Garcinia Cambogia: Does This Hyped Weight Loss Supplement Really Work?

Garcinia cambogia - Dr. Axe

Garcinia cambogia (GC) is a small pumpkin-shaped fruit that grows in Southeast Asia and India. The key active ingredient found in garcinia cambogia is Hydroxycitric Acid (HCA), which some research suggests can help certain people lose weight. (1)

Currently there are at least 14 separate HCA–containing products sold over-the-counter to consumers labeled as “garcinia cambogia.” Most people are drawn to the idea of using GC because of the potential that it can provide near-effortless, quick weight loss without the need to change someone’s overall diet or lifestyle very much.

GC itself is not a new product; in fact, it’s been consumed in parts of Asia for many years, although not for the purpose of losing weight. Since GC (traditionally also known as the Malabar tamarind) first began to gain popularity in the U.S. several years ago — after appearing frequently in the media and on popular health-related TV shows — sales have gone up dramatically. More and more people are purchasing this so-called “weight loss miracle drug” in hopes of losing stubborn body fat they’ve been struggling with for years.

But just like most other weight-loss supplements, pills and products, studies regarding GC’s effects and safety have been mixed. While there’s some evidence that HCA might be able to aid in weight loss even when someone does not exercise often or change their diet very much, there’s also concerns regarding serious side effects that can occur including liver damage or failure, anxiety, fatigue, dizziness and digestive problems.

Remember that just because GC is derived from a natural fruit doesn’t mean it’s always completely safe. So is garcinia cambogia ultimately worth trying? Let’s take a look at how HCA works, in what situations GC might be helpful, and what adverse reactions are possible when using any type of weight loss drug.

Finally, it’s worth considering the fact that time and time again we see various fad products and diets being publicized to help boost weight loss — but what really works in the end is living a healthy lifestyle long-term.


Does Garcinia Cambogia Work? What The Studies Tell Us

Garcinia cambogia reviews, research results and weight loss testimonials have been mixed to say the least. By far the most well-publicized benefit of using garcinia cambogia is its ability to increase weight loss. Other claims that are commonly made about garcinia cambogia’s effects include:

  • loss of appetite, or less of a desire to eat than usual
  • reduced cravings for unhealthy foods, such as sugar addiction
  • a more positive mood (including feeling happier, more energetic and less tired)
  • increased energy and concentration
  • stabilized blood sugar levels
  • improved bowel movements
  • reduced joint pains
  • improved cholesterol levels
  • stronger desire to be physically active

Most of the claims above have not been backed by scientific studies, however some have. Below are several benefits of garcinia cambogia that actually have some merit:

1. Weight Loss

Some studies have found that garcinia cambogia might, in fact, be able to help with low amounts of fat loss, plus some of the other health concerns mentioned above, although its effects are rarely strong or consistent. For example, research suggests that HCA works by blocking a certain enzyme called adenosine triphosphatase-citrate-lyase, which contributes to the formation of fat cells. But studies comparing GC’s effects to controls have found that it might only increase weight loss by a mere 1–2 pounds on average. These findings are exactly what researchers published in the Journal of Obesity in 2011: When they compared people who took garcinia cambogia extract to those who didn’t, the weight difference was very small (on average just about two pounds). Plus, it wasn’t even possible to conclude that GC was directly responsible for the additional pounds lost. The meta-analysis reviewed results from 12 different trails involving GC and revealed a small, statistically significant difference in weight loss favoring use of garcinia cambogia products containing HCA slightly over use of a placebo. However, the analysis also found that some studies showed digestive side effects (“gastrointestinal adverse events”) were twice as common in  HCA groups compared with placebo! Results from various weight loss studies involving GC have been very mixed. One study in the meta-analysis reported a significant decrease in fat mass in the HCA group compared with placebo, two studies reported a significant decrease in visceral/subcutaneous/total fat areas in the HCA group compared with placebo, but two other studies found no significant difference at all between HCA and placebo. A study that was published in the Journal of the American Medical Association found that GC used for 12 weeks (1500 milligrams dosage) “failed to produce significant weight loss and fat mass loss beyond that observed with placebo.” (2) The conclusion of the meta-analysis regarding garcinia cambogia? Researchers summed up their findings by saying that “the magnitude of the effects are small, and the clinical relevance is uncertain. Future trials should be more rigorous and better reported.” (3) The bottom line is that if you’re struggling to lose weight, GC likely won’t be the answer.

