When you eat a grapefruit, what do you do with the seeds? I’m guessing you spit them out or remove them from the start. What if I told you that those grapefruit seeds, particularly in grapefruit seed extract (GSE) form, actually might hold a wealth of health benefits.
This makes sense, considering grapefruit benefits include weight loss, cellulite reduction and immune system enhancement. Grapefruit seed extract actually has a different set of benefits almost entirely, but some of them do overlap with the incredible abilities of grapefruit essential oil. Practitioners of alternative medicine say grapefruit seed extract possesses antibacterial, antiviral and antifungal properties and recommended its use for the treatment of candidiasis, earaches, throat infections and diarrhea.
Grapefruit seed extract, especially when used internally, can be somewhat of a controversial supplement due to a lack of human studies as well as evidence of adulteration of grapefruit seed extract. The main controversy stems from study findings that some commercially produced grapefruit seed extracts contain harmful ingredients like benzethonium chloride and triclosan. (1)
Without a doubt, if you’re going to use a grapefruit seed extract product, you should always read ingredients lists carefully and make sure that you buy from a reputable company. While brands might differ when it comes to quality, scientific research shows that pure grapefruit seed extract can kill all kinds of infectious microbes and even helps combat common health issues like candida and athlete’s foot. So are the seeds of a grapefruit actually good for you? Let’s discuss why this citrus fruit’s seedlings might be worthy of attention to your life as an internal, external and household natural remedy.
6 Grapefruit Seed Extract Benefits
1. Fights Candida
Grapefruit seed extract is on my candida diet treatment plan for very good reason. Candidiasis, commonly referred to as “candida,” is a fungal infection that can affect men and women of all ages in various parts of the body. It most commonly occurs in the mouth, ears, nose, toenails, fingernails, gastrointestinal tract and vagina.
A Polish study published in 2001 found that a 33 percent grapefruit extract has a potent antifungal effect against Candida albicans strains taken from patients with candida symptoms. (2) GSE’s antifungal properties help it combat candida infestations by killing the yeast cells that have taken over in the body.
2. Kills Antibiotic-Resistant UTIs
A noteworthy case study published in the Journal of Alternative and Complementary Medicine in 2005 found that grapefruit seeds were highly effective in killing antibiotic-resistant urinary tract infections. The study looked at several patients who were treated with grapefruit seeds (Citrus paradisi) orally for two weeks. The dosage was five to six grapefruit seeds every eight hours.
Within those two weeks, all patients responded satisfactorily to the treatment minus one. However, this patient initially had the bacterial UTI resistant to three different antibiotics, but after taking grapefruit seed there was a reversal of the antibiotic resistance pattern. Although a small human study, the data points toward the antibacterial ability of dried or fresh grapefruit seeds being comparable to proven antibacterial drugs, making it an effective home remedy for UTIs. (3)
3. Remedies Fungal Infections
Histoplasmosis is a fungal infection sometimes mistaken for tuberculosis that’s caused by Histoplasma capsulatum or H. capsulatum, a fungus often found in bird and bat droppings. Histoplasmosis is most commonly transmitted when spores become airborne (often during cleanup or demolition projects) or from dirt contaminated with the droppings. The majority of people who acquire histoplasmosis are symptomless and never even know they’re infected, but some people may develop flu-like symptoms that last around 10 days.
For people with weak immune systems, chronic diseases or for infants, histoplasmosis can be serious. About 500,000 people are exposed to H. capsulatum each year in the U.S.
A recommended alternative treatment for this fungal infection is grapefruit seed extract at a dosage of 100 milligrams (capsule) or five to 10 drops in water three times daily. It’s recommended for its antibacterial, antifungal and antiviral properties. Since GSE likely helps make the immune system stronger, it can help provide symptom release for fungal infections like histoplasmosis.
