Iliescu RG, Thomas CE, Aronne LJ. Food Order Has a Significant Impact on Postprandial Glucose and Insulin Levels. Diabetes Care. 2015;38(7):e98-9. doi:10.2337/dc15-0429. PMID:26106234
  12. Axe J. The Shocking Reason Your Anxiety, Brain Fog & Bloating May Start in Your Gut. The Dr. Josh Axe Show. 2026 (episode; Dr. Axe at 38:48 of the YouTube upload, https://www.youtube.com/watch?v=yumJczZ1_JM&t=2328s).
  13. Boers HM, Seijen Ten Hoorn J, Mela DJ. A systematic review of the influence of rice characteristics and processing methods on postprandial glycaemic and insulinaemic responses. Br J Nutr. 2015;114(7):1035-45. doi:10.1017/S0007114515001841. PMID:26310311
  14. Englyst HN, Kingman SM, Cummings JH. Classification and measurement of nutritionally important starch fractions. Eur J Clin Nutr. 1992;46 Suppl 2:S33-50. PMID:1330528
  15. Wolever TMS, El-Sohemy A, Ezatagha A, Zurbau A, Jenkins AL. Neither low salivary amylase activity, cooling cooked white rice, nor single nucleotide polymorphisms in starch-digesting enzymes reduce glycemic index or starch digestibility: a randomized, crossover trial in healthy adults. Am J Clin Nutr. 2021;114(5):1633-1645. doi:10.1093/ajcn/nqab228. PMID:34293081
  16. Atkinson FS, Foster-Powell K, Brand-Miller JC. International tables of glycemic index and glycemic load values: 2008. Diabetes Care. 2008;31(12):2281-3. doi:10.2337/dc08-1239. PMID:18835944 (Table 1 and online appendix Table A1)
  17. Miller JB, Pang E, Bramall L. Rice: a high or low glycemic index food? Am J Clin Nutr. 1992;56(6):1034-6. doi:10.1093/ajcn/56.6.1034. PMID:1442654
  18. Bohl M, Gregersen S, Li Z, Blennow A, Hebelstrup KH, Hermansen K. High-amylose barley bread improves postprandial glycemia compared to regular barley and wheat bread in subjects with or without type 2 diabetes. Eur J Clin Nutr. 2025;79(10):1000-1006. doi:10.1038/s41430-025-01646-6. PMID:40691269
  19. Behall KM, Howe JC. Effect of long-term consumption of amylose vs amylopectin starch on metabolic variables in human subjects. Am J Clin Nutr. 1995;61(2):334-40. doi:10.1093/ajcn/61.2.334. PMID:7840071
  20. Goddard MS, Young G, Marcus R. The effect of amylose content on insulin and glucose responses to ingested rice. Am J Clin Nutr. 1984;39(3):388-92. doi:10.1093/ajcn/39.3.388. PMID:6364775
  21. Behall KM, Hallfrisch J. Plasma glucose and insulin reduction after consumption of breads varying in amylose content. Eur J Clin Nutr. 2002;56(9):913-20. doi:10.1038/sj.ejcn.1601411. PMID:12209381
  22. Panlasigui LN, Thompson LU, Juliano BO, Perez CM, Yiu SH, Greenberg GR. Rice varieties with similar amylose content differ in starch digestibility and glycemic response in humans. Am J Clin Nutr. 1991;54(5):871-7. doi:10.1093/ajcn/54.5.871. PMID:1951159
  23. Patterson MA, Fong JN, Maiya M, Kung S, Sarkissian A, Nashef N, et al. Chilled Potatoes Decrease Postprandial Glucose, Insulin, and Glucose-dependent Insulinotropic Peptide Compared to Boiled Potatoes in Females with Elevated Fasting Glucose and Insulin. Nutrients. 2019;11(9):2066. doi:10.3390/nu11092066. PMID:31484331
  24. Guo L, Chen H, Zhang Y, Yan S, Chen X, Gao X. Starch granules and their size distribution in wheat: Biosynthesis, physicochemical properties and their effect on flour-based food systems. Comput Struct Biotechnol J. 2023;21:4172-4186. doi:10.1016/j.csbj.2023.08.019. PMID:37675285
  25. Baxter NT, Schmidt AW, Venkataraman A, Kim KS, Waldron C, Schmidt TM. Dynamics of Human Gut Microbiota and Short-Chain Fatty Acids in Response to Dietary Interventions with Three Fermentable Fibers. mBio. 2019;10(1):e02566-18. doi:10.1128/mBio.02566-18. PMID:30696735
  26. Behall KM, Scholfield DJ, Yuhaniak I, Canary J. Diets containing high amylose vs amylopectin starch: effects on metabolic variables in human subjects. Am J Clin Nutr. 1989;49(2):337-44. doi:10.1093/ajcn/49.2.337. PMID:2644803
  27. Byrnes SE, Miller JC, Denyer GS. Amylopectin starch promotes the development of insulin resistance in rats. J Nutr. 1995;125(6):1430-7. doi:10.1093/jn/125.6.1430. PMID:7782895
  28. Wiseman CE, Higgins JA, Denyer GS, Miller JC. Amylopectin starch induces nonreversible insulin resistance in rats. J Nutr. 1996;126(2):410-5. doi:10.1093/jn/126.2.410. PMID:8632213