2. Lowering Appetite

Studies have also suggested that it’s possible that HCA found in garcinia cambogia can help lower someone’s appetite by increasing production of the neurotransmitter serotonin, which is associated with calm, happy feelings and. therefore, sometimes appetite suppression, less cravings and reduced desire for comfort foods. Other animal studies show it might also help increase energy expenditure. (4) Keep in mind, however, that this isn’t the case with all people, and that there are other, potentially less-risky ways to better manage your appetite and boost serotonin production (such as beating balanced meals with protein foods and healthy carbs at regular times throughout the day).

What is garcinia cambogia - Dr. Axe

3. Lower Cholesterol

There is some support for garcinia cambogia being able to improve cholesterol levels and lower triglycerides. It might also be able to help raise HDL “good” cholesterol. It’s not safe for anyone already taking medications that affect cholesterol however, and its effects don’t seem to be very reliable or strong. Other studies have found that GC has “no significant effect on anthropometric parameters, REE, triglycerides or glucose levels” but might have a small effect on lowering cholesterol. (5) Keep in mind that there are also plenty of other natural ways to improve cholesterol levels — including exercising and eating more dietary fiber from high-fiber foods like veggies, nuts, seeds and beans.

4. Stabilized Blood Sugar

Finally, what about CG’s effects on blood sugar levels? Some evidence exists showing that garcinia cambogia can help control blood sugar by improving how cells take up glucose (sugar) to be used for energy. One way in which it might improve weight loss is through inhibition of pancreatic alpha amylase enzymes, changes in intestinal alpha glucosidase and alterations in fatty acid synthesis. This might be able to change how carbohydrates are metabolized. (6) This might possibly help your body respond to insulin better, although it can raise the risk for having low blood sugar levels in some people, too. If you have a history of blood sugar swings, you’re pre-diabetic, diabetic or taking medications that alter insulin’s effects, then GC might make your blood sugar drop dangerously low. While this doesn’t appear to happen in everyone who takes GC, it’s something else to consider.


Potential Garcinia Cambogia Side Effects

While some people claim that they don’t experience any side effects at all from using GC, other have had a very different experience. Here’s one disturbing finding regarding the use of garcinia cambogia extract that you might not have heard about: It’s contributed to at least several patients winding up in the hospital with liver failure and needing emergency liver transplants. A 2016 article published by the Transplantation Center at the Mayo Clinic reports that millions of Americans regularly use herbal supplements but aren’t aware of their full effects. Many weight loss drugs pose potential hidden dangers and are “associated with hepatotoxicity and acute liver injury.” (7) In the case of garcinia cambogia, it can easily be overused and is not very well-regulated. Some manufacturers recommend taking high doses multiple times per day, for example 30 to 60 minutes before every meal for 8–12 weeks straight. (8) Aside from liver damage, other garcinia cambogia side effects that can occur include:

  • becoming fuzzy or weak
  • fatigue and brain fog
  • skin rashes
  • an increase in catching colds/lower immune function
  • dry mouth and bad breath
  • headaches
  • digestive issues like nausea, trouble eating or diarrhea

Something else to consider about GC is the long list of its potential medical/drug interactions. Many people should avoid garcinia cambogia due to how it can effect other medications, pregnancy, nutrient levels, blood sugar and more. Garcinia cambogia can potentially interact badly with: (9)

  • pregnancy and breastfeeding
  • existing cases of liver or kidney damage
  • medications that are taken to control asthma and allergies
  • diabetes medications and insulin
  • iron supplements (usually taken by people with anemia)
  • pain medications
  • medications used to control mental disorders like anxiety and depression
  • statin drugs that lower cholesterol
  • blood thinning drugs (like warfarin)

How Much Garcinia Cambogia Should You Take?

If you decide that you still want to try taking GC for weight loss or its other benefits, here’s what you need to know about dosage recommendations for products containing HCA:

  • Studies using GC have used a wide range of doses, anywhere from 1 gram to 2.8 grams daily. Typical doses are uusally between 250–1,000 milligrams per day
  • Study durations have also varied widely, ranging from using GC between 2–12 weeks at a time
  • The optimal dose of HCA is currently still unknown; it’s not clear if a higher HCA dosage even means a higher bioavailability of HCA once consumed
  • There does seem to be a significant correlation between the dosage of HCA and body weight loss, meaning higher doses will have slightly more effects
  • Garcinia cambogia continues to be the most widely used supplement in studies for providing HCA, however aside from GC, HCA can also be found in supplements made from the plant Hibiscus subdariffa
  • Because most studies have investigated the effects of GC taken for about 8 weeks, researchers believe this ultimately “too short a time to assess the effects of HCA on body weight”