4. Relieves Athlete’s Foot and Nail Fungus
Athlete’s foot is a skin disease that usually occurs between the toes and is caused by a fungus. As a natural treatment for athlete’s foot, you can try applying full-strength grapefruit seed extract to the problem areas two to three times per day. (4) It shouldn’t take too long to have the itching, burning and general unpleasantness of athlete’s foot under control.
5. Treats Digestive Disturbances Associated with Eczema
Eczema is a common skin disorder that often has links to food choices and digestive issues. One preliminary human trial investigated the effectiveness of grapefruit seed extract on atopic eczema patients who also had intestinal dysbiosis, a microbial imbalance or maladaptation in the digestive tract. All patients showed severe atopic eczema, including bleeding lesions over the face, limbs and trunk, while 14 of 25 also had intermittent diarrhea, constipation, flatulence, intestinal rushes, bloating and abdominal discomfort.
Subjects received either two drops of a 0.5 percent liquid concentrate of grapefruit seed extract twice a day or 150 milligrams of encapsulated grapefruit seed extract (ParaMicrocidin®) three times a day. After a month, all of the subjects taking capsules experienced significant improvements in constipation, flatulence and abdominal discomfort, as well as night rest, while 20 percent of the subjects taking the liquid experienced significant improvements in their negative digestive symptoms. The extract was mostly effective against Candida, Geotrichum sp. and hemolytic E. coli. There were zero side effects during the entire study. (5)
6. Works as a General Antimicrobial
Grapefruit seed extract benefits can be experienced when it’s taken by mouth for bacterial, viral and fungal infections, including yeast infections. (6) But there are also many grapefruit seed uses that don’t involve ingesting the extract. Due to its antimicrobial activities, grapefruit seed extract is commonly included in many throat sprays, nasal sprays, ear drops, mouth washes, toothpastes, shower gels, wound disinfectant sprays and other personal care products. Instead of using unnatural and synthetic preservatives, many natural companies turn to grapefruit seed extract for its ability to preserve a product by killing unwanted bacteria.
Other antimicrobial uses of grapefruit seed extract include:
- In laundry — to kill fungi and bacteria, add 10 to 15 drops to the final rinse
- In carpet cleaners — to kill pathogenic organisms
- Sterilizing and disinfecting operating rooms
- In nebulizers — one drop GSE to one ounce saline water for control of respiratory infections
- In humidifiers — three to four drops per gallon of water to prevent algae growth
- As a better preservative than most chemical preservatives currently on the market
- Disinfecting surfaces — when mixed with water in a spray bottle, it’s great for disinfecting cutting boards and other kitchen as well as bathroom surfaces
- In hot tubs and swimming pools — GSE is added to lessen the need for high levels of chlorine
- Farming — farmers use the extract in animal feed and water to reduce the incidence of infectious diseases
Grapefruit Seed Extract Plant Origin and Nutrition Facts
Grapefruit seed extract, also known as GSE or citrus seed extract, is derived from the seeds, pulp and white membranes of a grapefruit. Grapefruit (Citrus paradisi) seeds comes from a grapefruit, which comes from a grapefruit tree. This is a citrus tree of the Rutaceae family that produces edible fruit.
Grapefruit seed extract is made by mixing grapefruit seeds and pulp into a highly acidic liquid. After some additional processing, the mixture turns into a yellow, thick liquid that has a strong, bitter taste. It’s then typically combined with vegetable glycerin to reduce the bitterness and acidity.
The main biological compounds in a grapefruit seed that are believed to be responsible for its ability to destroy infectious invaders are the polyphenols known as limonoids and naringenin. (7)
You can also get the benefits of GSE by eating the seeds, pulp and white membranes of a grapefruit. The benefits of grapefruit juice are increased when it’s produced fresh including the seeds and membranes.
Related: Berberine: The Plant Alkaloid that Helps Treat Diabetes & Digestive Problems
Grapefruit Seed Extract History and Interesting Facts
- Grapefruit seed extract was discovered by Jacob Harich, an American immunologist, in 1972.