  29. Peterson CM, Beyl RA, Marlatt KL, Martin CK, Aryana KJ, Marco ML, et al. Effect of 12 wk of resistant starch supplementation on cardiometabolic risk factors in adults with prediabetes: a randomized controlled trial. Am J Clin Nutr. 2018;108(3):492-501. doi:10.1093/ajcn/nqy121. PMID:30010698
  30. Holt SH, Miller JB. Increased insulin responses to ingested foods are associated with lessened satiety. Appetite. 1995;24(1):43-54. doi:10.1016/s0195-6663(95)80005-0. PMID:7741535
  31. Davis W. Wheat Belly: Lose the Wheat, Lose the Weight, and Find Your Path Back to Health. Rodale; 2011. ISBN 9781609611545.
  32. Davis W. Wheat Belly Basics: The Myth of Complex Carbohydrates. Dr. Davis Infinite Health Blog. October 5, 2017.
  33. Axe J. Natural Sunscreens, EMF Exposure, & the Best Dairy Alternatives (Q&A). The Dr. Josh Axe Show. 2024 (episode; Dr. Axe at 8:28 to 9:04).
  34. Wang Y, Chen J, Song YH, Zhao R, Xia L, Chen Y, et al. Effects of the resistant starch on glucose, insulin, insulin resistance, and lipid parameters in overweight or obese adults: a systematic review and meta-analysis. Nutr Diabetes. 2019;9(1):19. doi:10.1038/s41387-019-0086-9. PMID:31168050
  35. Zenel AM, Stewart ML. High Amylose White Rice Reduces Post-Prandial Glycemic Response but Not Appetite in Humans. Nutrients. 2015;7(7):5362-74. doi:10.3390/nu7075225. PMID:26147654
  36. Kurotobi Y, Kuwata H, Matsushiro M, Omori Y, Imura M, Nakatani S, et al. Sequence of Eating at Japanese-Style Set Meals Improves Postprandial Glycemic Elevation in Healthy People. Nutrients. 2025;17(4):658. doi:10.3390/nu17040658. PMID:40004986
  37. Xiong K, Wang J, Kang T, Xu F, Ma A. Effects of resistant starch on glycaemic control: a systematic review and meta-analysis. Br J Nutr. 2021;125(11):1260-1269. doi:10.1017/S0007114520003700. PMID:32959735
  38. Snelson M, Jong J, Manolas D, Kok S, Louise A, Stern R, et al. Metabolic Effects of Resistant Starch Type 2: A Systematic Literature Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2019;11(8):1833. doi:10.3390/nu11081833. PMID:31398841
  39. Robertson MD, Bickerton AS, Dennis AL, Vidal H, Frayn KN. Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism. Am J Clin Nutr. 2005;82(3):559-67. doi:10.1093/ajcn.82.3.559. PMID:16155268
  40. Maki KC, Pelkman CL, Finocchiaro ET, Kelley KM, Lawless AL, Schild AL, et al. Resistant starch from high-amylose maize increases insulin sensitivity in overweight and obese men. J Nutr. 2012;142(4):717-23. doi:10.3945/jn.111.152975. PMID:22357745
  41. DeMartino P, Johnston EA, Petersen KS, Kris-Etherton PM, Cockburn DW. Additional Resistant Starch from One Potato Side Dish per Day Alters the Gut Microbiota but Not Fecal Short-Chain Fatty Acid Concentrations. Nutrients. 2022;14(3):721. doi:10.3390/nu14030721. PMID:35277080
  42. Axe J, Cole W. Heal Your Cells. Avery; 2026. ISBN 9798217181353. "Personalized Nutrition for Cellular Healing" (starchy vegetables, p. 135).
  43. Axe J. Insulin Resistance & Prediabetes: The 90-Day Healing Protocol. DrAxe.com. 2026. Phase 1, "Stabilize" (meal order; "Eating carbs on their own" on its avoid list); "Does meal order really change blood sugar?", p. 12; "Top 10 blood sugar foods", p. 20; "Cut these", p. 22; "The 7-day meal plan", p. 21.
  44. U.S. Department of Agriculture, Food Safety and Inspection Service. Leftovers and Food Safety. Last updated July 31, 2020.
  45. Axe J. Complete Guide to Healing Leaky Gut Naturally. The Dr. Josh Axe Show. 2026 (episode; Dr. Axe at 42:10 to 42:20 of the YouTube upload, https://www.youtube.com/watch?v=5Y4g5CgMDoU&t=2530s).
  46. Sands AL, Leidy HJ, Hamaker BR, Maguire P, Campbell WW. Consumption of the slow-digesting waxy maize starch leads to blunted plasma glucose and insulin response but does not influence energy expenditure or appetite in humans. Nutr Res. 2009;29(6):383-90. doi:10.1016/j.nutres.2009.05.009. PMID:19628104
Dr. Josh Axe

Dr. Josh Axe, DC, DNM, CNS

Doctor of Natural Medicine · Founder, DrAxe.com

Dr. Axe is a certified doctor of natural medicine, clinical nutritionist, and multiple New York Times bestselling author. He has spent 20+ years in clinical practice helping people heal at the root cause and founded one of the most-visited natural-health platforms in the world.

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