To err on the safe side, avoid buying garcinia cambogia “formulas” or “supplement blends,” which might fail to report all of the other ingredients included or accurate levels of HCA. Many proprietary formulas are made by manufacturers that only use a fraction of the active ingredient or standard dose to keep costs down. Always read labels and look for the words “pure garcinia cambogia” and “hydroxycitric acid (or HCA) extract” (this should be around 50-60 percent of the product). If you’re purchasing a blend and see an ingredient listed without an amount, that can be a red flag that you don’t know exactly what you’re getting.

Garcinia cambogia side effects - Dr. Axe

 


11 Weight Loss Methods That Really Do Work!

In just about all studies involving garcinia cambogia, researchers note that it’s hard to tell if any demonstrated benefits (weight loss, reduced cholesterol, etc.) are really due to GC, or are actually influenced by other factors like the subjects eating a lower-calorie diet or exercising. It’s always possible for any supplement to cause a “placebo effect,” where subjects wind up changing their outlook and habits simply because they believe the product is helping them (even if it isn’t actually doing anything). Another interesting fact that the Journal of Obesity meta-analsis reports is that most of the included studies “failed to indicate whether or not outcome assessors were blinded, and seven studies did not even specify who funded the garcinia cambogia studies.”. While it’s possible that garcinia cambogia might help you lose an additional 1–2 pounds if you take it regularly, most experts don’t think it’s worth the money or the risk — especially considering its effects are so small and inconsistent. Ultimately taking weight loss supplements won’t teach you much about eating an overall healthy diet, finding ways to enjoy exercise, or practicing “intuitive eating” and managing cravings. So what can you do to move in the right direction of losing weight safely? Weight loss efforts should always be realistic, safe and sustainable. Remember that the real goal is to reach a healthy weight and stay there for life. That’s why quick-fixes and fad-diets have been shown in studies to fail in the long-run over 95 percent of the time! Here are some of my favorite tips for losing weight using reliable methods that really work:

  1. Get good sleep! A lack of sleep (less than 7–9 hours nightly for most people) can mean a lack of weight loss
  2. Eat more fiber: adults need to aim for at least 25–30 grams daily from things like veggies, fruit, ancient grains, sprouted legumes and seeds
  3. Use healthy fats: coconut oil has natural fat-burning effects just like GC does, plus many more benefits like improving gut health, too. Other healthy fats that can help control your appetite include real olive oil, avocado. fats from grass-fed beef, nuts and seeds
  4. Utilize adaptogen herbs: adaptogen herbs like maca, ginseng and rhodiola can help control health conditions that can make it hard to lose weight (like high amounts of stress, thyroid issues, leaky gut, adrenal fatigue, cellular toxicity and candida)
  5. Don’t skimp on protein: protein foods are satisfying and essential for building muscles; regularly include proteins like cage-free eggs and wild-caught fish in your meals
  6. Consume probiotics: probiotic foods and supplements not only help balance improve digestive health, they also balance hormones, raise immunity, control your appetite and play a part in weight control
  7. Switch up your exercise routine: try burst-training exercises and other forms of high intensity interval training (HIIT) to keep challenging your muscles, work in with a group, add in weight training, and relax with yoga in between workouts
  8. Stand up more during the day: sitting for long periods of time is associated with being overweight and a higher risk for obesity
  9. Sneak more fitness into your day: take the stairs, do body weight exercises at home, or try wearing a fitness tracker for motivation — try some of these exercise hacks
  10. Schedule your workouts ahead of time: this makes it much more likely you’ll follow through
  11. Use essential oils for weight loss: natural oils including grapefruit, cinnamon and ginger oil can help control your appetite, hormones and digestive symptoms

Read Next: Basal Metabolic Rate — What “The Biggest Loser” Can Teach Us


From the sound of it, you might think leaky gut only affects the digestive system, but in reality it can affect more. Because Leaky Gut is so common, and such an enigma, I’m offering a free webinar on all things leaky gut. Click here to learn more about the webinar.


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  1. Daniel says:

    What’s your view on its fluoride detoxification claims? Good for pineal gland they say.

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  1. Daniel says:

    What’s your view on its fluoride detoxification claims? Good for pineal gland they say.

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