- The grapefruit is a subtropical citrus tree grown for its fruit, which was originally named the “forbidden fruit” of Barbados.
- Grapefruit was first documented in 1750 by Reverend Griffith Hughes describing specimens from Barbados.
- Farmers in Europe use a powdered form of GSE in fish and poultry feed to prevent infections caused by salmonella and E. coli bacteria.
- GSE is used in cosmetic products for its natural antimicrobial abilities.
- Other uses for diluted grapefruit seed extract include as a mouthwash, throat gargle, acne skin cleanser and disinfectant.
- Don’t confuse GSE with the other GSE — grapeseed extract— another supplement entirely. Grapefruit seed extract is from a grapefruit while grapeseed extract, or grapeseed oil, is from a grape.
How to Choose and Use Grapefruit Seed Extract
Grapefruit seed extract is available in supplement form as a liquid concentrate, capsule or tablet. It’s readily available at your local health store or online.
Never purchase a grapefruit seed extract product that contains health-hazardous, synthetic chemicals like methylparaben, benzethonium chloride or triclosan. A typical formula I recommend contains just two ingredients: grapefruit seed extract and vegetable glycerin.
Always speak with your health care provider about proper dosage or follow the instructions provided on the extract. The typical recommended dosage for the liquid extract is 10 to 12 drops in a glass of water (at least five ounces), one to three times daily. For capsules and tablets containing dried grapefruit seed extract, the usual recommendation is 100 to 200 milligrams, one to three times daily. The amount depends on the strength of the GSE and the reason you’re taking it.
Grapefruit seed extract can deplete good bacteria in the gut if it’s taken for long periods of time. If you intend to take it for three or more consecutive days, make sure to also consume a probiotic supplement a few hours before taking your dose of GSE.
Always store your grapefruit seed extract away from heat and direct light.
If you feel unsure about taking supplemental forms of grapefruit seed, you can also eat the seeds (warning: they’re bitter) and white membranes of the grapefruit. You can also include the seeds and membranes when you make fresh grapefruit juice.
Grapefruit Seed Extract Possible Side Effects and Caution
Before using grapefruit seed extract, talk to your doctor if you:
- are currently taking any other medications, especially blood thinners or medicines used after organ transplant
- are allergic to any medicine (prescription or over-the-counter or dietary supplements)
- are pregnant or plan to become pregnant while using this medicine
- are breast-feeding
- have any other health problems, such as high blood pressure or heart/blood vessel disease
Never put the extract into your eyes, and don’t use at full strength in your mouth, ears, nose or sensitive areas. If used in full strength on skin it may cause irritation.
See a doctor right away if you have any signs of a serious allergic reaction after taking GSE. Signs of an allergic reaction include swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, hives or rash.
Grapefruit seed extract is not commonly known to cause any side effects when taken as directed. However, rare side effects of may include nausea, vomiting, swollen or painful tongue, and burns of the mouth, throat or stomach. (8) Discontinue use if you exhibit any negative side effects.
Final Thoughts on Grapefruit Seed Extract
- Grapefruit seed extract, also known as GSE or citrus seed extract, is derived from the seeds, pulp and white membranes of a grapefruit.
- Many professionals, including doctors, veterinarians, farmers and consumers, praise GSE’s multipurpose use and effectiveness.
- Grapefruit seed extract has been shown to posses antibacterial, antiviral, antimicrobial and antifungal properties, and it fights candida, kills antibiotic-resistant UTIs, remedies fungal infections, relieves athletes foot and nail fungus, and treats digestive disturbances associated with eczema.
- If you have candida, it’s best to begin GSE therapy in partnership with a cleansing anti-candida diet. This means avoiding things like sugar, alcohol, dairy and grains.
- NEVER buy a grapefruit seed extract product that contains harmful ingredients like benzethonium chloride, triclosan or methylparaben.